SE8901278D0 - PEPTIDE DERIVATIVES - Google Patents

PEPTIDE DERIVATIVES

Info

Publication number
SE8901278D0
SE8901278D0 SE8901278A SE8901278A SE8901278D0 SE 8901278 D0 SE8901278 D0 SE 8901278D0 SE 8901278 A SE8901278 A SE 8901278A SE 8901278 A SE8901278 A SE 8901278A SE 8901278 D0 SE8901278 D0 SE 8901278D0
Authority
SE
Sweden
Prior art keywords
hydrogen
residue
physiologically
formula
peptide
Prior art date
Application number
SE8901278A
Other languages
Swedish (sv)
Other versions
SE8901278L (en
Inventor
R Albert
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB888808442A external-priority patent/GB8808442D0/en
Priority claimed from GB888826452A external-priority patent/GB8826452D0/en
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of SE8901278D0 publication Critical patent/SE8901278D0/en
Publication of SE8901278L publication Critical patent/SE8901278L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/655—Somatostatins
    • C07K14/6555—Somatostatins at least 1 amino acid in D-form
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Hospice & Palliative Care (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Psychiatry (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

Somatostatin peptides containing at least one residue of formula (a), (b) or (c> <IMAGE> wherein one of Y1 and Y2 is hydrogen and the other is hydroxy or both are hydrogen, each of f and g independently is 0 or 1, one of X1 and X2 is hydrogen and the other is hydrogen or an amino protecting group, and X3 is C2-4 alkylene, the free bond in each residue (a), (b) or (c) being located at the N-terminal group of the peptide, and the physiologically-acceptable others and physiologically-hydrolysable and - acceptable esters thereof when the peptide contains at least one residue of formula (a) or (b), in free form, salt form or complex form have pharmacological activity, in particular GH-, gastric and pancreatic secretion inhibiting activity.
SE8901278A 1988-04-11 1989-04-10 PEPTIDE DERIVATIVES SE8901278L (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB888808442A GB8808442D0 (en) 1988-04-11 1988-04-11 Peptide derivatives
GB888826452A GB8826452D0 (en) 1988-11-11 1988-11-11 Peptide derivatives

Publications (2)

Publication Number Publication Date
SE8901278D0 true SE8901278D0 (en) 1989-04-10
SE8901278L SE8901278L (en) 1989-10-12

Family

ID=26293760

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8901278A SE8901278L (en) 1988-04-11 1989-04-10 PEPTIDE DERIVATIVES

Country Status (14)

Country Link
JP (1) JPH01305098A (en)
AU (1) AU3263989A (en)
BE (1) BE1003200A4 (en)
CH (1) CH677795A5 (en)
DE (1) DE3910667A1 (en)
DK (1) DK171489A (en)
ES (1) ES2013431A6 (en)
FR (1) FR2629824B1 (en)
GB (1) GB2224280B (en)
IL (1) IL89897A0 (en)
IT (1) IT1231943B (en)
LU (1) LU87496A1 (en)
NL (1) NL8900882A (en)
SE (1) SE8901278L (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7772188B2 (en) 2003-01-28 2010-08-10 Ironwood Pharmaceuticals, Inc. Methods and compositions for the treatment of gastrointestinal disorders

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4139526A (en) * 1977-12-01 1979-02-13 Merck & Co., Inc. Somatostatin analogs
HUT42101A (en) * 1985-01-07 1987-06-29 Sandoz Ag Process for preparing stomatostatine derivatives and pharmaceutical compositions containing such compounds
JPH085913B2 (en) * 1985-09-12 1996-01-24 ザ・アドミニストレ−タ−ズ・オブ・ザ・ツ−レイン・エデユケイシヨナル・フアンド Therapeutic somatostatin congeners
HU906340D0 (en) * 1986-10-13 1991-04-29 Sandoz Ag Synthesis in solid phase for producing peptonic alcohols

Also Published As

Publication number Publication date
NL8900882A (en) 1989-11-01
JPH01305098A (en) 1989-12-08
DE3910667A1 (en) 1989-10-19
IL89897A0 (en) 1989-12-15
GB8907902D0 (en) 1989-05-24
IT8947833A0 (en) 1989-04-10
IT1231943B (en) 1992-01-16
BE1003200A4 (en) 1992-01-14
FR2629824B1 (en) 1995-03-10
SE8901278L (en) 1989-10-12
AU3263989A (en) 1989-10-12
LU87496A1 (en) 1989-11-14
DK171489D0 (en) 1989-04-10
ES2013431A6 (en) 1990-05-01
GB2224280A (en) 1990-05-02
FR2629824A1 (en) 1989-10-13
GB2224280B (en) 1992-07-08
DK171489A (en) 1989-10-12
CH677795A5 (en) 1991-06-28

Similar Documents

Publication Publication Date Title
FI943233A (en) A variant of a human Kunitz-type protease inhibitor
DK0728148T3 (en) Enhanced immunogenic compositions against human gastrin 17
MX9800418A (en) Analogs of parathyroid hormone.
HK1045161A1 (en) Lhrh antagonist peptides lhrh
NO981395D0 (en) Cyclic peptide analogues of somatostatin
RU94036776A (en) Domain of protease inhibitor, dna, vector, cell, method of protease inhibitor preparing, pharmaceutical composition, the use of protease inhibitor domain
SE9101838D0 (en) NOVEL PEPTIDES AND THEIR USE
TR200101492T2 (en) Antagonistic analogues of GH-RH, which inhibits IGF-I and II
IE852596L (en) Peptides active on the cns
GB1533077A (en) 4-substituted enkephalin derivatives
SE8901278L (en) PEPTIDE DERIVATIVES
ATE42308T1 (en) PHARMACOLOGICALLY ACTIVE PEPTIDES.
DE3467581D1 (en) Gastric secretion inhibiting peptide derivatives, process for their preparation and medicines containing them
ES8801316A1 (en) Novel THF compositions.
CA2076749A1 (en) Vasoactive vasotocin derivatives
ATE45165T1 (en) REDUCED PEPTIDES, GASTRIC RELEASE INHIBITORS, METHOD OF PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM.
NZ511747A (en) Regulatory/unfolding peptides of ezrin
DE3883649T2 (en) Therapeutic analogues of somatostatin.
NO901558L (en) VASOACTIVE PEPTIDES.
ATE162850T1 (en) PHOSPHOLIPASE C INHIBITING PEPTIDE
EP1032585A4 (en) Deoxyhypusine reagent and peptides
ATE87939T1 (en) GLYCOSYLATED AMINO ACIDS AND PEPTIDES.
KR830004213A (en) Method for preparing cactide with biological activity

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 8901278-5

Effective date: 19921101