SE8803567L - RECOMMINARY, RECOMMINATORY, THE SYNTHESIS OF MENO 903 (PPR-IFNBETA-13) - Google Patents

RECOMMINARY, RECOMMINATORY, THE SYNTHESIS OF MENO 903 (PPR-IFNBETA-13)

Info

Publication number
SE8803567L
SE8803567L SE8803567A SE8803567A SE8803567L SE 8803567 L SE8803567 L SE 8803567L SE 8803567 A SE8803567 A SE 8803567A SE 8803567 A SE8803567 A SE 8803567A SE 8803567 L SE8803567 L SE 8803567L
Authority
SE
Sweden
Prior art keywords
ppr
plasmid
beta
construction
size
Prior art date
Application number
SE8803567A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE8803567D0 (en
Inventor
V G Debabov
Original Assignee
Vnii Genetiki Selek
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Vnii Genetiki Selek filed Critical Vnii Genetiki Selek
Publication of SE8803567L publication Critical patent/SE8803567L/en
Publication of SE8803567D0 publication Critical patent/SE8803567D0/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/565—IFN-beta

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)

Abstract

A recombinant plasmid DNA pPR-IFN beta 1-13, coding for synthesis of human beta 1-interferon has a size of 3.9 k.b.p. and consists of the following elements: BamHI-BglII, a fragment of a size of 3.4 k.b.p. of vector plasmid obtained on the basis of pPR40 and pML24, EcoRI-Sau3A, a fragment of plasmid pIN beta -trp 7 of a size of 510 b.p. deposited on 12.01.87 under No. 1825 at the culture collection of the USSR Research Institute for Antibiotics. A method of construction of the above plasmid DNA comprises the preliminary construction of vector plasmid pPR124B, then the construction of intermediary plasmid pPR-IFN beta 1-123 with the subsequent construction of plasmid pPR-IFN beta 1-13. A strain of bacteria Escherichia coli VNIIGENETIKA VL 903 (pPR-IFN beta 1-13) as producer of human beta 1-interferon deposited on 12.01.87 under No. 1825 at the culture collection of the USSR Research Institute for Antibiotics.
SE8803567A 1987-02-09 1988-10-07 REKOMBINANTISK, synthesis of MAENNISKOFIBROBLAST-BETA1 INTERFERON encoding plasmid-DNAPPR-IFN-beta 13, FOERFARANDE bed for constructing NAEMNDA plasmid DNA and MAENNISKO-BETA1 INTERFERON-producing, NAEMNDA plasmid DNA INNEHAALLANDE BACTERIAL strain of the species Escherichia coli VNIIGENETIKA VL 903 (PPR -IFNBETA-13) SE8803567D0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SU874191345A SU1703692A1 (en) 1987-02-09 1987-02-09 Recombination plasmid dna that codes synthesis of fibroblast human interferon and method developing escherichia coli strain, producent of human interferon @@@ 1

Publications (2)

Publication Number Publication Date
SE8803567L true SE8803567L (en) 1988-10-07
SE8803567D0 SE8803567D0 (en) 1988-10-07

Family

ID=21284355

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8803567A SE8803567D0 (en) 1987-02-09 1988-10-07 REKOMBINANTISK, synthesis of MAENNISKOFIBROBLAST-BETA1 INTERFERON encoding plasmid-DNAPPR-IFN-beta 13, FOERFARANDE bed for constructing NAEMNDA plasmid DNA and MAENNISKO-BETA1 INTERFERON-producing, NAEMNDA plasmid DNA INNEHAALLANDE BACTERIAL strain of the species Escherichia coli VNIIGENETIKA VL 903 (PPR -IFNBETA-13)

Country Status (9)

Country Link
JP (1) JPH01502478A (en)
CH (1) CH676996A5 (en)
FI (1) FI884556A (en)
GB (1) GB2208866A (en)
HU (1) HUT50871A (en)
NL (1) NL8820103A (en)
SE (1) SE8803567D0 (en)
SU (1) SU1703692A1 (en)
WO (1) WO1988005819A1 (en)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0593792B2 (en) * 1992-10-14 2004-01-07 Ajinomoto Co., Inc. Novel L-threonine-producing microbacteria and a method for the production of L-threonine
DE602005026854D1 (en) * 2004-12-20 2011-04-21 Cadila Healthcare Ltd PROCESS FOR PRODUCING HIGH LEVELS OF INTERFERON-BETA

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4582800A (en) * 1982-07-12 1986-04-15 Hoffmann-La Roche Inc. Novel vectors and method for controlling interferon expression

Also Published As

Publication number Publication date
JPH01502478A (en) 1989-08-31
SU1703692A1 (en) 1992-01-07
WO1988005819A1 (en) 1988-08-11
GB2208866A (en) 1989-04-19
CH676996A5 (en) 1991-03-28
GB8823728D0 (en) 1988-12-07
HUT50871A (en) 1990-03-28
NL8820103A (en) 1989-01-02
SE8803567D0 (en) 1988-10-07
FI884556A0 (en) 1988-10-04
FI884556A (en) 1988-10-04

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