SE8701457D0 - IMMUNOSTIMULATING TRIPEPTIDES - Google Patents

IMMUNOSTIMULATING TRIPEPTIDES

Info

Publication number
SE8701457D0
SE8701457D0 SE8701457A SE8701457A SE8701457D0 SE 8701457 D0 SE8701457 D0 SE 8701457D0 SE 8701457 A SE8701457 A SE 8701457A SE 8701457 A SE8701457 A SE 8701457A SE 8701457 D0 SE8701457 D0 SE 8701457D0
Authority
SE
Sweden
Prior art keywords
arg
tripeptide
ala
salts
immunostimulating
Prior art date
Application number
SE8701457A
Other languages
Swedish (sv)
Other versions
SE8701457L (en
Inventor
B Brunetti
M Prado
Original Assignee
Ellem Ind Farmaceutica
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ellem Ind Farmaceutica filed Critical Ellem Ind Farmaceutica
Publication of SE8701457D0 publication Critical patent/SE8701457D0/en
Publication of SE8701457L publication Critical patent/SE8701457L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08—Tripeptides
    • C07K5/0815—Tripeptides with the first amino acid being basic
    • C07K5/0817—Tripeptides with the first amino acid being basic the first amino acid being Arg
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)

Abstract

The present invention relates to the use of a tripeptide consisting of L-Ala (alanine) and L-Arg (arginine), or its salts thereof and having the following structure: Arg-Ala-Arg for the preparation of a pharmaceutical composition useful as an immunostimulant. The above tripeptide indeed has a strong immunostimulating activity both on maturation of immature T cells and on T cell function. Compositions comprising this tripeptide or its salts thereof in admixture with a pharmaceutically acceptable carrier are also disclosed.
SE8701457A 1986-04-09 1987-04-07 IMMUNOSTIMULATING TRIPEPTIDES SE8701457L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT20027/86A IT1188646B (en) 1986-04-09 1986-04-09 TRIPEPTIDE WITH IMMUNOSTIMULANT ACTIVITY

Publications (2)

Publication Number Publication Date
SE8701457D0 true SE8701457D0 (en) 1987-04-07
SE8701457L SE8701457L (en) 1987-10-10

Family

ID=11163225

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8701457A SE8701457L (en) 1986-04-09 1987-04-07 IMMUNOSTIMULATING TRIPEPTIDES

Country Status (17)

Country Link
JP (1) JPH0645637B2 (en)
KR (1) KR870010080A (en)
AR (1) AR242799A1 (en)
AT (1) ATA88387A (en)
AU (1) AU597048B2 (en)
BE (1) BE1000263A4 (en)
CA (1) CA1322715C (en)
CH (1) CH676467A5 (en)
DE (1) DE3712050A1 (en)
ES (1) ES2003043A6 (en)
FR (1) FR2597107B1 (en)
GB (1) GB2189491B (en)
GR (1) GR870568B (en)
IE (1) IE59806B1 (en)
IT (1) IT1188646B (en)
NL (1) NL8700827A (en)
SE (1) SE8701457L (en)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
RU2056852C1 (en) * 1994-03-18 1996-03-27 Иван Николаевич Головистиков Agent for treatment of autoimmune diseases with suppressor immunodeficiency and a method of autoimmune diseases treatment
RU2058553C1 (en) * 1994-03-18 1996-04-20 Иван Николаевич Головистиков Method of estimation of human immune status suppressive link
GB0130285D0 (en) * 2001-12-19 2002-02-06 Astrazeneca Ab Chemical process
GB0130286D0 (en) * 2001-12-19 2002-02-06 Astrazeneca Ab Chemical process

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3778426A (en) * 1970-12-16 1973-12-11 Research Corp Therapeutically useful polypeptides
US4215112A (en) * 1979-03-14 1980-07-29 Ortho Pharmaceutical Corporation Tripeptides and methods

Also Published As

Publication number Publication date
JPS62267296A (en) 1987-11-19
DE3712050A1 (en) 1987-10-15
SE8701457L (en) 1987-10-10
CA1322715C (en) 1993-10-05
ES2003043A6 (en) 1988-10-01
IE870881L (en) 1987-10-09
GB2189491B (en) 1990-02-21
GB8708492D0 (en) 1987-05-13
GR870568B (en) 1987-08-12
NL8700827A (en) 1987-11-02
ATA88387A (en) 1996-05-15
JPH0645637B2 (en) 1994-06-15
CH676467A5 (en) 1991-01-31
AR242799A1 (en) 1993-05-31
GB2189491A (en) 1987-10-28
KR870010080A (en) 1987-11-30
IE59806B1 (en) 1994-04-06
IT8620027A0 (en) 1986-04-09
AU597048B2 (en) 1990-05-24
BE1000263A4 (en) 1988-09-27
AU7118287A (en) 1987-10-15
FR2597107A1 (en) 1987-10-16
IT1188646B (en) 1988-01-20
IT8620027A1 (en) 1987-10-09
DE3712050C2 (en) 1992-02-13
FR2597107B1 (en) 1991-02-22

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