SE8504764D0 - MACROPOROSA PARTICLES - Google Patents

MACROPOROSA PARTICLES

Info

Publication number
SE8504764D0
SE8504764D0 SE8504764A SE8504764A SE8504764D0 SE 8504764 D0 SE8504764 D0 SE 8504764D0 SE 8504764 A SE8504764 A SE 8504764A SE 8504764 A SE8504764 A SE 8504764A SE 8504764 D0 SE8504764 D0 SE 8504764D0
Authority
SE
Sweden
Prior art keywords
particles
water
insoluble
generating compound
subsequent
Prior art date
Application number
SE8504764A
Other languages
Swedish (sv)
Other versions
SE8504764L (en
SE464816B (en
Inventor
Kjell Nilsson
Klaus Mosbach
Original Assignee
Kjell Nilsson
Klaus Mosbach
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Kjell Nilsson, Klaus Mosbach filed Critical Kjell Nilsson
Priority to SE8504764A priority Critical patent/SE464816B/en
Publication of SE8504764D0 publication Critical patent/SE8504764D0/en
Priority to DE3689327T priority patent/DE3689327T2/en
Priority to EP86850350A priority patent/EP0222718B1/en
Priority to US06/919,325 priority patent/US4935365A/en
Priority to JP61243321A priority patent/JPH0830124B2/en
Publication of SE8504764L publication Critical patent/SE8504764L/en
Priority to US07/114,421 priority patent/US5015576A/en
Publication of SE464816B publication Critical patent/SE464816B/en

Links

Classifications

    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28002—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their physical properties
    • B01J20/28004—Sorbent size or size distribution, e.g. particle size
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/22—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof comprising organic material
    • B01J20/26—Synthetic macromolecular compounds
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28014—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their form
    • B01J20/28016—Particle form
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28078—Pore diameter
    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J20/00—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof
    • B01J20/28—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties
    • B01J20/28054—Solid sorbent compositions or filter aid compositions; Sorbents for chromatography; Processes for preparing, regenerating or reactivating thereof characterised by their form or physical properties characterised by their surface properties or porosity
    • B01J20/28095—Shape or type of pores, voids, channels, ducts
    • B01J20/28097—Shape or type of pores, voids, channels, ducts being coated, filled or plugged with specific compounds
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J3/00—Processes of treating or compounding macromolecular substances
    • C08J3/12—Powdering or granulating
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J9/00—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof
    • C08J9/28—Working-up of macromolecular substances to porous or cellular articles or materials; After-treatment thereof by elimination of a liquid phase from a macromolecular composition or article, e.g. drying of coagulum
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M25/00—Means for supporting, enclosing or fixing the microorganisms, e.g. immunocoatings
    • C12M25/16—Particles; Beads; Granular material; Encapsulation
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08J—WORKING-UP; GENERAL PROCESSES OF COMPOUNDING; AFTER-TREATMENT NOT COVERED BY SUBCLASSES C08B, C08C, C08F, C08G or C08H
    • C08J2201/00—Foams characterised by the foaming process
    • C08J2201/04—Foams characterised by the foaming process characterised by the elimination of a liquid or solid component, e.g. precipitation, leaching out, evaporation
    • C08J2201/054—Precipitating the polymer by adding a non-solvent or a different solvent
    • C08J2201/0545—Precipitating the polymer by adding a non-solvent or a different solvent from an aqueous solvent-based polymer composition
    • C08J2201/0546—Precipitating the polymer by adding a non-solvent or a different solvent from an aqueous solvent-based polymer composition the non-solvent being organic
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/803—Physical recovery methods, e.g. chromatography, grinding

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Analytical Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Wood Science & Technology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Sustainable Development (AREA)
  • Immunology (AREA)
  • Materials Engineering (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Immobilizing And Processing Of Enzymes And Microorganisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
  • Manufacture Of Porous Articles, And Recovery And Treatment Of Waste Products (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)

Abstract

Particles which enclose cavities can be produced by adding a water-insoluble solid, liquid or gaseous cavity generating compound to an aqueous solution of a matrix material. Subsequent to forming particles by dispersion in a water-insoluble dispersion medium, the matrix is rendered insoluble in water by cooling, by covalent cross-linking or by polymerization. The cavity generating compound is washed out, whereafter the particles can be used as ion exchangers in gel filtration processes, in hydrophobic chromatography or in affinity chromatography, optionally subsequent to derivatizing the particles. The particles can also be used to advantage as microcarriers in the cultivation of anchorage dependent cells.
SE8504764A 1985-10-15 1985-10-15 MACROPOROUS PARTICLES, PROCEDURES FOR ITS PREPARATION AND ITS APPLICATION SE464816B (en)

Priority Applications (6)

Application Number Priority Date Filing Date Title
SE8504764A SE464816B (en) 1985-10-15 1985-10-15 MACROPOROUS PARTICLES, PROCEDURES FOR ITS PREPARATION AND ITS APPLICATION
DE3689327T DE3689327T2 (en) 1985-10-15 1986-10-14 Macroporous particles.
EP86850350A EP0222718B1 (en) 1985-10-15 1986-10-14 Macroporous particles
US06/919,325 US4935365A (en) 1985-10-15 1986-10-15 Macroporous particles for cell cultivation or chromatography
JP61243321A JPH0830124B2 (en) 1985-10-15 1986-10-15 Method for producing large porous particles
US07/114,421 US5015576A (en) 1985-10-15 1987-10-28 Macroporous particles for cell cultivation or chromatography

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE8504764A SE464816B (en) 1985-10-15 1985-10-15 MACROPOROUS PARTICLES, PROCEDURES FOR ITS PREPARATION AND ITS APPLICATION

Publications (3)

Publication Number Publication Date
SE8504764D0 true SE8504764D0 (en) 1985-10-15
SE8504764L SE8504764L (en) 1987-04-16
SE464816B SE464816B (en) 1991-06-17

Family

ID=20361735

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8504764A SE464816B (en) 1985-10-15 1985-10-15 MACROPOROUS PARTICLES, PROCEDURES FOR ITS PREPARATION AND ITS APPLICATION

Country Status (5)

Country Link
US (2) US4935365A (en)
EP (1) EP0222718B1 (en)
JP (1) JPH0830124B2 (en)
DE (1) DE3689327T2 (en)
SE (1) SE464816B (en)

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SE464816B (en) * 1985-10-15 1991-06-17 Nilsson Kjell MACROPOROUS PARTICLES, PROCEDURES FOR ITS PREPARATION AND ITS APPLICATION
JPH0740025B2 (en) * 1988-04-27 1995-05-01 鐘淵化学工業株式会社 Polymer particles for affinity chromatography
EP0370260B1 (en) * 1988-11-23 1994-12-21 Cytec Technology Corp. Porous polymer beads and process
US5073491A (en) * 1988-12-23 1991-12-17 Hoffman-La Roche Inc. Immobilization of cells in alginate beads containing cavities for growth of cells in airlift bioreactors
US5175093A (en) * 1989-11-07 1992-12-29 Lehigh University Bioactive cells immobilized in alginate beads containing voids formed with polyethylene glycol
US5739021A (en) * 1991-07-02 1998-04-14 Pharmacia Biotech Ab Heat-sterilizable porous carrier for biocatalysts
SE9200827D0 (en) * 1992-03-18 1992-03-18 Pharmacia Lkb Biotech SUPET POROUS POLYSACCHARIDE GELS
US5573994A (en) * 1994-05-13 1996-11-12 University Of Cincinnati Superabsorbent foams, and method for producing the same
US5630978A (en) * 1995-06-07 1997-05-20 Yissum Research Development Co. Of The Hebrew University Of Jerusalem Preparation of biologically active molecules by molecular imprinting
US5772874A (en) * 1995-11-02 1998-06-30 Cohesive Technologies, Inc. High performance liquid chromatography method and apparatus
HUP9901311A3 (en) * 1995-12-06 2000-04-28 Dsm Nv Process for the preparation of porous polyolefin particles
EP0840893B1 (en) * 1996-01-19 1999-09-15 Cohesive Technologies Inc. High performance liquid chromatography method and apparatus
NL1007333C1 (en) * 1997-06-05 1999-04-27 Dsm Nv Preparing porous polyolefin particles, used as controlled release carriers
US6110362A (en) * 1997-11-19 2000-08-29 Cohesive Technologies, Inc. Chemical analysis
US6248321B1 (en) * 1999-01-14 2001-06-19 Her Majesty The Queen In Right Of Canada, As Represented By The Minister Of Natural Resources, Canadian Forestry Service Encapsulation of microparticles in teardrop shaped polymer capsules of cellular size
US7115256B1 (en) * 1999-04-09 2006-10-03 Titan Pharmaceuticals, Inc. Methods of treating schizophrenia
CN1091780C (en) * 1999-09-23 2002-10-02 中国科学院化工冶金研究所 Process for preparing macroreticular microcarrier without emulsifier
US6423666B1 (en) * 1999-10-05 2002-07-23 Bio-Rad Laboratories, Inc. Large-pore chromatographic beads prepared by suspension polymerization
US20040185534A1 (en) * 2000-10-02 2004-09-23 Knudsen Ida Molgaard Industrial-scale serum-free production of recombinant proteins in mammalian cells
DE60137950D1 (en) * 2000-10-02 2009-04-23 Novo Nordisk Healthcare Ag METHOD FOR PRODUCING VITAMIN K-DEPENDENT PROTEINS
US20040185535A1 (en) * 2003-03-21 2004-09-23 Giles Wilson Industrial-scale serum-free production of recombinant FVII in mammalian cells
US6916640B2 (en) 2000-10-12 2005-07-12 Agency For Science, Technology And Research Multi-layer cell encapsulation for tissue engineering
SE0004612D0 (en) * 2000-12-14 2000-12-14 Terminus Biotec Ab Biocompatible, porous material, process for its preparation and use thereof
PL368119A1 (en) * 2001-10-02 2005-03-21 Novo Nordisk Health Care Ag Method for production of recombinant proteins in eukaryote cells
BR0312132A (en) 2002-06-11 2005-04-05 Celltrix Ab Porous gelatin material, gelatin structures, methods for preparing them and uses for them
SE0202016D0 (en) * 2002-06-27 2002-06-27 Amersham Biosciences Ab Polymeric Support Having Novel Pore Structures
US20070172821A1 (en) * 2002-08-23 2007-07-26 Li-Qun Wu Assembly of chitosan onto an electrode surface
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WO2004028682A2 (en) * 2002-09-27 2004-04-08 Carlsberg A/S Spatially encoded polymer matrix
US7790010B2 (en) * 2002-12-20 2010-09-07 University Of Maryland, College Park Spatially selective deposition of polysaccharide layer onto patterned template
US7883615B2 (en) * 2003-02-12 2011-02-08 University Of Maryland, College Park Controlled electrochemical deposition of polysaccharide films and hydrogels, and materials formed therefrom
EA012141B1 (en) * 2003-11-21 2009-08-28 Бейкер Хьюз Инкорпорейтед Method and apparatus downhole fluid analysis using molecularly imprinted polymers
US7375404B2 (en) * 2003-12-05 2008-05-20 University Of Maryland Biotechnology Institute Fabrication and integration of polymeric bioMEMS
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US9115238B2 (en) * 2009-05-28 2015-08-25 Corning Incorporated Swellable synthetic microcarriers for culturing cells
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Also Published As

Publication number Publication date
SE8504764L (en) 1987-04-16
JPS62169837A (en) 1987-07-27
EP0222718B1 (en) 1993-11-24
SE464816B (en) 1991-06-17
JPH0830124B2 (en) 1996-03-27
DE3689327D1 (en) 1994-01-05
US4935365A (en) 1990-06-19
EP0222718A2 (en) 1987-05-20
US5015576A (en) 1991-05-14
EP0222718A3 (en) 1988-12-14
DE3689327T2 (en) 1994-06-16

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