SE8306808L - PROCEDURE AND COMPOSITION FOR EVALUATION OF PHAGOCYTIC RESPONSE - Google Patents

PROCEDURE AND COMPOSITION FOR EVALUATION OF PHAGOCYTIC RESPONSE

Info

Publication number
SE8306808L
SE8306808L SE8306808A SE8306808A SE8306808L SE 8306808 L SE8306808 L SE 8306808L SE 8306808 A SE8306808 A SE 8306808A SE 8306808 A SE8306808 A SE 8306808A SE 8306808 L SE8306808 L SE 8306808L
Authority
SE
Sweden
Prior art keywords
cells
light
composition
phagocytic
organism
Prior art date
Application number
SE8306808A
Other languages
Unknown language ( )
Swedish (sv)
Other versions
SE8306808D0 (en
Inventor
J J Capone
Original Assignee
Packard Instrument Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Packard Instrument Co Inc filed Critical Packard Instrument Co Inc
Publication of SE8306808D0 publication Critical patent/SE8306808D0/en
Publication of SE8306808L publication Critical patent/SE8306808L/en

Links

Classifications

    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/5005—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells
    • G01N33/5091—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving human or animal cells for testing the pathological state of an organism

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biomedical Technology (AREA)
  • Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Physiology (AREA)
  • Biotechnology (AREA)
  • Food Science & Technology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Investigating Or Analysing Materials By The Use Of Chemical Reactions (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)

Abstract

A method and composition for measuring the ability of an organism to resist infection are described. A sample of blood cells is taken from an organism. The phagocytic activity of the phagocytes in the blood is estimated by mixing the cells with zymosan particles or polymeric beads coated with protein and a luminescent chemical. When the phagocytic cells are mixed with either of these compositions, the cells engulf the particles thus causing the activation of the cells' biochemical mechanisms. Oxygen intermediates result from this mechanism causing a reaction with the luminescent chemical resulting in the production of light. This light is measured on a luminometer and based on the rate of light production and the maximum produced, the phagocytic activity of said cells is measured.
SE8306808A 1982-12-14 1983-12-09 PROCEDURE AND COMPOSITION FOR EVALUATION OF PHAGOCYTIC RESPONSE SE8306808L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44970982A 1982-12-14 1982-12-14

Publications (2)

Publication Number Publication Date
SE8306808D0 SE8306808D0 (en) 1983-12-09
SE8306808L true SE8306808L (en) 1984-06-15

Family

ID=23785187

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8306808A SE8306808L (en) 1982-12-14 1983-12-09 PROCEDURE AND COMPOSITION FOR EVALUATION OF PHAGOCYTIC RESPONSE

Country Status (9)

Country Link
JP (1) JPS59132361A (en)
AU (1) AU2217783A (en)
CA (1) CA1210328A (en)
DE (1) DE3344607A1 (en)
FI (1) FI834603A (en)
FR (1) FR2537723A1 (en)
GB (1) GB2131948B (en)
IT (1) IT1169988B (en)
SE (1) SE8306808L (en)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6036962A (en) * 1983-08-09 1985-02-26 Toray Ind Inc Fine particle for biological inspection
FI853606A0 (en) * 1984-09-21 1985-09-16 Johnathan L Kiel MICROLUMINISCENT ANALYSSYSTEM
CA2097952C (en) * 1993-06-08 2006-03-14 Alex D. Romaschin Early diagnosis of sepsis utilizing antigen-antibody interactions amplified by whole blood chemiluminescence
US5804370A (en) * 1994-06-08 1998-09-08 Critichem Medical Products Limited Early diagnosis of sepsis utilizing antigen-antibody interactions amplified by whole blood chemiluminescence
US6203997B1 (en) 1994-06-08 2001-03-20 Sepsis, Inc. Quantitation of analytes in whole blood
US6159683A (en) * 1997-12-16 2000-12-12 Spectral Diagnostics, Inc. Method of determining stage of sepsis
GB9910975D0 (en) 1999-05-13 1999-07-14 Univ Strathclyde Rapid dehydration of proteins

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3327119A (en) * 1964-03-26 1967-06-20 Ibm Method and apparatus for detecting cancer cells
US4146604A (en) * 1973-05-31 1979-03-27 Block Engineering, Inc. Differential counting of leukocytes and other cells
DE2732272C2 (en) * 1977-07-16 1979-07-05 Deutsches Krebsforschungszentrum Stiftung Des Oeffentlichen Rechts, 6900 Heidelberg Method and device for fluorescence analysis of colored particles, in particular biological cells
US4336029A (en) * 1980-08-15 1982-06-22 Ortho Diagnostic Systems Inc. Method and reagents for quantitative determination of reticulocytes and platelets in whole blood

Also Published As

Publication number Publication date
SE8306808D0 (en) 1983-12-09
GB2131948A (en) 1984-06-27
IT1169988B (en) 1987-06-03
IT8324159A0 (en) 1983-12-14
GB8332404D0 (en) 1984-01-11
JPS59132361A (en) 1984-07-30
GB2131948B (en) 1986-06-04
DE3344607A1 (en) 1984-06-14
FI834603A (en) 1984-06-15
CA1210328A (en) 1986-08-26
AU2217783A (en) 1984-06-21
FI834603A0 (en) 1983-12-14
FR2537723A1 (en) 1984-06-15
IT8324159A1 (en) 1985-06-14

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