SE8006413L - NEW CEPHALOSPORINES - Google Patents
NEW CEPHALOSPORINESInfo
- Publication number
- SE8006413L SE8006413L SE8006413A SE8006413A SE8006413L SE 8006413 L SE8006413 L SE 8006413L SE 8006413 A SE8006413 A SE 8006413A SE 8006413 A SE8006413 A SE 8006413A SE 8006413 L SE8006413 L SE 8006413L
- Authority
- SE
- Sweden
- Prior art keywords
- formula
- cephalosporines
- new
- new cephalosporines
- mercaptotetrazole
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D257/00—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
- C07D257/02—Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
- C07D257/04—Five-membered rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/54—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
- A61K31/542—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
- A61K31/545—Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
- C07D501/14—Compounds having a nitrogen atom directly attached in position 7
- C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
- C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
- C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
- C07D501/36—Methylene radicals, substituted by sulfur atoms
Abstract
The cephalosporin derivatives of the formula I in which the symbols have the meanings stated in Claim 1 are antibiotics. They are prepared from the 7-acylaminocephalosporanic acid of the formula II by replacement of the acetoxy group by the appropriately substituted 5-mercaptotetrazole.
Claims (1)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US62716475A | 1975-10-30 | 1975-10-30 | |
US66583776A | 1976-03-11 | 1976-03-11 | |
US05/704,142 US4118491A (en) | 1976-03-11 | 1976-07-12 | 7-Acyl-3-(sulfaminoalkyl substituted tetrazolylthiomethyl)cephalosporins, antibacterial compositions containing them and methods of treating bacterial infections with them |
Publications (2)
Publication Number | Publication Date |
---|---|
SE8006413L true SE8006413L (en) | 1980-09-12 |
SE452621B SE452621B (en) | 1987-12-07 |
Family
ID=27417417
Family Applications (3)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE8006413A SE452621B (en) | 1975-10-30 | 1976-09-28 | 7-AMINO CEPHALOSPORINE DERIVATIVES FOR USE AS INTERMEDIATE PRODUCTS FOR THE PREPARATION OF SIMILAR 7-SUBSTITUTED CEPHALOSPORINE DERIVATIVES |
SE7610722A SE435291B (en) | 1975-10-30 | 1976-09-28 | PROCEDURE FOR PREPARING 7-ACYLAMINO-3 (1- (2-SULFAMINOETHYL) -TETRAZOL-5-YLTIOMETHYL) -3-CEFEM-4-CARBONIC ACID |
SE8006414A SE437025B (en) | 1975-10-30 | 1980-09-12 | 1- (2-SULFAMINOETHYL) -TETRAZOL-5-THIOL USED FOR THE PREPARATION OF CEPHALOSPORINE COMPOUNDS WITH ANTIBACTERIAL ACTIVITY |
Family Applications After (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE7610722A SE435291B (en) | 1975-10-30 | 1976-09-28 | PROCEDURE FOR PREPARING 7-ACYLAMINO-3 (1- (2-SULFAMINOETHYL) -TETRAZOL-5-YLTIOMETHYL) -3-CEFEM-4-CARBONIC ACID |
SE8006414A SE437025B (en) | 1975-10-30 | 1980-09-12 | 1- (2-SULFAMINOETHYL) -TETRAZOL-5-THIOL USED FOR THE PREPARATION OF CEPHALOSPORINE COMPOUNDS WITH ANTIBACTERIAL ACTIVITY |
Country Status (17)
Country | Link |
---|---|
JP (1) | JPS6053026B2 (en) |
AT (1) | AT353957B (en) |
AU (1) | AU505141B2 (en) |
CA (1) | CA1071188A (en) |
CH (1) | CH627757A5 (en) |
DE (1) | DE2649545A1 (en) |
DK (1) | DK463176A (en) |
ES (1) | ES452769A1 (en) |
FI (1) | FI60868C (en) |
FR (3) | FR2361896A1 (en) |
GB (3) | GB1570095A (en) |
GR (1) | GR61667B (en) |
IE (1) | IE44393B1 (en) |
IL (3) | IL50546A (en) |
LU (1) | LU76092A1 (en) |
NL (1) | NL7612010A (en) |
SE (3) | SE452621B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4117123A (en) * | 1977-06-09 | 1978-09-26 | Smithkline Corporation | 7-Acylamino-3-[1-(2-sulfamidoethyl)tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acids |
AT383811B (en) * | 1983-09-22 | 1987-08-25 | Biochemie Gmbh | Process for the preparation of monoalkali metal salts of 7-amino-3-cephem-4-carboxylic acid derivatives |
US4717531A (en) * | 1983-09-23 | 1988-01-05 | Westinghouse Electric Corp. | Fuel transfer system upender using translation drive |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AR207752A1 (en) * | 1973-03-30 | 1976-10-29 | Fujisawa Pharmaceutical Co | PROCEDURE FOR OBTAINING 7-AMINO-SUBSTITUTED-3-THIOMETHYL SUBSTITUTED-3-CEFEM-4-CARBOXYL ACIDS |
NL7414119A (en) * | 1973-10-31 | 1975-05-02 | Fujisawa Pharmaceutical Co | PROCESS FOR PREPARING 1H-TETRAZOL-5-THIOL DERIVATIVES AND 1-SUBSTITUATED 1H-TETRAZOL-5-THIOLS. |
GB1449420A (en) * | 1973-11-26 | 1976-09-15 | Sankyo Co | 7alpha-methoxycephalosporing derivatives |
NZ176206A (en) * | 1973-12-25 | 1978-03-06 | Takeda Chemical Industries Ltd | Cephalosporins |
US4066762A (en) * | 1976-07-12 | 1978-01-03 | Smithkline Corporation | Derivatives of 7-(2-substituted-2-hydroxyiminoacetamido)-3-(1-substituted tetrazol-5-ylthiomethyl-3-cephem-4-carboxylic acid |
-
1976
- 1976-09-23 IL IL50546A patent/IL50546A/en unknown
- 1976-09-28 SE SE8006413A patent/SE452621B/en not_active IP Right Cessation
- 1976-09-28 SE SE7610722A patent/SE435291B/en not_active IP Right Cessation
- 1976-09-30 CA CA262,347A patent/CA1071188A/en not_active Expired
- 1976-10-14 DK DK463176A patent/DK463176A/en not_active Application Discontinuation
- 1976-10-14 AU AU18702/76A patent/AU505141B2/en not_active Ceased
- 1976-10-21 FR FR7631723A patent/FR2361896A1/en active Granted
- 1976-10-26 GB GB19863/79A patent/GB1570095A/en not_active Expired
- 1976-10-26 FI FI763044A patent/FI60868C/en not_active IP Right Cessation
- 1976-10-26 GB GB44441/76A patent/GB1570093A/en not_active Expired
- 1976-10-26 GB GB19786/79A patent/GB1570094A/en not_active Expired
- 1976-10-27 IE IE2377/76A patent/IE44393B1/en unknown
- 1976-10-27 ES ES452769A patent/ES452769A1/en not_active Expired
- 1976-10-28 LU LU76092A patent/LU76092A1/xx unknown
- 1976-10-29 JP JP51131157A patent/JPS6053026B2/en not_active Expired
- 1976-10-29 CH CH1369576A patent/CH627757A5/en not_active IP Right Cessation
- 1976-10-29 DE DE19762649545 patent/DE2649545A1/en not_active Ceased
- 1976-10-29 GR GR52030A patent/GR61667B/en unknown
- 1976-10-29 AT AT807276A patent/AT353957B/en not_active IP Right Cessation
- 1976-10-29 NL NL7612010A patent/NL7612010A/en not_active Application Discontinuation
-
1977
- 1977-03-22 FR FR7708505A patent/FR2337720A1/en active Granted
- 1977-03-22 FR FR7708504A patent/FR2351982A1/en active Granted
-
1979
- 1979-02-28 IL IL56757A patent/IL56757A0/en unknown
- 1979-02-28 IL IL56758A patent/IL56758A0/en unknown
-
1980
- 1980-09-12 SE SE8006414A patent/SE437025B/en not_active IP Right Cessation
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
NUG | Patent has lapsed |
Ref document number: 8006413-2 Effective date: 19890426 Format of ref document f/p: F |