SE7906721L - NEW D-HOMOSTEROIDS - Google Patents

NEW D-HOMOSTEROIDS

Info

Publication number
SE7906721L
SE7906721L SE7906721A SE7906721A SE7906721L SE 7906721 L SE7906721 L SE 7906721L SE 7906721 A SE7906721 A SE 7906721A SE 7906721 A SE7906721 A SE 7906721A SE 7906721 L SE7906721 L SE 7906721L
Authority
SE
Sweden
Prior art keywords
homosteroids
ring
beta
acyl
formula
Prior art date
Application number
SE7906721A
Other languages
Swedish (sv)
Inventor
A Furst
M Muller
U Kerb
R Wiechert
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE7906721L publication Critical patent/SE7906721L/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C07J21/005—Ketals
    • C07J21/006—Ketals at position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
    • C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
    • C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Steroid Compounds (AREA)

Abstract

D-Homosteroids with hormonal activity and the formula in which the dotted lines in the A ring are optional C-C bonds; R<3> is oxo if ring A is saturated or is oxo, ( alpha -H, beta -OH) or ( alpha -H, beta -O-acyl) if ring A is unsaturated; R<17a beta > is hydrogen, C1-10-alkyl, benzyl, cyclohexylmethyl, acyl, tetrahydropyranyl or cycloalkenyl are prepared in a manner known per se starting from corresponding 17a-keto- or 3,17a-diketo-D-homosteroids.

Claims (1)

PATENTRRAV.PATENTRRAV. 1. forfarande for framstdllning av D-homosteroider med formeln van i den streckade linjen i A-ringen betecknar en fakultativ C-C-bindning, R1 betecknar vdte eller metyl, R17M beteeknar vAte, acyl, tetrahydropyranyl eller cykloalkenyl och R17" betecknar *irate, lAgre alkyl, etynyl, vinyl eller propadieny1, kdnnetecknat ddrav, att man consdtter en D,homosteroid med formelnA process for the preparation of D-homosteroids of the formula van in the dashed line of the A-ring denotes an optional CC bond, R1 denotes hydrogen or methyl, R17M denotes hydrogen, acyl, tetrahydropyranyl or cycloalkenyl and R17 "denotes * irate, lAgre alkyl, ethynyl, vinyl or propadienyl, characterized in that a D, homosteroid of the formula
SE7906721A 1975-11-11 1979-08-10 NEW D-HOMOSTEROIDS SE7906721L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1456475A CH616436A5 (en) 1975-11-11 1975-11-11 Process for the preparation of D-homosteroids.

Publications (1)

Publication Number Publication Date
SE7906721L true SE7906721L (en) 1979-08-10

Family

ID=4401882

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7604501A SE7604501L (en) 1975-11-11 1976-04-15 NEW D-HOMOSTEROIDS
SE7612263A SE7612263L (en) 1975-11-11 1976-11-03 NEW D-HOMOSTEROIDS
SE7906721A SE7906721L (en) 1975-11-11 1979-08-10 NEW D-HOMOSTEROIDS

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SE7604501A SE7604501L (en) 1975-11-11 1976-04-15 NEW D-HOMOSTEROIDS
SE7612263A SE7612263L (en) 1975-11-11 1976-11-03 NEW D-HOMOSTEROIDS

Country Status (8)

Country Link
BE (1) BE848178A (en)
CH (3) CH616436A5 (en)
DK (2) DK156676A (en)
ES (1) ES461324A1 (en)
FI (1) FI56019C (en)
NO (2) NO761308L (en)
SE (3) SE7604501L (en)
ZA (1) ZA766619B (en)

Also Published As

Publication number Publication date
NO761308L (en) 1977-05-12
CH624128A5 (en) 1981-07-15
DK156676A (en) 1977-05-12
CH616436A5 (en) 1980-03-31
CH626098A5 (en) 1981-10-30
ZA766619B (en) 1977-10-26
ES461324A1 (en) 1978-04-16
NO763545L (en) 1977-05-12
SE7604501L (en) 1977-05-12
FI56019C (en) 1979-11-12
FI56019B (en) 1979-07-31
DK506176A (en) 1977-05-12
BE848178A (en) 1977-05-10
FI761038A (en) 1977-05-12
SE7612263L (en) 1977-05-12

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