SE7805011L - 4-aminometyl-1-(3,3,3-triarylpropyl)-4-arylpiperidin och derivat derav - Google Patents

4-aminometyl-1-(3,3,3-triarylpropyl)-4-arylpiperidin och derivat derav

Info

Publication number
SE7805011L
SE7805011L SE7805011A SE7805011A SE7805011L SE 7805011 L SE7805011 L SE 7805011L SE 7805011 A SE7805011 A SE 7805011A SE 7805011 A SE7805011 A SE 7805011A SE 7805011 L SE7805011 L SE 7805011L
Authority
SE
Sweden
Prior art keywords
triarylpropyl
arylpiperidine
aminomethyl
derivatives
Prior art date
Application number
SE7805011A
Other languages
English (en)
Swedish (sv)
Inventor
G W Adelstein
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of SE7805011L publication Critical patent/SE7805011L/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/08Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
    • C07D211/18Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D211/26Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D211/00Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/06Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
    • C07D211/36Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D211/60Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D211/62Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
    • C07D211/64Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Hydrogenated Pyridines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7805011A 1977-05-02 1978-05-02 4-aminometyl-1-(3,3,3-triarylpropyl)-4-arylpiperidin och derivat derav SE7805011L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/792,616 US4069223A (en) 1977-05-02 1977-05-02 4-Aminomethyl-1-(3,3,3-triarylpropyl)-4-arylpiperidine and derivatives thereof

Publications (1)

Publication Number Publication Date
SE7805011L true SE7805011L (sv) 1978-11-03

Family

ID=25157505

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7805011A SE7805011L (sv) 1977-05-02 1978-05-02 4-aminometyl-1-(3,3,3-triarylpropyl)-4-arylpiperidin och derivat derav

Country Status (10)

Country Link
US (1) US4069223A (cs)
JP (1) JPS549281A (cs)
AU (1) AU520250B2 (cs)
CA (1) CA1105465A (cs)
DE (1) DE2819210A1 (cs)
FR (1) FR2389605B1 (cs)
GB (1) GB1581923A (cs)
NL (1) NL7804725A (cs)
SE (1) SE7805011L (cs)
ZA (1) ZA782514B (cs)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS53125944U (cs) * 1977-12-22 1978-10-06
US4173641A (en) * 1978-05-15 1979-11-06 Pfizer Inc. Di-O-n-alkyl glycerol derivatives as immune stimulants
US5962477A (en) * 1994-04-12 1999-10-05 Adolor Corporation Screening methods for cytokine inhibitors
US6190691B1 (en) 1994-04-12 2001-02-20 Adolor Corporation Methods for treating inflammatory conditions
US6573282B1 (en) 1995-09-12 2003-06-03 Adolor Corporation Peripherally active anti-hyperalgesic opiates
US5849761A (en) * 1995-09-12 1998-12-15 Regents Of The University Of California Peripherally active anti-hyperalgesic opiates
US6353004B1 (en) 1997-07-14 2002-03-05 Adolor Coporation Peripherally acting anti-pruritic opiates
US5849762A (en) * 1997-07-14 1998-12-15 Adolor Corporation Peripherally acting anti-pruritic opiates
US20030158220A1 (en) * 1997-11-03 2003-08-21 Foss Joseph F. Use of methylnaltrexone and related compounds to treat chronic opioid use side effects
EP1377293B1 (en) * 2001-04-12 2010-03-10 Pharmacopeia, LLC Aryl and biaryl piperidines used as mch antagonists
ES2528669T3 (es) * 2003-04-08 2015-02-11 Progenics Pharmaceuticals, Inc. Formulaciones farmacéuticas que contienen metilnaltrexona
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
AR057035A1 (es) * 2005-05-25 2007-11-14 Progenics Pharm Inc SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS
EP1749528A1 (en) 2005-08-05 2007-02-07 Pharma C S.A. Pharmaceutical combinations containing a mu opioid agonist and an inhibitor of NO production
TWI489984B (zh) 2006-08-04 2015-07-01 Wyeth Corp 用於非經腸道傳輸化合物之配方及其用途
TW200817048A (en) * 2006-09-08 2008-04-16 Wyeth Corp Dry powder compound formulations and uses thereof
HUE025662T2 (en) 2007-03-29 2016-04-28 Wyeth Llc Peripheral opioid receptor and antagonists and their uses
CA2682129A1 (en) * 2007-03-29 2008-10-09 Progenics Pharmaceuticals, Inc. Crystal forms and uses thereof
WO2008121348A2 (en) 2007-03-29 2008-10-09 Progenics Pharmaceuticals, Inc. Peripheral opioid receptor antagonists and uses thereof
KR101581480B1 (ko) * 2008-02-06 2015-12-30 프로제닉스 파머슈티컬스, 인코포레이티드 (r),(r)-2,2'-비스-메틸날트렉손의 제조법 및 용도
CA2676881C (en) 2008-09-30 2017-04-25 Wyeth Peripheral opioid receptor antagonists and uses thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1125112A (en) 1966-01-07 1968-08-28 Science Union & Cie New derivatives of diazabicyclo-decane and process for preparing them
US3998832A (en) * 1975-04-16 1976-12-21 G. D. Searle & Co. Anti-diarrheal compounds

Also Published As

Publication number Publication date
GB1581923A (en) 1980-12-31
US4069223A (en) 1978-01-17
FR2389605A1 (cs) 1978-12-01
DE2819210A1 (de) 1979-02-08
NL7804725A (nl) 1978-11-06
ZA782514B (en) 1979-06-27
AU3562278A (en) 1979-11-08
CA1105465A (en) 1981-07-21
AU520250B2 (en) 1982-01-21
FR2389605B1 (cs) 1981-07-17
JPS549281A (en) 1979-01-24

Similar Documents

Publication Publication Date Title
FI782880A7 (fi) Selektiva hydreringsprodukter av c-076-foereningar och av deras derivat
SE7805879L (sv) Mevalonolaktonderivat
DK370778A (da) Triphenylakenderivater
SE7805011L (sv) 4-aminometyl-1-(3,3,3-triarylpropyl)-4-arylpiperidin och derivat derav
FI783931A7 (fi) Aromatiska derivat farmaceutiska blandningar och foerfaranden foer att motverka virusinfektioner
FI782403A7 (fi) Alfa-azolylsulfider och deras derivat
FI782081A7 (fi) N-substituerade estrar av 9,10-dihydrolyserinsyror och foerfarande foer deras framstaellning
SE7803057L (sv) Bensimidazolderivat
DK543178A (da) Thiodydantoinderivater
SE7804446L (sv) Tienamycinderivat
FI780437A7 (fi) Foerfarande foer framstaellning av heteromonocykliska och heterobicykliska derivat av omaettad 7-acylamido-3-kefem-karboxyl-syra
FI783033A7 (fi) Foerfarande foer framstaellning av 4,5-dihydro-2-alkoxi-karbonylamino-5-karbocyklisk-aryl-imidatsoler och deras derivat
SE7805260L (sv) Alkylendiaminderivat
SE7801997L (sv) Dipeptidderivat
SE7810312L (sv) Fenylisotiocyanatderivat och framstellning derav
SE7805140L (sv) Bensimidazolderivat
FI783515A7 (fi) 1,2-benzisoxazoloxyaettiksyror och relaterade foereningar
FI783393A7 (fi) 2-imino-imidazolidinderivat
MC1184A1 (fr) Derives d'oxadiazolopyrimidine
NL7808011A (nl) Norbornaan- en norborneen-derivaten.
FI780028A7 (fi) Piperidinderivater
SE7804125L (sv) 3-(1-piperazinyl)-1,2,4-bensotriaziner och n-oxider
SE7801046L (sv) Azacykloalkaner, azacykloalkener och derivat derav
MC1183A1 (fr) Derives d'oxadiazolopyrimidine
NL7803725A (nl) 4-alkylthio-2-trifluormethylalkaansulfonaniliden en derivaten daarvan.