ZA782514B - 4-aminomethyl-1-(3,3,3-triarylpropyl)-4-arylpiperidine and related compounds - Google Patents
4-aminomethyl-1-(3,3,3-triarylpropyl)-4-arylpiperidine and related compoundsInfo
- Publication number
- ZA782514B ZA782514B ZA00782514A ZA782514A ZA782514B ZA 782514 B ZA782514 B ZA 782514B ZA 00782514 A ZA00782514 A ZA 00782514A ZA 782514 A ZA782514 A ZA 782514A ZA 782514 B ZA782514 B ZA 782514B
- Authority
- ZA
- South Africa
- Prior art keywords
- triarylpropyl
- arylpiperidine
- aminomethyl
- related compounds
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/18—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D211/26—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with substituted hydrocarbon radicals attached to ring carbon atoms with hydrocarbon radicals, substituted by nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/60—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
- C07D211/62—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4
- C07D211/64—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals attached in position 4 having an aryl radical as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Hydrogenated Pyridines (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/792,616 US4069223A (en) | 1977-05-02 | 1977-05-02 | 4-Aminomethyl-1-(3,3,3-triarylpropyl)-4-arylpiperidine and derivatives thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ZA782514B true ZA782514B (en) | 1979-06-27 |
Family
ID=25157505
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ZA00782514A ZA782514B (en) | 1977-05-02 | 1978-05-02 | 4-aminomethyl-1-(3,3,3-triarylpropyl)-4-arylpiperidine and related compounds |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4069223A (xx) |
| JP (1) | JPS549281A (xx) |
| AU (1) | AU520250B2 (xx) |
| CA (1) | CA1105465A (xx) |
| DE (1) | DE2819210A1 (xx) |
| FR (1) | FR2389605B1 (xx) |
| GB (1) | GB1581923A (xx) |
| NL (1) | NL7804725A (xx) |
| SE (1) | SE7805011L (xx) |
| ZA (1) | ZA782514B (xx) |
Families Citing this family (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS53125944U (xx) * | 1977-12-22 | 1978-10-06 | ||
| US4173641A (en) * | 1978-05-15 | 1979-11-06 | Pfizer Inc. | Di-O-n-alkyl glycerol derivatives as immune stimulants |
| US6190691B1 (en) | 1994-04-12 | 2001-02-20 | Adolor Corporation | Methods for treating inflammatory conditions |
| US5962477A (en) * | 1994-04-12 | 1999-10-05 | Adolor Corporation | Screening methods for cytokine inhibitors |
| US6573282B1 (en) | 1995-09-12 | 2003-06-03 | Adolor Corporation | Peripherally active anti-hyperalgesic opiates |
| US5849761A (en) * | 1995-09-12 | 1998-12-15 | Regents Of The University Of California | Peripherally active anti-hyperalgesic opiates |
| US6353004B1 (en) | 1997-07-14 | 2002-03-05 | Adolor Coporation | Peripherally acting anti-pruritic opiates |
| US5849762A (en) * | 1997-07-14 | 1998-12-15 | Adolor Corporation | Peripherally acting anti-pruritic opiates |
| US20030158220A1 (en) * | 1997-11-03 | 2003-08-21 | Foss Joseph F. | Use of methylnaltrexone and related compounds to treat chronic opioid use side effects |
| MXPA03009353A (es) * | 2001-04-12 | 2004-02-12 | Pharmacopeia Inc | Aril y biaril piperidinas utilizadas como antagonistas de mch. |
| DK2368553T3 (en) * | 2003-04-08 | 2015-02-09 | Progenics Pharm Inc | Pharmaceutical preparation comprising methylnaltrexone |
| AR057035A1 (es) * | 2005-05-25 | 2007-11-14 | Progenics Pharm Inc | SíNTESIS DE (R)-N-METILNALTREXONA, COMPOSICIONES FARMACÉUTICAS Y USOS |
| AR057325A1 (es) * | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
| EP1749528A1 (en) | 2005-08-05 | 2007-02-07 | Pharma C S.A. | Pharmaceutical combinations containing a mu opioid agonist and an inhibitor of NO production |
| TW200817048A (en) * | 2006-09-08 | 2008-04-16 | Wyeth Corp | Dry powder compound formulations and uses thereof |
| EP3064503A1 (en) * | 2007-03-29 | 2016-09-07 | Progenics Pharmaceuticals, Inc. | Peripheral opioid receptor antagonists and uses thereof |
| ES2765811T5 (es) | 2007-03-29 | 2024-02-27 | Progenics Pharm Inc | Forma cristalina de bromuro de (R)-n-metilnaltrexona y sus usos |
| PT2565195E (pt) | 2007-03-29 | 2015-07-28 | Wyeth Llc | Antagonistas e receptor opióide periférico e respectivas utilizações |
| EP2240489A1 (en) * | 2008-02-06 | 2010-10-20 | Progenics Pharmaceuticals, Inc. | Preparation and use of (r),(r)-2,2'-bis-methylnaltrexone |
| CA2676881C (en) | 2008-09-30 | 2017-04-25 | Wyeth | Peripheral opioid receptor antagonists and uses thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1125112A (en) | 1966-01-07 | 1968-08-28 | Science Union & Cie | New derivatives of diazabicyclo-decane and process for preparing them |
| US3998832A (en) * | 1975-04-16 | 1976-12-21 | G. D. Searle & Co. | Anti-diarrheal compounds |
-
1977
- 1977-05-02 US US05/792,616 patent/US4069223A/en not_active Expired - Lifetime
-
1978
- 1978-05-01 AU AU35622/78A patent/AU520250B2/en not_active Expired
- 1978-05-01 CA CA302,344A patent/CA1105465A/en not_active Expired
- 1978-05-02 DE DE19782819210 patent/DE2819210A1/de active Pending
- 1978-05-02 NL NL7804725A patent/NL7804725A/xx not_active Application Discontinuation
- 1978-05-02 GB GB17228/78A patent/GB1581923A/en not_active Expired
- 1978-05-02 ZA ZA00782514A patent/ZA782514B/xx unknown
- 1978-05-02 JP JP5324578A patent/JPS549281A/ja active Pending
- 1978-05-02 FR FR7812998A patent/FR2389605B1/fr not_active Expired
- 1978-05-02 SE SE7805011A patent/SE7805011L/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE2819210A1 (de) | 1979-02-08 |
| AU520250B2 (en) | 1982-01-21 |
| GB1581923A (en) | 1980-12-31 |
| US4069223A (en) | 1978-01-17 |
| FR2389605A1 (xx) | 1978-12-01 |
| SE7805011L (sv) | 1978-11-03 |
| AU3562278A (en) | 1979-11-08 |
| NL7804725A (nl) | 1978-11-06 |
| CA1105465A (en) | 1981-07-21 |
| JPS549281A (en) | 1979-01-24 |
| FR2389605B1 (xx) | 1981-07-17 |
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