SE7706060L - NEW 1-ARYLOXY-2,3-EPOXYPROPANES AND PROCEDURES FOR THEIR PREPARATION - Google Patents

NEW 1-ARYLOXY-2,3-EPOXYPROPANES AND PROCEDURES FOR THEIR PREPARATION

Info

Publication number
SE7706060L
SE7706060L SE7706060A SE7706060A SE7706060L SE 7706060 L SE7706060 L SE 7706060L SE 7706060 A SE7706060 A SE 7706060A SE 7706060 A SE7706060 A SE 7706060A SE 7706060 L SE7706060 L SE 7706060L
Authority
SE
Sweden
Prior art keywords
radical
aryl
lower alkyl
alkyl radical
aryloxy
Prior art date
Application number
SE7706060A
Other languages
Swedish (sv)
Inventor
U Stache
W Fritsch
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of SE7706060L publication Critical patent/SE7706060L/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/22Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D303/00Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
    • C07D303/02Compounds containing oxirane rings
    • C07D303/12Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
    • C07D303/18Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
    • C07D303/20Ethers with hydroxy compounds containing no oxirane rings
    • C07D303/24Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Epoxy Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

of the disclosure: Compounds of the formula wherein R1 and R1' are the same or different and represent hydrogen, an alkyl or alkoxy radical having 1 - 4 carbon atoms, the allyl radical, halogen or the nitro group and R2 represents an acrylic acid radical or acrylic acid nitrile radical of the formulae or wherein R3 represents hydrogen, a (C1-C5)-alkyl radical, an unsubstituted aryl or aryl lower alkyl radical or an aryl or aryl- lower alkyl radical substituted by lower alkyl or lower alkoxy, R4 represents hydrogen or a (C1-C8)-alkyl radical, and R5 represents hydrogen, a lower alkyl or aryl- lower alkyl radical and process for their manufacture. The compounds according to the invention are valuable intermediate products for the production of 1-aryloxy-2-hydroxy-3-aminopropanes that are used as medicaments for the treatment of heart diseases.
SE7706060A 1976-05-25 1977-05-24 NEW 1-ARYLOXY-2,3-EPOXYPROPANES AND PROCEDURES FOR THEIR PREPARATION SE7706060L (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19762623313 DE2623313A1 (en) 1976-05-25 1976-05-25 NEW 1-ARYLOXY-2,3-EPOXY-PROPANE AND THE METHOD OF MANUFACTURING IT

Publications (1)

Publication Number Publication Date
SE7706060L true SE7706060L (en) 1977-11-26

Family

ID=5978906

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7706060A SE7706060L (en) 1976-05-25 1977-05-24 NEW 1-ARYLOXY-2,3-EPOXYPROPANES AND PROCEDURES FOR THEIR PREPARATION

Country Status (17)

Country Link
JP (1) JPS5312838A (en)
AT (1) AT356125B (en)
AU (1) AU2543577A (en)
BE (1) BE855040A (en)
CA (1) CA1105041A (en)
DE (1) DE2623313A1 (en)
DK (1) DK227077A (en)
ES (1) ES458958A1 (en)
FI (1) FI771631A (en)
FR (1) FR2352811A1 (en)
HU (1) HU177844B (en)
IL (1) IL52149A0 (en)
IT (1) IT1077192B (en)
LU (1) LU77390A1 (en)
NL (1) NL7705581A (en)
SE (1) SE7706060L (en)
ZA (1) ZA773119B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS60130580A (en) * 1983-12-15 1985-07-12 Kanegafuchi Chem Ind Co Ltd Novel glycidyl compound and its production

Also Published As

Publication number Publication date
AU2543577A (en) 1978-11-30
ES458958A1 (en) 1978-02-16
AT356125B (en) 1980-04-10
DK227077A (en) 1977-11-26
FI771631A (en) 1977-11-26
NL7705581A (en) 1977-11-29
BE855040A (en) 1977-11-25
FR2352811A1 (en) 1977-12-23
ATA369877A (en) 1979-09-15
HU177844B (en) 1981-12-28
CA1105041A (en) 1981-07-14
IL52149A0 (en) 1977-07-31
LU77390A1 (en) 1977-12-22
JPS5312838A (en) 1978-02-04
ZA773119B (en) 1978-04-26
IT1077192B (en) 1985-05-04
DE2623313A1 (en) 1977-12-15

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