ES458958A1 - Production of novel 11 aryloxyy2*33epoxyypropane - Google Patents
Production of novel 11 aryloxyy2*33epoxyypropaneInfo
- Publication number
- ES458958A1 ES458958A1 ES458958A ES458958A ES458958A1 ES 458958 A1 ES458958 A1 ES 458958A1 ES 458958 A ES458958 A ES 458958A ES 458958 A ES458958 A ES 458958A ES 458958 A1 ES458958 A1 ES 458958A1
- Authority
- ES
- Spain
- Prior art keywords
- alkyl
- aryloxyy2
- novel
- production
- aryl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/22—Ethers with hydroxy compounds containing no oxirane rings with monohydroxy compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C255/00—Carboxylic acid nitriles
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D303/00—Compounds containing three-membered rings having one oxygen atom as the only ring hetero atom
- C07D303/02—Compounds containing oxirane rings
- C07D303/12—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms
- C07D303/18—Compounds containing oxirane rings with hydrocarbon radicals, substituted by singly or doubly bound oxygen atoms by etherified hydroxyl radicals
- C07D303/20—Ethers with hydroxy compounds containing no oxirane rings
- C07D303/24—Ethers with hydroxy compounds containing no oxirane rings with polyhydroxy compounds
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Epoxy Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
New 1-phenoxy-2,3-epoxy-propane derivs. are of formula (I) (where R1, R1' are each H, 1-4c alkyl, 1-4C alkoxy, allyl, halo or nitro, and R2 is -CR3= CR4-COOR5 or -CR3=CR4-CN R3 is H, 1-5C alkyl, aryl or aralkyl opt. substd. by lower alkyl or alkoxy gps. R4 is H or 1-8C alkyl and R5 is H alkyl or aryl-lower alkyl). (I) are intermediates for 1-aryloxy-2-hydroxy-3-aminopropanes used for the treatment of cardiac disorders. Typical (I) is dl-3-(2-(2,3-oxidopropoxy)-phenyl)-crotononitrile.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19762623313 DE2623313A1 (en) | 1976-05-25 | 1976-05-25 | NEW 1-ARYLOXY-2,3-EPOXY-PROPANE AND THE METHOD OF MANUFACTURING IT |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES458958A1 true ES458958A1 (en) | 1978-02-16 |
Family
ID=5978906
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES458958A Expired ES458958A1 (en) | 1976-05-25 | 1977-05-19 | Production of novel 11 aryloxyy2*33epoxyypropane |
Country Status (17)
| Country | Link |
|---|---|
| JP (1) | JPS5312838A (en) |
| AT (1) | AT356125B (en) |
| AU (1) | AU2543577A (en) |
| BE (1) | BE855040A (en) |
| CA (1) | CA1105041A (en) |
| DE (1) | DE2623313A1 (en) |
| DK (1) | DK227077A (en) |
| ES (1) | ES458958A1 (en) |
| FI (1) | FI771631A (en) |
| FR (1) | FR2352811A1 (en) |
| HU (1) | HU177844B (en) |
| IL (1) | IL52149A0 (en) |
| IT (1) | IT1077192B (en) |
| LU (1) | LU77390A1 (en) |
| NL (1) | NL7705581A (en) |
| SE (1) | SE7706060L (en) |
| ZA (1) | ZA773119B (en) |
Families Citing this family (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS60130580A (en) * | 1983-12-15 | 1985-07-12 | Kanegafuchi Chem Ind Co Ltd | Novel glycidyl compound and its production |
-
1976
- 1976-05-25 DE DE19762623313 patent/DE2623313A1/en active Pending
-
1977
- 1977-05-19 ES ES458958A patent/ES458958A1/en not_active Expired
- 1977-05-20 NL NL7705581A patent/NL7705581A/en not_active Application Discontinuation
- 1977-05-23 FI FI771631A patent/FI771631A/fi not_active Application Discontinuation
- 1977-05-23 IT IT23891/77A patent/IT1077192B/en active
- 1977-05-23 LU LU77390A patent/LU77390A1/xx unknown
- 1977-05-24 DK DK227077A patent/DK227077A/en not_active Application Discontinuation
- 1977-05-24 ZA ZA00773119A patent/ZA773119B/en unknown
- 1977-05-24 AT AT369877A patent/AT356125B/en not_active IP Right Cessation
- 1977-05-24 CA CA279,071A patent/CA1105041A/en not_active Expired
- 1977-05-24 HU HU77HO1986A patent/HU177844B/en unknown
- 1977-05-24 IL IL52149A patent/IL52149A0/en unknown
- 1977-05-24 AU AU25435/77A patent/AU2543577A/en not_active Expired
- 1977-05-24 SE SE7706060A patent/SE7706060L/en not_active Application Discontinuation
- 1977-05-25 FR FR7715887A patent/FR2352811A1/en not_active Withdrawn
- 1977-05-25 BE BE177908A patent/BE855040A/en unknown
- 1977-05-25 JP JP6000377A patent/JPS5312838A/en active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| AU2543577A (en) | 1978-11-30 |
| AT356125B (en) | 1980-04-10 |
| DK227077A (en) | 1977-11-26 |
| FI771631A (en) | 1977-11-26 |
| NL7705581A (en) | 1977-11-29 |
| BE855040A (en) | 1977-11-25 |
| FR2352811A1 (en) | 1977-12-23 |
| ATA369877A (en) | 1979-09-15 |
| HU177844B (en) | 1981-12-28 |
| CA1105041A (en) | 1981-07-14 |
| IL52149A0 (en) | 1977-07-31 |
| SE7706060L (en) | 1977-11-26 |
| LU77390A1 (en) | 1977-12-22 |
| JPS5312838A (en) | 1978-02-04 |
| ZA773119B (en) | 1978-04-26 |
| IT1077192B (en) | 1985-05-04 |
| DE2623313A1 (en) | 1977-12-15 |
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