SE7610171L - WAY TO PRODUCE NEW AMINOIMIDAZOLE-ISOKINOLINE DERIVATIVES - Google Patents

WAY TO PRODUCE NEW AMINOIMIDAZOLE-ISOKINOLINE DERIVATIVES

Info

Publication number
SE7610171L
SE7610171L SE7610171A SE7610171A SE7610171L SE 7610171 L SE7610171 L SE 7610171L SE 7610171 A SE7610171 A SE 7610171A SE 7610171 A SE7610171 A SE 7610171A SE 7610171 L SE7610171 L SE 7610171L
Authority
SE
Sweden
Prior art keywords
derivatives
denotes
alkyl
aralkyl
isokinoline
Prior art date
Application number
SE7610171A
Other languages
Swedish (sv)
Other versions
SE410190B (en
Inventor
K Takacs
L Szekeres
K Harsanyi
G Papp
A Neszmelyi
E Benedek
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of SE7610171L publication Critical patent/SE7610171L/en
Publication of SE410190B publication Critical patent/SE410190B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/08Vasodilators for multiple indications
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J23/00Details of transit-time tubes of the types covered by group H01J25/00
    • H01J23/02Electrodes; Magnetic control means; Screens
    • HELECTRICITY
    • H01ELECTRIC ELEMENTS
    • H01JELECTRIC DISCHARGE TUBES OR DISCHARGE LAMPS
    • H01J25/00Transit-time tubes, e.g. klystrons, travelling-wave tubes, magnetrons
    • H01J25/34Travelling-wave tubes; Tubes in which a travelling wave is simulated at spaced gaps

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Cardiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Urology & Nephrology (AREA)
  • Vascular Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Microwave Tubes (AREA)

Abstract

The novel aminopyrazoloisoquinoline derivatives of the formula <IMAGE> in which A denotes an alkoxy group containing 1 to 4 carbon atoms and D denotes hydrogen, acyl, alkyl or aralkyl, have a favourable effect on the activity of the heart. They are prepared by treating compounds of the general formula <IMAGE> in which A has the above meaning and R denotes an alkyl, aralkyl or aryl group, with a strong alkaline solution. Compounds of the formula I are thus obtained, in which D denotes hydrogen which can be replaced by an acyl group. This hydrogen can also be replaced by an alkyl or aralkyl group by reaction with an aldehyde or ketone and subsequent reduction of the resulting intermediate.
SE7610171A 1972-06-30 1976-09-14 METHOD OF PREPARING AMINOPYRAZOLO (5.1-A) ISOKINOLIN DERIVATIVES SE410190B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HUCI1248A HU167240B (en) 1972-06-30 1972-06-30

Publications (2)

Publication Number Publication Date
SE7610171L true SE7610171L (en) 1976-09-14
SE410190B SE410190B (en) 1979-10-01

Family

ID=10994443

Family Applications (6)

Application Number Title Priority Date Filing Date
SE7308998A SE405603B (en) 1972-06-30 1973-06-26 METHOD OF PRODUCING 3-AMINO-IMIDAZO (5.1-A) ISOKINOLINE DERIVATIVES
SE7610170A SE425314B (en) 1972-06-30 1976-09-14 SET TO PREPARE 2-AMINO-PYRAZOLO / 5, 1-A / ISOQINOLINE DERIVATIVES
SE7610171A SE410190B (en) 1972-06-30 1976-09-14 METHOD OF PREPARING AMINOPYRAZOLO (5.1-A) ISOKINOLIN DERIVATIVES
SE7610169A SE410189B (en) 1972-06-30 1976-09-14 METHOD OF PRODUCING 3-AMINO-IMIDAZO (5.1-A) ISOKINOLINE DERIVATIVES
SE8000253A SE431455B (en) 1972-06-30 1980-01-11 SET TO MAKE AMINOIMIDAZOISOKINOLIN DERIVATIVES
SE8002538A SE420968B (en) 1972-06-30 1980-04-02 PROVIDED TO COMPENSATE THE HARMFUL INCREASE OF THE CATHODE DRUM DURING THE STARTING PERIOD OF A WALKING WAGON

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SE7308998A SE405603B (en) 1972-06-30 1973-06-26 METHOD OF PRODUCING 3-AMINO-IMIDAZO (5.1-A) ISOKINOLINE DERIVATIVES
SE7610170A SE425314B (en) 1972-06-30 1976-09-14 SET TO PREPARE 2-AMINO-PYRAZOLO / 5, 1-A / ISOQINOLINE DERIVATIVES

Family Applications After (3)

Application Number Title Priority Date Filing Date
SE7610169A SE410189B (en) 1972-06-30 1976-09-14 METHOD OF PRODUCING 3-AMINO-IMIDAZO (5.1-A) ISOKINOLINE DERIVATIVES
SE8000253A SE431455B (en) 1972-06-30 1980-01-11 SET TO MAKE AMINOIMIDAZOISOKINOLIN DERIVATIVES
SE8002538A SE420968B (en) 1972-06-30 1980-04-02 PROVIDED TO COMPENSATE THE HARMFUL INCREASE OF THE CATHODE DRUM DURING THE STARTING PERIOD OF A WALKING WAGON

Country Status (24)

Country Link
JP (2) JPS5336480B2 (en)
AR (5) AR208055A1 (en)
AT (1) AT329058B (en)
BE (1) BE801668A (en)
CA (1) CA1014559A (en)
CH (6) CH602731A5 (en)
CS (1) CS179024B1 (en)
DD (1) DD108090A1 (en)
DE (1) DE2332860C2 (en)
DK (1) DK141066B (en)
EG (1) EG11302A (en)
ES (1) ES416971A1 (en)
FI (1) FI55199C (en)
FR (1) FR2190458B1 (en)
GB (1) GB1438819A (en)
HU (1) HU167240B (en)
IL (1) IL42613A (en)
IN (1) IN139710B (en)
NL (1) NL177750C (en)
NO (1) NO138908C (en)
PL (6) PL94060B1 (en)
SE (6) SE405603B (en)
SU (5) SU584782A3 (en)
YU (4) YU36175B (en)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH603643A5 (en) * 1976-09-29 1978-08-31 Sandoz Ag
HU176214B (en) * 1977-05-18 1981-01-28 Chinoin Gyogyszer Es Vegyeszet Process for producing new 5,6-dihydro-imidazo-square bracket-5,1-a-square bracket closed-isoquinolin derivatives
MXPA01011860A (en) * 1999-05-19 2002-05-06 Procter & Gamble Imidazo-containing heterocyclic compounds, their compositions and uses.
US6552033B1 (en) 2000-05-16 2003-04-22 The Procter & Gamble Co. Imidazo-containing heterocyclic compounds, their compositions and uses
PL2573073T3 (en) * 2011-09-26 2015-04-30 Sanofi Sa Pyrazoloquinolinone derivatives, preparation thereof and therapeutic use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH25A (en) * 1888-11-16 1889-04-05 Saurer & Soehne F Machine for threading needles and for tying threads

Also Published As

Publication number Publication date
ATA563773A (en) 1975-07-15
SE7308998L (en) 1973-12-31
PL96818B1 (en) 1978-01-31
JPS4942697A (en) 1974-04-22
SE405603B (en) 1978-12-18
CH603639A5 (en) 1978-08-31
YU179673A (en) 1981-06-30
NL7309104A (en) 1974-01-02
YU299579A (en) 1981-06-30
SE420968B (en) 1981-11-09
SU584782A3 (en) 1977-12-15
CS179024B1 (en) 1977-10-31
DE2332860C2 (en) 1982-12-02
YU36300B (en) 1982-06-18
IN139710B (en) 1976-07-24
PL97544B1 (en) 1978-03-30
CA1014559A (en) 1977-07-26
SE8002538L (en) 1981-10-03
FI55199B (en) 1979-02-28
SE425314B (en) 1982-09-20
CH602731A5 (en) 1978-07-31
PL94060B1 (en) 1977-07-30
SE431455B (en) 1984-02-06
SU584783A3 (en) 1977-12-15
IL42613A0 (en) 1973-08-29
YU299479A (en) 1981-08-31
IL42613A (en) 1977-05-31
SU591148A3 (en) 1978-01-30
JPS5740152B2 (en) 1982-08-25
SU587863A3 (en) 1978-01-05
FR2190458B1 (en) 1977-04-15
SU596170A3 (en) 1978-02-28
PL94059B1 (en) 1977-07-30
JPS5334799A (en) 1978-03-31
ES416971A1 (en) 1976-02-16
CH602729A5 (en) 1978-07-31
GB1438819A (en) 1976-06-09
EG11302A (en) 1978-06-30
AR209330A1 (en) 1977-04-15
AT329058B (en) 1976-04-26
FR2190458A1 (en) 1974-02-01
DK141066C (en) 1980-06-30
SE410190B (en) 1979-10-01
NO138908B (en) 1978-08-28
PL94046B1 (en) 1977-07-30
NO138908C (en) 1978-12-06
CH610900A5 (en) 1979-05-15
FI55199C (en) 1979-06-11
JPS5336480B2 (en) 1978-10-03
SE7610170L (en) 1976-09-14
BE801668A (en) 1973-10-15
HU167240B (en) 1975-09-27
CH603647A5 (en) 1978-08-31
DD108090A1 (en) 1974-09-05
DK141066B (en) 1980-01-07
CH602730A5 (en) 1978-07-31
SE410189B (en) 1979-10-01
DE2332860A1 (en) 1974-03-07
AR211857A1 (en) 1978-03-31
NL177750C (en) 1985-11-18
AR209331A1 (en) 1977-04-15
AR210066A1 (en) 1977-06-30
YU36177B (en) 1982-02-25
PL93702B1 (en) 1977-06-30
YU36175B (en) 1982-02-25
YU36176B (en) 1982-02-25
AR208055A1 (en) 1976-11-30
YU299679A (en) 1981-06-30
SE7610169L (en) 1976-09-14
NL177750B (en) 1985-06-17

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