SE7607157L - Substituerad bensofuran-2-karboxylsyra - Google Patents

Substituerad bensofuran-2-karboxylsyra

Info

Publication number
SE7607157L
SE7607157L SE7607157A SE7607157A SE7607157L SE 7607157 L SE7607157 L SE 7607157L SE 7607157 A SE7607157 A SE 7607157A SE 7607157 A SE7607157 A SE 7607157A SE 7607157 L SE7607157 L SE 7607157L
Authority
SE
Sweden
Prior art keywords
carboxylic acid
substituted benzofuran
benzofuran
antikaluretic
saluretic
Prior art date
Application number
SE7607157A
Other languages
English (en)
Swedish (sv)
Inventor
Jr E J Cragoe
Jr O W Woltersdorf
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SE7607157L publication Critical patent/SE7607157L/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/82—Benzo [b] furans; Hydrogenated benzo [b] furans with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/84—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D307/85—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/10—Antioedematous agents; Diuretics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • C07D307/80—Radicals substituted by oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Cardiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7607157A 1975-07-09 1976-06-22 Substituerad bensofuran-2-karboxylsyra SE7607157L (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US59483975A 1975-07-09 1975-07-09

Publications (1)

Publication Number Publication Date
SE7607157L true SE7607157L (sv) 1977-01-10

Family

ID=24380621

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7607157A SE7607157L (sv) 1975-07-09 1976-06-22 Substituerad bensofuran-2-karboxylsyra

Country Status (14)

Country Link
US (2) US4087542A (nl)
JP (1) JPS5210261A (nl)
AU (1) AU505135B2 (nl)
BE (1) BE843644A (nl)
CH (1) CH624949A5 (nl)
DE (1) DE2630800A1 (nl)
DK (1) DK282076A (nl)
ES (1) ES449389A1 (nl)
FR (1) FR2316934A1 (nl)
GB (1) GB1511427A (nl)
HU (1) HU176564B (nl)
NL (1) NL7606908A (nl)
SE (1) SE7607157L (nl)
ZA (1) ZA764080B (nl)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4100294A (en) 1976-12-06 1978-07-11 Merck & Co., Inc. 5-(Hydroxy (substituted) methyl)-2,3-dihydrobenzo furan-2-carboxylic acid and its derivatives
US4205080A (en) * 1977-07-21 1980-05-27 Shell Oil Company 2,3-Dihydro benzofuran carboxamides
US4189496A (en) * 1978-02-16 1980-02-19 Merck & Co., Inc. 2,3-Dihydro-5-thienylmethyl and furylmethyl-6-substituted and 6,7-disubstituted-benzofuran-2-carboxylic acid
EP0019955A1 (en) * 1979-05-16 1980-12-10 Shell Internationale Researchmaatschappij B.V. Benzofurancarboxylic acid derivatives, their preparation and their inclusion in lipogenesis inhibiting compositions
US4237144A (en) * 1979-06-21 1980-12-02 Merck & Co., Inc. 2,3-Dihydro-2,6,7-trisubstituted-5-acylbenzofurans
US4237130A (en) * 1979-06-21 1980-12-02 Merck & Co., Inc. 2,3-Dihydro-6,7-disubstituted-5-(substituted sulfonyl)benzofuran-2-carboxylic acids
JPS5737737A (en) * 1980-08-15 1982-03-02 Fuji Photo Film Co Ltd Magnetic recording medium
US4510322A (en) * 1981-07-13 1985-04-09 Merck & Co., Inc. Indacrinone having enhanced uricosuric
NZ200641A (en) * 1981-07-13 1985-12-13 Merck & Co Inc Pharmaceutical compositions containing(+)and(-)enantiomers of indacrinone
US4435422A (en) * 1982-09-15 1984-03-06 Abbott Laboratories 5-Substituted 2,3-dihydrobenzofuran-2-carboxylic acids and their use in diuretic compositions
JPS5973579A (ja) * 1982-10-19 1984-04-25 Kotobuki Seiyaku Kk ベンゾフラン又はベンゾチオフェン誘導体，この化合物を有効成分とする尿酸排泄剤及びその製造方法
DE3460315D1 (en) * 1983-02-19 1986-08-28 Beecham Group Plc Benzofuran and benzothiophene-carboxylic-acid derivatives
US4578509A (en) * 1983-04-01 1986-03-25 Merck & Co., Inc. Process for preparing a manipulated enantiomer mixture by asymmetric chiral phase transfer catalysis
DE3317884A1 (de) * 1983-05-17 1984-11-22 Hoechst Ag, 6230 Frankfurt 5-(4-chlor-3-sulfamoylbenzoyl)-2,3-dihydro-2-benzofurancarbonsaeuren und verfahren zu ihrer herstellung
US4654365A (en) * 1985-09-26 1987-03-31 Merck & Co., Inc. 2,3-dihydro-5-(3-oxo-2-cyclohexen-1-yl)-2-benzofurancarboxylic acids, and their salts useful in the treatment of brain injury
US6858615B2 (en) * 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenyl guanidine sodium channel blockers
US6858614B2 (en) * 2002-02-19 2005-02-22 Parion Sciences, Inc. Phenolic guanidine sodium channel blockers
US6903105B2 (en) * 2003-02-19 2005-06-07 Parion Sciences, Inc. Sodium channel blockers
US20050090505A1 (en) * 2003-08-18 2005-04-28 Johnson Michael R. Methods of reducing risk of infection from pathogens
US7745442B2 (en) 2003-08-20 2010-06-29 Parion Sciences, Inc. Methods of reducing risk of infection from pathogens
AR086745A1 (es) 2011-06-27 2014-01-22 Parion Sciences Inc 3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
KR20150095870A (ko) 2012-12-17 2015-08-21 패리온 사이언스 인코퍼레이티드 3,5-디아미노-6-클로로-n-(n-(4-페닐부틸)카르밤이미도일)피라진-2-카르복스아미드 화합물
AU2013363218B2 (en) 2012-12-17 2018-03-15 Parion Sciences, Inc. Chloro-pyrazine carboxamide derivatives useful for the treatment of diseases favoured by insufficient mucosal hydration
US9102633B2 (en) 2013-12-13 2015-08-11 Parion Sciences, Inc. Arylalkyl- and aryloxyalkyl-substituted epithelial sodium channel blocking compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH508615A (de) * 1968-05-30 1971-06-15 Ciba Geigy Ag Verfahren zur Herstellung von neuen heterocyclischen Carbonsäuren
FR2201883B1 (nl) * 1972-10-05 1975-10-31 Roussel Uclaf

Also Published As

Publication number Publication date
US4087542A (en) 1978-05-02
US4163794A (en) 1979-08-07
GB1511427A (en) 1978-05-17
ZA764080B (en) 1978-02-22
DK282076A (da) 1977-01-10
JPS5210261A (en) 1977-01-26
ES449389A1 (es) 1977-12-16
NL7606908A (nl) 1977-01-11
AU1540476A (en) 1978-01-05
AU505135B2 (en) 1979-11-08
FR2316934B1 (nl) 1979-07-20
FR2316934A1 (fr) 1977-02-04
CH624949A5 (nl) 1981-08-31
HU176564B (en) 1981-03-28
DE2630800A1 (de) 1977-01-27
BE843644A (fr) 1976-12-30

Similar Documents

Publication Publication Date Title
SE7607157L (sv) Substituerad bensofuran-2-karboxylsyra
NO780151L (no) Fremgangsmaate for fremstilling av fysiologisk aktive acylderivater av aminosyrer
IT7825415A0 (it) Derivati di acidi fenossi-fenil-tip-alcan-carbossilici, procedimento per la loro preparazione e loro impiego.
IT7825083A0 (it) Derivati di acidi piridilossi-fenossi-alcancarbossili ci, procedimento per la loro preparazione e loro impiego.
BE848712A (fr) Compositions d'acides carboxyliques,
SE7601422L (sv) 6-oxo-7-substituerade och 7,7-disubstituerad-6h-indeno-(5,4-b)furan(och tiofen)-karboxylsyror
IT1109095B (it) Acidi 1.3 ditietan 2 carbossilici e procedimento per la loro preparazione
FR2301253A1 (fr) Derives de la
BE845308A (fr) Derives d'acides phenoxy-alkylcarboxyliques
AR217240A1 (es) Procedimiento para preparar derivados acilamino sustituidos de 1,2,4-oxadiazol,1,3-4-oxadiazol,1,2,4-tiadiazol y 1,3,4-tiadiazol,terapeuticamente utiles
IT7821871A0 (it) Procedimento per la preparazione di nuovi acidi fosfinici e di loro derivati e anche loro impiego.
FR2332747A1 (fr) Derives d'a-aminocetones
AR215851A1 (es) Procedimiento para la preparacion de 12,13-desepoxi-12,13-dehidrorosaramicina y derivados de la misma
FR2322604A1 (fr) Derives 3-triazolylthio d'ureido-7a-methoxy-ou demethoxycephalosporines
FR2321488A1 (fr) Derives d'acides aminoalcane sulfoniques, leur obtention et leur application
FR2313074A1 (fr) Diastereoisomeres de derives phenylaminoethanol
BE830880A (fr) Derives de la benzoyl n',n'-di(n-propyl)-dl-isoglutamine posedant une activite antiarthrosique et anti-inflammatoire
SE422796B (sv) Forfarande for framstellning av 6,11-dihydro-11-oxo-dibens (b,e)-oxepin-alkankarboxylsyror
AR209172A1 (es) Procedimiento para la fabricacion de 9alfa 11alfa 15-trihidroxi-15-cicloalquil-16,17,18,19,20-pentanor-prostanoico y el ester metilico
SE7605518L (sv) Forfarande for framstellning av 3,5-bisoxygenerade 2-(omega-halogen-3-oxygenerad-l-alkenyl)cyklopentan-l-heptansyror och derivat derav
IT1094614B (it) Derivati di acidi azolil-alcan-carbossilici,procedimento per la loro preparazione e loro impiego come funghicidi
FR2345152A1 (fr) Nouveaux derives 4-substitues d'acides et d'esters pyrazolo-(1,5-a)quinoxaline-3-carboxyliques
BE846657A (fr) 2,4,6-triiodo-anilides 3,5-disubstitues d'acides polyhydroxy-monobasiques
AR212174A1 (es) Procedimiento para la preparacion de derivados de las 1-aminometil-6,7-dihidroxi-1,2,3,4-tetrahidroisoquinoleinas
BE849389A (fr) Sels de derives du 2,4-diaminoazobenzene et d'acides alkylarene-sulfoniques, leur preparation et leur utilisation comme colorants

Legal Events

Date Code Title Description
NAV Patent application has lapsed

Ref document number: 7607157-0

Format of ref document f/p: F