SE522979C2 - Sårförband innefattande en icke-enzymatisk antioxidant - Google Patents
Sårförband innefattande en icke-enzymatisk antioxidantInfo
- Publication number
- SE522979C2 SE522979C2 SE0202081A SE0202081A SE522979C2 SE 522979 C2 SE522979 C2 SE 522979C2 SE 0202081 A SE0202081 A SE 0202081A SE 0202081 A SE0202081 A SE 0202081A SE 522979 C2 SE522979 C2 SE 522979C2
- Authority
- SE
- Sweden
- Prior art keywords
- wound
- glutathione
- wound dressing
- leukocytes
- acetylcysteine
- Prior art date
Links
- 239000003963 antioxidant agent Substances 0.000 title claims abstract description 13
- 230000002255 enzymatic effect Effects 0.000 title claims abstract description 13
- 230000003078 antioxidant effect Effects 0.000 title claims abstract description 9
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 claims abstract description 38
- 108010024636 Glutathione Proteins 0.000 claims abstract description 19
- 229960003180 glutathione Drugs 0.000 claims abstract description 19
- PWKSKIMOESPYIA-BYPYZUCNSA-N L-N-acetyl-Cysteine Chemical compound CC(=O)N[C@@H](CS)C(O)=O PWKSKIMOESPYIA-BYPYZUCNSA-N 0.000 claims abstract description 12
- 229960004308 acetylcysteine Drugs 0.000 claims abstract description 12
- 150000003573 thiols Chemical class 0.000 claims description 8
- 239000006261 foam material Substances 0.000 claims description 3
- 230000002209 hydrophobic effect Effects 0.000 claims description 3
- 239000000017 hydrogel Substances 0.000 claims description 2
- 210000000265 leukocyte Anatomy 0.000 description 21
- 229920000742 Cotton Polymers 0.000 description 20
- 230000004913 activation Effects 0.000 description 11
- 239000000654 additive Substances 0.000 description 8
- 210000004027 cell Anatomy 0.000 description 7
- 239000000853 adhesive Substances 0.000 description 6
- 230000001070 adhesive effect Effects 0.000 description 6
- 239000000499 gel Substances 0.000 description 6
- 229910052760 oxygen Inorganic materials 0.000 description 6
- 239000001301 oxygen Substances 0.000 description 6
- 102000004190 Enzymes Human genes 0.000 description 5
- 108090000790 Enzymes Proteins 0.000 description 5
- 230000003859 lipid peroxidation Effects 0.000 description 5
- 241000894006 Bacteria Species 0.000 description 4
- 229920000392 Zymosan Polymers 0.000 description 4
- 239000000243 solution Substances 0.000 description 4
- 239000000126 substance Substances 0.000 description 4
- 102000016938 Catalase Human genes 0.000 description 3
- 108010053835 Catalase Proteins 0.000 description 3
- 102000019197 Superoxide Dismutase Human genes 0.000 description 3
- 108010012715 Superoxide dismutase Proteins 0.000 description 3
- 230000000844 anti-bacterial effect Effects 0.000 description 3
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 3
- 210000000170 cell membrane Anatomy 0.000 description 3
- 229920002678 cellulose Polymers 0.000 description 3
- 239000001913 cellulose Substances 0.000 description 3
- 239000011248 coating agent Substances 0.000 description 3
- 238000000576 coating method Methods 0.000 description 3
- 230000002745 absorbent Effects 0.000 description 2
- 239000002250 absorbent Substances 0.000 description 2
- -1 cyanoborohydride Chemical compound 0.000 description 2
- 230000000694 effects Effects 0.000 description 2
- 238000005259 measurement Methods 0.000 description 2
- 239000012528 membrane Substances 0.000 description 2
- KHIWWQKSHDUIBK-UHFFFAOYSA-N periodic acid Chemical compound OI(=O)(=O)=O KHIWWQKSHDUIBK-UHFFFAOYSA-N 0.000 description 2
- 239000004033 plastic Substances 0.000 description 2
- NIXOWILDQLNWCW-UHFFFAOYSA-M Acrylate Chemical compound [O-]C(=O)C=C NIXOWILDQLNWCW-UHFFFAOYSA-M 0.000 description 1
- 241000191967 Staphylococcus aureus Species 0.000 description 1
- 230000001580 bacterial effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 239000006161 blood agar Substances 0.000 description 1
- 239000003795 chemical substances by application Substances 0.000 description 1
- 238000001378 electrochemiluminescence detection Methods 0.000 description 1
- 210000000416 exudates and transudate Anatomy 0.000 description 1
- 239000007850 fluorescent dye Substances 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- HWYHZTIRURJOHG-UHFFFAOYSA-N luminol Chemical compound O=C1NNC(=O)C2=C1C(N)=CC=C2 HWYHZTIRURJOHG-UHFFFAOYSA-N 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 230000000813 microbial effect Effects 0.000 description 1
- 150000002978 peroxides Chemical class 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 238000007039 two-step reaction Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/20—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons containing organic materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L15/00—Chemical aspects of, or use of materials for, bandages, dressings or absorbent pads
- A61L15/16—Bandages, dressings or absorbent pads for physiological fluids such as urine or blood, e.g. sanitary towels, tampons
- A61L15/42—Use of materials characterised by their function or physical properties
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Hematology (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Priority Applications (13)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0202081A SE522979C2 (sv) | 2002-07-03 | 2002-07-03 | Sårförband innefattande en icke-enzymatisk antioxidant |
| PL03372831A PL372831A1 (en) | 2002-07-03 | 2003-06-27 | Wound bandage comprising a non-enzymatic antioxidant |
| CNA038146207A CN101389362A (zh) | 2002-07-03 | 2003-06-27 | 包含非酶促抗氧化剂的伤口绷带 |
| CA002488709A CA2488709A1 (en) | 2002-07-03 | 2003-06-27 | Wound bandage comprising a non-enzymatic antioxidant |
| BR0312369-3A BR0312369A (pt) | 2002-07-03 | 2003-06-27 | Bandagem para ferimento compreendendo um antioxidante não enzimático |
| US10/519,622 US20050287192A1 (en) | 2002-07-03 | 2003-06-27 | Wound bandage comprising a non-enzymatic antioxidant |
| MXPA04011934A MXPA04011934A (es) | 2002-07-03 | 2003-06-27 | VENDAJE PARA HERIDAS, QUE COMPRENDEN UN ANTIOXIDANTE NO ENZIMáTICO. |
| JP2004519447A JP2006508706A (ja) | 2002-07-03 | 2003-06-27 | 非酵素的酸化防止剤を含む創傷包帯 |
| AU2003237753A AU2003237753A1 (en) | 2002-07-03 | 2003-06-27 | Wound bandage comprising a non-enzymatic antioxidant |
| PCT/SE2003/001131 WO2004004792A2 (en) | 2002-07-03 | 2003-06-27 | Wound bandage comprising a non-enzymatic antioxidant |
| EP03736412A EP1572255A2 (de) | 2002-07-03 | 2003-06-27 | Wundverband mit einem nichtenzymatischen antioxidans |
| RU2005102595/15A RU2005102595A (ru) | 2002-07-03 | 2003-06-27 | Повязка для ран, включающая неферментативный антиоксидант |
| ZA200409444A ZA200409444B (en) | 2002-07-03 | 2004-11-23 | Wound bandage comprising a non-enzymatic antioxidant. |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE0202081A SE522979C2 (sv) | 2002-07-03 | 2002-07-03 | Sårförband innefattande en icke-enzymatisk antioxidant |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE0202081D0 SE0202081D0 (sv) | 2002-07-03 |
| SE0202081L SE0202081L (sv) | 2004-01-04 |
| SE522979C2 true SE522979C2 (sv) | 2004-03-23 |
Family
ID=20288423
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE0202081A SE522979C2 (sv) | 2002-07-03 | 2002-07-03 | Sårförband innefattande en icke-enzymatisk antioxidant |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US20050287192A1 (de) |
| EP (1) | EP1572255A2 (de) |
| JP (1) | JP2006508706A (de) |
| CN (1) | CN101389362A (de) |
| AU (1) | AU2003237753A1 (de) |
| BR (1) | BR0312369A (de) |
| CA (1) | CA2488709A1 (de) |
| MX (1) | MXPA04011934A (de) |
| PL (1) | PL372831A1 (de) |
| RU (1) | RU2005102595A (de) |
| SE (1) | SE522979C2 (de) |
| WO (1) | WO2004004792A2 (de) |
| ZA (1) | ZA200409444B (de) |
Families Citing this family (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2011502535A (ja) | 2007-11-14 | 2011-01-27 | 日立化成工業株式会社 | 末梢血白血球における、Ｆｃ受容体を介した腫瘍壊死因子スーパーファミリーｍＲＮＡ発現 |
| US11998432B2 (en) | 2016-06-30 | 2024-06-04 | Kimberly-Clark Worldwide, Inc. | Method of manufacturing a foam and fiber composite |
| CN108836633A (zh) * | 2018-05-03 | 2018-11-20 | 郑岩 | 一种基于多种高分子材料组成的复合膜结构（薄片）供氧的伤口敷料及其生产工艺 |
| GB2592911B (en) * | 2020-02-28 | 2023-06-28 | Aga Nanotech Ltd | A plasma-activatable wound dressing for treatment of infections |
| WO2025260206A1 (zh) * | 2024-06-17 | 2025-12-26 | 赵彦棕 | 一种抑菌抗炎高性能水凝胶及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5562917A (en) * | 1994-12-23 | 1996-10-08 | Pentech Pharmaceuticals, Inc. | Transdermal administration of apomorphine |
| EP0966196A4 (de) * | 1995-12-15 | 2002-03-27 | Virodene Pharmaceutical Holdin | Zusammensetzung zur organ-kryokonservierung und behandlung von viralen und bakteriellen infektionen |
| US5976117A (en) * | 1996-09-25 | 1999-11-02 | 3M Innovative Properties Company | Wound dressing |
| GB2320431B (en) * | 1996-12-20 | 2000-08-30 | Johnson & Johnson Medical | Compositions for the treatment of chronic wounds |
| DE60038100T2 (de) * | 1999-02-26 | 2009-02-12 | Johnson & Johnson Consumer Companies, Inc. | Bioadhäsive antibakterielle wundheilungszusammensetzungen |
| US7687681B2 (en) * | 2000-05-26 | 2010-03-30 | Kimberly-Clark Worldwide, Inc. | Menses specific absorbent systems |
-
2002
- 2002-07-03 SE SE0202081A patent/SE522979C2/sv not_active IP Right Cessation
-
2003
- 2003-06-27 AU AU2003237753A patent/AU2003237753A1/en not_active Abandoned
- 2003-06-27 WO PCT/SE2003/001131 patent/WO2004004792A2/en not_active Ceased
- 2003-06-27 MX MXPA04011934A patent/MXPA04011934A/es unknown
- 2003-06-27 JP JP2004519447A patent/JP2006508706A/ja active Pending
- 2003-06-27 BR BR0312369-3A patent/BR0312369A/pt not_active Application Discontinuation
- 2003-06-27 PL PL03372831A patent/PL372831A1/xx not_active Application Discontinuation
- 2003-06-27 US US10/519,622 patent/US20050287192A1/en not_active Abandoned
- 2003-06-27 CA CA002488709A patent/CA2488709A1/en not_active Abandoned
- 2003-06-27 CN CNA038146207A patent/CN101389362A/zh active Pending
- 2003-06-27 EP EP03736412A patent/EP1572255A2/de not_active Withdrawn
- 2003-06-27 RU RU2005102595/15A patent/RU2005102595A/ru not_active Application Discontinuation
-
2004
- 2004-11-23 ZA ZA200409444A patent/ZA200409444B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| MXPA04011934A (es) | 2005-03-31 |
| CA2488709A1 (en) | 2004-01-15 |
| BR0312369A (pt) | 2005-04-12 |
| AU2003237753A1 (en) | 2004-01-23 |
| EP1572255A2 (de) | 2005-09-14 |
| WO2004004792A2 (en) | 2004-01-15 |
| PL372831A1 (en) | 2005-08-08 |
| ZA200409444B (en) | 2005-10-13 |
| SE0202081D0 (sv) | 2002-07-03 |
| US20050287192A1 (en) | 2005-12-29 |
| CN101389362A (zh) | 2009-03-18 |
| RU2005102595A (ru) | 2005-06-27 |
| JP2006508706A (ja) | 2006-03-16 |
| WO2004004792A3 (en) | 2007-11-01 |
| SE0202081L (sv) | 2004-01-04 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |