SE517769C2 - Kolesterol och blodfettsänkande komposition, innehållande fytosteroler, blandade med monoglycerider - Google Patents
Kolesterol och blodfettsänkande komposition, innehållande fytosteroler, blandade med monoglyceriderInfo
- Publication number
- SE517769C2 SE517769C2 SE9903915A SE9903915A SE517769C2 SE 517769 C2 SE517769 C2 SE 517769C2 SE 9903915 A SE9903915 A SE 9903915A SE 9903915 A SE9903915 A SE 9903915A SE 517769 C2 SE517769 C2 SE 517769C2
- Authority
- SE
- Sweden
- Prior art keywords
- fatty acids
- monoglycerides
- composition according
- mixed
- lowering
- Prior art date
Links
- 239000000203 mixture Substances 0.000 title claims abstract description 29
- HVYWMOMLDIMFJA-DPAQBDIFSA-N cholesterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CCCC(C)C)[C@@]1(C)CC2 HVYWMOMLDIMFJA-DPAQBDIFSA-N 0.000 title claims abstract 8
- 235000012000 cholesterol Nutrition 0.000 title claims abstract 4
- 229940068065 phytosterols Drugs 0.000 title claims abstract 4
- OGBUMNBNEWYMNJ-UHFFFAOYSA-N batilol Chemical class CCCCCCCCCCCCCCCCCCOCC(O)CO OGBUMNBNEWYMNJ-UHFFFAOYSA-N 0.000 title claims 6
- 239000008280 blood Substances 0.000 title abstract 2
- 210000004369 blood Anatomy 0.000 title abstract 2
- 235000013305 food Nutrition 0.000 claims abstract description 12
- 150000004666 short chain fatty acids Chemical class 0.000 claims abstract description 10
- 235000021391 short chain fatty acids Nutrition 0.000 claims abstract description 10
- 238000004519 manufacturing process Methods 0.000 claims abstract description 3
- 235000021122 unsaturated fatty acids Nutrition 0.000 claims abstract description 3
- 150000004670 unsaturated fatty acids Chemical class 0.000 claims abstract description 3
- GUBGYTABKSRVRQ-ASMJPISFSA-N alpha-maltose Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@@H]1O[C@@H]1[C@@H](CO)O[C@H](O)[C@H](O)[C@H]1O GUBGYTABKSRVRQ-ASMJPISFSA-N 0.000 claims abstract 3
- 229920001503 Glucan Polymers 0.000 claims abstract 2
- 150000002632 lipids Chemical class 0.000 claims abstract 2
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 claims description 21
- 235000014113 dietary fatty acids Nutrition 0.000 claims description 3
- 229930195729 fatty acid Natural products 0.000 claims description 3
- 239000000194 fatty acid Substances 0.000 claims description 3
- 150000004665 fatty acids Chemical class 0.000 claims description 3
- 235000020777 polyunsaturated fatty acids Nutrition 0.000 claims description 3
- 230000000694 effects Effects 0.000 claims description 2
- 235000021323 fish oil Nutrition 0.000 claims description 2
- FYGDTMLNYKFZSV-URKRLVJHSA-N (2s,3r,4s,5s,6r)-2-[(2r,4r,5r,6s)-4,5-dihydroxy-2-(hydroxymethyl)-6-[(2r,4r,5r,6s)-4,5,6-trihydroxy-2-(hydroxymethyl)oxan-3-yl]oxyoxan-3-yl]oxy-6-(hydroxymethyl)oxane-3,4,5-triol Chemical compound O[C@@H]1[C@@H](O)[C@H](O)[C@@H](CO)O[C@H]1OC1[C@@H](CO)O[C@@H](OC2[C@H](O[C@H](O)[C@H](O)[C@H]2O)CO)[C@H](O)[C@H]1O FYGDTMLNYKFZSV-URKRLVJHSA-N 0.000 claims 2
- 229920002498 Beta-glucan Polymers 0.000 claims 2
- LGJMUZUPVCAVPU-UHFFFAOYSA-N beta-Sitostanol Natural products C1CC2CC(O)CCC2(C)C2C1C1CCC(C(C)CCC(CC)C(C)C)C1(C)CC2 LGJMUZUPVCAVPU-UHFFFAOYSA-N 0.000 claims 2
- 239000000835 fiber Substances 0.000 claims 2
- 241000251468 Actinopterygii Species 0.000 claims 1
- LGJMUZUPVCAVPU-JFBKYFIKSA-N Sitostanol Natural products O[C@@H]1C[C@H]2[C@@](C)([C@@H]3[C@@H]([C@H]4[C@@](C)([C@@H]([C@@H](CC[C@H](C(C)C)CC)C)CC4)CC3)CC2)CC1 LGJMUZUPVCAVPU-JFBKYFIKSA-N 0.000 claims 1
- 239000002253 acid Substances 0.000 claims 1
- 239000003529 anticholesteremic agent Substances 0.000 claims 1
- 229940127226 anticholesterol agent Drugs 0.000 claims 1
- 229940076810 beta sitosterol Drugs 0.000 claims 1
- NJKOMDUNNDKEAI-UHFFFAOYSA-N beta-sitosterol Natural products CCC(CCC(C)C1CCC2(C)C3CC=C4CC(O)CCC4C3CCC12C)C(C)C NJKOMDUNNDKEAI-UHFFFAOYSA-N 0.000 claims 1
- 239000002775 capsule Substances 0.000 claims 1
- 229950005143 sitosterol Drugs 0.000 claims 1
- KZJWDPNRJALLNS-VJSFXXLFSA-N sitosterol Chemical compound C1C=C2C[C@@H](O)CC[C@]2(C)[C@@H]2[C@@H]1[C@@H]1CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]1(C)CC2 KZJWDPNRJALLNS-VJSFXXLFSA-N 0.000 claims 1
- 230000000087 stabilizing effect Effects 0.000 claims 1
- LGJMUZUPVCAVPU-HRJGVYIJSA-N stigmastanol Chemical compound C([C@@H]1CC2)[C@@H](O)CC[C@]1(C)[C@@H]1[C@@H]2[C@@H]2CC[C@H]([C@H](C)CC[C@@H](CC)C(C)C)[C@@]2(C)CC1 LGJMUZUPVCAVPU-HRJGVYIJSA-N 0.000 claims 1
- 150000003626 triacylglycerols Chemical class 0.000 claims 1
- 235000013312 flour Nutrition 0.000 abstract description 3
- 150000002148 esters Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 1
- 229930182558 Sterol Natural products 0.000 description 9
- 150000003432 sterols Chemical class 0.000 description 9
- 235000003702 sterols Nutrition 0.000 description 9
- 239000003921 oil Substances 0.000 description 7
- 235000019198 oils Nutrition 0.000 description 7
- 241000209761 Avena Species 0.000 description 4
- 235000007319 Avena orientalis Nutrition 0.000 description 4
- 238000001816 cooling Methods 0.000 description 4
- 238000003756 stirring Methods 0.000 description 4
- LDVVTQMJQSCDMK-UHFFFAOYSA-N 1,3-dihydroxypropan-2-yl formate Chemical compound OCC(CO)OC=O LDVVTQMJQSCDMK-UHFFFAOYSA-N 0.000 description 2
- HSINOMROUCMIEA-FGVHQWLLSA-N (2s,4r)-4-[(3r,5s,6r,7r,8s,9s,10s,13r,14s,17r)-6-ethyl-3,7-dihydroxy-10,13-dimethyl-2,3,4,5,6,7,8,9,11,12,14,15,16,17-tetradecahydro-1h-cyclopenta[a]phenanthren-17-yl]-2-methylpentanoic acid Chemical compound C([C@@]12C)C[C@@H](O)C[C@H]1[C@@H](CC)[C@@H](O)[C@@H]1[C@@H]2CC[C@]2(C)[C@@H]([C@H](C)C[C@H](C)C(O)=O)CC[C@H]21 HSINOMROUCMIEA-FGVHQWLLSA-N 0.000 description 1
- QVGXLLKOCUKJST-UHFFFAOYSA-N atomic oxygen Chemical compound [O] QVGXLLKOCUKJST-UHFFFAOYSA-N 0.000 description 1
- 239000003613 bile acid Substances 0.000 description 1
- 235000015895 biscuits Nutrition 0.000 description 1
- 235000008429 bread Nutrition 0.000 description 1
- 235000013339 cereals Nutrition 0.000 description 1
- 235000005911 diet Nutrition 0.000 description 1
- 230000000378 dietary effect Effects 0.000 description 1
- 230000029142 excretion Effects 0.000 description 1
- 230000002550 fecal effect Effects 0.000 description 1
- 230000007935 neutral effect Effects 0.000 description 1
- 239000002417 nutraceutical Substances 0.000 description 1
- 235000021436 nutraceutical agent Nutrition 0.000 description 1
- 235000016709 nutrition Nutrition 0.000 description 1
- 230000035764 nutrition Effects 0.000 description 1
- 229910052760 oxygen Inorganic materials 0.000 description 1
- 239000001301 oxygen Substances 0.000 description 1
- 239000003381 stabilizer Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
- A61K31/716—Glucans
- A61K31/718—Starch or degraded starch, e.g. amylose, amylopectin
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/105—Plant extracts, their artificial duplicates or their derivatives
- A23L33/11—Plant sterols or derivatives thereof, e.g. phytosterols
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/20—Reducing nutritive value; Dietetic products with reduced nutritive value
- A23L33/21—Addition of substantially indigestible substances, e.g. dietary fibres
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
- A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2002/00—Food compositions, function of food ingredients or processes for food or foodstuffs
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Botany (AREA)
- Polymers & Plastics (AREA)
- Food Science & Technology (AREA)
- Nutrition Science (AREA)
- Molecular Biology (AREA)
- Emergency Medicine (AREA)
- Diabetes (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Obesity (AREA)
- Hematology (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Organic Chemistry (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Fats And Perfumes (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Edible Oils And Fats (AREA)
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9903915A SE517769C2 (sv) | 1999-10-29 | 1999-10-29 | Kolesterol och blodfettsänkande komposition, innehållande fytosteroler, blandade med monoglycerider |
| EP00975114A EP1227816A1 (de) | 1999-10-29 | 2000-10-27 | Cholesterol senkende und blutlipide senkende zusammensetzung |
| PCT/SE2000/002100 WO2001030359A1 (en) | 1999-10-29 | 2000-10-27 | Cholesterol lowering and blood lipids lowering composition |
| AU13211/01A AU1321101A (en) | 1999-10-29 | 2000-10-27 | Cholesterol lowering and blood lipids lowering composition |
| US10/111,614 US7785620B1 (en) | 1999-10-29 | 2000-10-27 | Cholesterol lowering and blood lipids lowering composition |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE9903915A SE517769C2 (sv) | 1999-10-29 | 1999-10-29 | Kolesterol och blodfettsänkande komposition, innehållande fytosteroler, blandade med monoglycerider |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE9903915D0 SE9903915D0 (sv) | 1999-10-29 |
| SE9903915L SE9903915L (sv) | 2001-04-30 |
| SE517769C2 true SE517769C2 (sv) | 2002-07-16 |
Family
ID=20417537
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE9903915A SE517769C2 (sv) | 1999-10-29 | 1999-10-29 | Kolesterol och blodfettsänkande komposition, innehållande fytosteroler, blandade med monoglycerider |
Country Status (5)
| Country | Link |
|---|---|
| US (1) | US7785620B1 (de) |
| EP (1) | EP1227816A1 (de) |
| AU (1) | AU1321101A (de) |
| SE (1) | SE517769C2 (de) |
| WO (1) | WO2001030359A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU2002233639B2 (en) * | 2001-02-15 | 2007-03-01 | Adeka Corporation | Products containing $G(b)-glucan |
| FI20010780A0 (fi) | 2001-04-12 | 2001-04-12 | Raisio Benecol Oy | Parannetut koostumukset |
| US7732000B2 (en) | 2002-06-20 | 2010-06-08 | General Mills, Inc. | Food intermediate having sequestered phytosteryl esters in a polysaccharide matrix |
| CA2493645A1 (en) * | 2002-07-23 | 2004-01-29 | Nutrinova Nutrition Specialties & Food Ingredients Gmbh | Cholesterol-reducing agent made of dietary fibre and cholesterol-reducing substances |
| EP1600062A1 (de) * | 2004-05-25 | 2005-11-30 | Cognis IP Management GmbH | Orale und/oder topische Zusammensetzung enthaltend Prebiotiken und Sterolen |
| EP1600060A1 (de) * | 2004-05-25 | 2005-11-30 | Cognis IP Management GmbH | Orale und/oder topische Zusammensetzung enthaltend Prebiotiken und Fettsäuren |
| EP1614357A1 (de) * | 2004-07-10 | 2006-01-11 | Cognis IP Management GmbH | Nahrungsergänzung enthaltend Prebiotiken und Fettsäuren |
| WO2007090289A1 (en) * | 2006-02-09 | 2007-08-16 | National Research Council Of Canada | Combinations of botanical extracts for promoting cardiovascular health |
| IT201800002663A1 (it) * | 2018-02-13 | 2019-08-13 | Ciro Langella | Complesso multifunzionale per la produzione di nutraceutici alimentari, farmaci o cosmetici |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ZA72698B (en) | 1972-02-03 | 1973-09-26 | Liebenberg R W | Method of preparing medicinal compositions |
| US4218334A (en) | 1975-06-06 | 1980-08-19 | Henkel Corporation | Phytosterol blends |
| JPS6115647A (ja) * | 1984-06-30 | 1986-01-23 | Asahi Denka Kogyo Kk | 油脂食品 |
| US4996063A (en) * | 1989-06-30 | 1991-02-26 | The United States Of America, As Represented By The Secretary Of Agriculture | Method for making a soluble dietary fiber composition from oats |
| RU2095367C1 (ru) | 1991-05-03 | 1997-11-10 | Райсион Техтаат ой АБ | Вещество, понижающее уровень холестерина в сыворотке крови, и способ его получения |
| CA2091152C (en) | 1993-03-05 | 2005-05-03 | Kirsten Westesen | Solid lipid particles, particles of bioactive agents and methods for the manfuacture and use thereof |
| EP0756828B2 (de) * | 1995-08-04 | 2010-09-22 | N.V. Nutricia | Diätfasern enthaltende Nahrungszusammensetzung |
| US5883273A (en) * | 1996-01-26 | 1999-03-16 | Abbott Laboratories | Polyunsaturated fatty acids and fatty acid esters free of sterols and phosphorus compounds |
| US6423363B1 (en) | 1997-08-22 | 2002-07-23 | Lipton, Division Of Conopco, Inc. | Aqueous dispersion |
| ES2222553T3 (es) | 1997-08-22 | 2005-02-01 | Unilever N.V. | Producto alimenticio a base de grasa que comprende esteroles. |
| FI974648A (fi) * | 1997-09-09 | 1999-05-06 | Raisio Benecol Oy | Hydroksihappo-, maitohappo- ja hydroksialkanoaattiesterit ja niiden käyttö |
| DE19750453A1 (de) * | 1997-11-14 | 1999-05-27 | Henkel Kgaa | Verwendung von Wirkstoffmischungen zur Herstellung von hypocholesterinämischen Mitteln |
| US6149961A (en) * | 1997-11-21 | 2000-11-21 | W. K. Kellogg Institute | Fat substitute formulation and methods for utilizing same |
| CN1267030C (zh) | 1998-03-24 | 2006-08-02 | 花王株式会社 | 饮料产品 |
-
1999
- 1999-10-29 SE SE9903915A patent/SE517769C2/sv not_active IP Right Cessation
-
2000
- 2000-10-27 AU AU13211/01A patent/AU1321101A/en not_active Abandoned
- 2000-10-27 WO PCT/SE2000/002100 patent/WO2001030359A1/en not_active Application Discontinuation
- 2000-10-27 US US10/111,614 patent/US7785620B1/en not_active Expired - Fee Related
- 2000-10-27 EP EP00975114A patent/EP1227816A1/de active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| SE9903915D0 (sv) | 1999-10-29 |
| WO2001030359A1 (en) | 2001-05-03 |
| US7785620B1 (en) | 2010-08-31 |
| EP1227816A1 (de) | 2002-08-07 |
| AU1321101A (en) | 2001-05-08 |
| SE9903915L (sv) | 2001-04-30 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |