SE514342C2 - Metod, anordning och användning vid implantat för att tillförsäkra tillförsel av bioaktiv substans till implantatets omgivande ben och/eller vävnad - Google Patents

Metod, anordning och användning vid implantat för att tillförsäkra tillförsel av bioaktiv substans till implantatets omgivande ben och/eller vävnad

Info

Publication number
SE514342C2
SE514342C2 SE9901972A SE9901972A SE514342C2 SE 514342 C2 SE514342 C2 SE 514342C2 SE 9901972 A SE9901972 A SE 9901972A SE 9901972 A SE9901972 A SE 9901972A SE 514342 C2 SE514342 C2 SE 514342C2
Authority
SE
Sweden
Prior art keywords
implant
bioactive substance
release
bodies
space
Prior art date
Application number
SE9901972A
Other languages
English (en)
Swedish (sv)
Other versions
SE9901972L (sv
SE9901972D0 (sv
Inventor
Jan Hall
Lennart Loeoef
Original Assignee
Nobel Biocare Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nobel Biocare Ab filed Critical Nobel Biocare Ab
Priority to SE9901972A priority Critical patent/SE514342C2/sv
Publication of SE9901972D0 publication Critical patent/SE9901972D0/xx
Priority to DE60031991T priority patent/DE60031991T2/de
Priority to JP2000620892A priority patent/JP2003500161A/ja
Priority to PCT/SE2000/001029 priority patent/WO2000072778A1/en
Priority to AT00937438T priority patent/ATE345746T1/de
Priority to AU52611/00A priority patent/AU779806B2/en
Priority to EP00937438A priority patent/EP1207802B1/en
Priority to ES00937438T priority patent/ES2274791T3/es
Priority to CA2373703A priority patent/CA2373703C/en
Priority to US09/980,009 priority patent/US6918766B1/en
Publication of SE9901972L publication Critical patent/SE9901972L/xx
Publication of SE514342C2 publication Critical patent/SE514342C2/sv

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61CDENTISTRY; APPARATUS OR METHODS FOR ORAL OR DENTAL HYGIENE
    • A61C8/00Means to be fixed to the jaw-bone for consolidating natural teeth or for fixing dental prostheses thereon; Dental implants; Implanting tools
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/14Macromolecular materials
    • A61L27/22Polypeptides or derivatives thereof, e.g. degradation products
    • A61L27/24Collagen
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L27/00Materials for grafts or prostheses or for coating grafts or prostheses
    • A61L27/50Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
    • A61L27/54Biologically active materials, e.g. therapeutic substances
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2/2803Bones for mandibular reconstruction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2002/2817Bone stimulation by chemical reactions or by osteogenic or biological products for enhancing ossification, e.g. by bone morphogenetic or morphogenic proteins [BMP] or by transforming growth factors [TGF]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/28Bones
    • A61F2/2875Skull or cranium
    • A61F2002/2889Maxillary, premaxillary or molar implants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/30Joints
    • A61F2002/30001Additional features of subject-matter classified in A61F2/28, A61F2/30 and subgroups thereof
    • A61F2002/30003Material related properties of the prosthesis or of a coating on the prosthesis
    • A61F2002/3006Properties of materials and coating materials
    • A61F2002/30062(bio)absorbable, biodegradable, bioerodable, (bio)resorbable, resorptive
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2210/00Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof
    • A61F2210/0004Particular material properties of prostheses classified in groups A61F2/00 - A61F2/26 or A61F2/82 or A61F9/00 or A61F11/00 or subgroups thereof bioabsorbable
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2310/00Prostheses classified in A61F2/28 or A61F2/30 - A61F2/44 being constructed from or coated with a particular material
    • A61F2310/00005The prosthesis being constructed from a particular material
    • A61F2310/00365Proteins; Polypeptides; Degradation products thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/40Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
    • A61L2300/412Tissue-regenerating or healing or proliferative agents
    • A61L2300/414Growth factors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61LMETHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
    • A61L2300/00Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
    • A61L2300/60Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a special physical form
    • A61L2300/602Type of release, e.g. controlled, sustained, slow

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Dermatology (AREA)
  • Transplantation (AREA)
  • Biophysics (AREA)
  • Dentistry (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Prostheses (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SE9901972A 1999-05-31 1999-05-31 Metod, anordning och användning vid implantat för att tillförsäkra tillförsel av bioaktiv substans till implantatets omgivande ben och/eller vävnad SE514342C2 (sv)

Priority Applications (10)

Application Number Priority Date Filing Date Title
SE9901972A SE514342C2 (sv) 1999-05-31 1999-05-31 Metod, anordning och användning vid implantat för att tillförsäkra tillförsel av bioaktiv substans till implantatets omgivande ben och/eller vävnad
US09/980,009 US6918766B1 (en) 1999-05-31 2000-05-23 Method, arrangement and use of an implant for ensuring delivery of bioactive substance to the bone and/or tissue surrounding the implant
AT00937438T ATE345746T1 (de) 1999-05-31 2000-05-23 Implantat zur sicherstellung der verabreichung einer bioaktiven substanz im knochen und/oder im gewebe um das implantat
JP2000620892A JP2003500161A (ja) 1999-05-31 2000-05-23 インプラントの周囲の骨および/または組織への生物活性物質の送出しを確実にするためのインプラントの方法、構成、および使用
PCT/SE2000/001029 WO2000072778A1 (en) 1999-05-31 2000-05-23 Method, arrangement and use of an implant for ensuring delivery of bioactive substance to the bone and/or tissue surrounding the implant
DE60031991T DE60031991T2 (de) 1999-05-31 2000-05-23 Implantat zur sicherstellung der verabreichung einer bioaktiven substanz im knochen und/oder im gewebe um das implantat
AU52611/00A AU779806B2 (en) 1999-05-31 2000-05-23 Method, arrangement and use of an implant for ensuring delivery of bioactive substance to the bone and/or tissue surrounding the implant
EP00937438A EP1207802B1 (en) 1999-05-31 2000-05-23 Implant for ensuring delivery of bioactive substance to the bone and/or tissue surrounding the implant
ES00937438T ES2274791T3 (es) 1999-05-31 2000-05-23 Implante para asegurar la liberacion de una sustancia bioactiva al hueso y/o al tejido que rodea al implante.
CA2373703A CA2373703C (en) 1999-05-31 2000-05-23 Method, arrangement and use of an implant for ensuring delivery of bioactive substance to the bone and/or tissue surrounding the implant

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE9901972A SE514342C2 (sv) 1999-05-31 1999-05-31 Metod, anordning och användning vid implantat för att tillförsäkra tillförsel av bioaktiv substans till implantatets omgivande ben och/eller vävnad

Publications (3)

Publication Number Publication Date
SE9901972D0 SE9901972D0 (sv) 1999-05-31
SE9901972L SE9901972L (sv) 2000-12-01
SE514342C2 true SE514342C2 (sv) 2001-02-12

Family

ID=20415800

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9901972A SE514342C2 (sv) 1999-05-31 1999-05-31 Metod, anordning och användning vid implantat för att tillförsäkra tillförsel av bioaktiv substans till implantatets omgivande ben och/eller vävnad

Country Status (10)

Country Link
US (1) US6918766B1 (ar)
EP (1) EP1207802B1 (ar)
JP (1) JP2003500161A (ar)
AT (1) ATE345746T1 (ar)
AU (1) AU779806B2 (ar)
CA (1) CA2373703C (ar)
DE (1) DE60031991T2 (ar)
ES (1) ES2274791T3 (ar)
SE (1) SE514342C2 (ar)
WO (1) WO2000072778A1 (ar)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003055405A1 (en) 2001-12-21 2003-07-10 Nobel Biocare Ab (Publ) Method for producing a surface structure on an implant, and such an implant

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20060078847A1 (en) * 2000-09-29 2006-04-13 Kwan Norman H Dental implant system and additional methods of attachment
SE519564C2 (sv) * 2001-07-04 2003-03-11 Nobel Biocare Ab Implantat, t ex dentalt implantat, belagt med bentillväxtstimulerande medel
US7615070B2 (en) * 2002-10-11 2009-11-10 Spineco, Inc. Electro-stimulation and medical delivery device
SE526745C2 (sv) * 2003-04-17 2005-11-01 Nobel Biocare Ab Fixtur för förankring i käkben
US8372419B2 (en) 2004-03-10 2013-02-12 Scil Technology Gmbh Coated implants, their manufacturing and use thereof
US7510397B2 (en) * 2004-10-15 2009-03-31 Hochman Mark N Method and apparatus for performing maxillary sinus elevation
US20060093646A1 (en) * 2004-10-28 2006-05-04 Cima Michael J Orthopedic and dental implant devices providing controlled drug delivery
WO2007001624A2 (en) * 2005-06-28 2007-01-04 Microchips, Inc. Medical and dental implant devices for controlled drug delivery
WO2007047556A2 (en) * 2005-10-14 2007-04-26 Microchips, Inc. Passive wear-indicating sensor for implantable prosthetic device
US8551124B2 (en) 2007-04-20 2013-10-08 Stryker Trauma Gmbh Implantation pin, fixation device and method for implanting the implantation pin
ES2304117B1 (es) * 2008-01-25 2009-08-24 Marcela Ridao Dalmau Dispositivo para la conformacion de la cavidad sinusal maxilar.
KR100944217B1 (ko) * 2008-02-29 2010-02-24 (주)트리플씨메디칼 임플란트의 픽스츄어
US20090298015A1 (en) * 2008-05-28 2009-12-03 Global Implant Solutions, Llc Digital Abutment For Dental Implant System
US9095396B2 (en) * 2008-07-02 2015-08-04 Zimmer Dental, Inc. Porous implant with non-porous threads
EP2143451A1 (en) 2008-07-11 2010-01-13 Nobel Biocare Services AG Bone implant application
US20100015571A1 (en) * 2008-07-15 2010-01-21 Global Implant Solutions, Llc Flexible Abutment For Use With A Dental Implant
KR100931645B1 (ko) 2008-09-25 2009-12-14 주식회사 바이오머테리얼즈코리아 치열 교정용 스크류
EP2174607B1 (en) * 2008-10-10 2014-05-07 Stryker Trauma GmbH Implantation pin kit and method for implanting an implantation pin
DE102008055551B4 (de) * 2008-12-19 2018-01-11 Roman Zolow Implantat
GB2523828A (en) 2014-03-07 2015-09-09 Nobel Biocare Services Ag Dental implant
GB2523827A (en) 2014-03-07 2015-09-09 Nobel Biocare Services Ag Dental implant
WO2016172026A1 (en) 2015-04-20 2016-10-27 The Board Of Regents Of The University Of Texas System Clec11a is a bone growth agent

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4175326A (en) * 1977-10-26 1979-11-27 Forsyth Dental Infirmary For Children Hollow-fiber devices for and a method of the treament and diagnosis of oral diseases
US4685883A (en) * 1983-09-12 1987-08-11 Jernberg Gary R Local delivery of chemotherapeutic agents for the treatment of periodontal disease
US4764377A (en) * 1983-10-07 1988-08-16 The Forsyth Dental Infirmary For Children Intra-pocket drug delivery devices for treatment of periodontal diseases
DE3601787A1 (de) * 1986-01-22 1987-07-23 Cox Kirsten Verfahren zum applizieren von wirkstoffen und dafuer geeigneten applikator
US4744755A (en) * 1986-08-13 1988-05-17 Ross Systems Corporation Dental implant and method for installing same
US4994273A (en) * 1987-11-02 1991-02-19 Merck & Co., Inc. Solubility modulated drug delivery device
US5700479A (en) * 1988-12-23 1997-12-23 Guidor Ab Surgical element and method for selective tissue regeneration
US5059123A (en) * 1990-05-14 1991-10-22 Jernberg Gary R Periodontal barrier and method for aiding periodontal tissue regeneration
DE69232374T2 (de) * 1991-04-08 2002-08-29 Sumitomo Pharma Poröse feste zubereitung, die eine physiologische aktive proteinverbindung enthält
US5458884A (en) * 1992-09-10 1995-10-17 Britton; Peter Bioerodible device for administering active ingredients
US5503558A (en) * 1993-11-12 1996-04-02 Mcgill University Osseointegration promoting implant composition, implant assembly and method therefor
US5863201A (en) * 1994-11-30 1999-01-26 Implant Innovations, Inc. Infection-blocking dental implant
US5702449A (en) * 1995-06-07 1997-12-30 Danek Medical, Inc. Reinforced porous spinal implants
AU1369297A (en) * 1995-12-18 1997-07-14 Degussa A.G. Medical implant
US6530896B1 (en) * 1996-05-13 2003-03-11 James B. Elliott Apparatus and method for introducing an implant
WO1998017330A1 (en) * 1996-10-24 1998-04-30 Sdgi Holdings, Inc. Ceramic fusion implants and compositions containing osteoinductive factors
US6413089B1 (en) * 1999-02-10 2002-07-02 Arthur Ashman Immediate post-extraction implant
IT1307829B1 (it) * 1999-12-21 2001-11-19 Consiglio Nazionale Ricerche Protesi dentale con mezzi per il rilascio di farmaci o fattorispecifici atti ad impedire l'insorgenza di infezioni e/o promuovere
IL142933A0 (en) * 2001-05-03 2002-04-21 Dentis Technology Ltd Polymeric dental implant and method for use thereof
US7008226B2 (en) * 2002-08-23 2006-03-07 Woodwelding Ag Implant, in particular a dental implant

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2003055405A1 (en) 2001-12-21 2003-07-10 Nobel Biocare Ab (Publ) Method for producing a surface structure on an implant, and such an implant

Also Published As

Publication number Publication date
ATE345746T1 (de) 2006-12-15
SE9901972L (sv) 2000-12-01
DE60031991D1 (de) 2007-01-04
EP1207802B1 (en) 2006-11-22
AU5261100A (en) 2000-12-18
EP1207802A1 (en) 2002-05-29
ES2274791T3 (es) 2007-06-01
JP2003500161A (ja) 2003-01-07
CA2373703C (en) 2010-06-22
CA2373703A1 (en) 2000-12-07
WO2000072778A1 (en) 2000-12-07
SE9901972D0 (sv) 1999-05-31
DE60031991T2 (de) 2007-12-20
US6918766B1 (en) 2005-07-19
AU779806B2 (en) 2005-02-10

Similar Documents

Publication Publication Date Title
SE514342C2 (sv) Metod, anordning och användning vid implantat för att tillförsäkra tillförsel av bioaktiv substans till implantatets omgivande ben och/eller vävnad
Schliephake et al. Effect of RGD peptide coating of titanium implants on periimplant bone formation in the alveolar crest: an experimental pilot study in dogs
Bernhardt et al. Osteoconductive modifications of Ti-implants in a goat defect model: characterization of bone growth with SR μCT and histology
US4964801A (en) Endosseous implant having polycapillary structure
Lovschall et al. Pulp-capping with recombinant human insulin-like growth factor I (rhIGF-I) in rat molars
US4959054A (en) Pharmaceutically protected percutaneous devices
SE510152C2 (sv) Anordning för ventilation av mellanörat
US8771361B2 (en) Arrangement for increasing the stress resistance of implants and one such implant
JPS63158044A (ja) 骨内部成長室
Jimbo et al. The effect of different surgical drilling procedures on full laser‐etched microgrooves surface‐treated implants: an experimental study in sheep
Khandaker et al. Effect of collagen-polycaprolactone nanofibers matrix coating on the in vitro cytocompatibility and in vivo bone responses of titanium
MacDonald et al. Heat and radiofrequency plasma glow discharge pretreatment of a titanium alloy promote bone formation and osseointegration
Cha et al. Orthodontic tunnel miniscrews with and without TiO 2 nanotube arrays as a drug-delivery system: in vivo study
US20210244513A1 (en) Device and method for treatment of an artificial bone implant with blood
US10932910B2 (en) Nanofiber coating to improve biological and mechanical performance of joint prosthesis
Ivanovski et al. Impact of autologous platelet concentrates on the osseointegration of dental implants
EP0720833A1 (en) Device for studying and/or influencing the anchorage of implants in living biological tissue
JP2003180699A (ja) 関節軟骨治療用インプラント
Pi-Anfruns et al. Guided Bone Regeneration (GBR) for Implants in the Aesthetic Zone
Bryington Molecular assessment of endosseous implant adherent cellular phenotypes in man
CN117230148A (zh) 一种检测屏障膜细菌穿透性的方法及所用装置
Zohar et al. Mechanism of action of platelet rich plasma on bone healing
Schmidt et al. Drug Loaded, Biodegradable Nerve Conduits for the Simultaneous Chemical and Electrical Stimulation of Neural Cells as a Therapeutic Approach for Peripheral Nerve Regeneration
Salim et al. Osseo integration enhancement to titanium oxide surface by osteon TM (collagen type I and hydroxyapatite crystals)(Histological study on rabbits)
Yun et al. Wettability and drug delivery of functionally graded nano-micro porous titanium surface

Legal Events

Date Code Title Description
NUG Patent has lapsed