SE448190B - Sett att bestemma fc-dels-bindande bakteriella polypeptider - Google Patents
Sett att bestemma fc-dels-bindande bakteriella polypeptiderInfo
- Publication number
- SE448190B SE448190B SE8502722A SE8502722A SE448190B SE 448190 B SE448190 B SE 448190B SE 8502722 A SE8502722 A SE 8502722A SE 8502722 A SE8502722 A SE 8502722A SE 448190 B SE448190 B SE 448190B
- Authority
- SE
- Sweden
- Prior art keywords
- protein
- polypeptide
- antibody
- binding
- immunological
- Prior art date
Links
- 229920001184 polypeptide Polymers 0.000 title claims abstract description 44
- 102000004196 processed proteins & peptides Human genes 0.000 title claims abstract description 44
- 108090000765 processed proteins & peptides Proteins 0.000 title claims abstract description 44
- 230000001580 bacterial effect Effects 0.000 title claims abstract description 7
- 238000000034 method Methods 0.000 claims abstract description 42
- 108060003951 Immunoglobulin Proteins 0.000 claims abstract description 15
- 102000018358 immunoglobulin Human genes 0.000 claims abstract description 15
- 230000008105 immune reaction Effects 0.000 claims abstract description 7
- 230000000694 effects Effects 0.000 claims abstract description 6
- 102000004169 proteins and genes Human genes 0.000 claims description 54
- 108090000623 proteins and genes Proteins 0.000 claims description 54
- 230000001900 immune effect Effects 0.000 claims description 11
- 230000002860 competitive effect Effects 0.000 claims description 7
- 238000010324 immunological assay Methods 0.000 claims description 7
- 101710120037 Toxin CcdB Proteins 0.000 claims description 2
- 238000002360 preparation method Methods 0.000 abstract description 12
- VRDIULHPQTYCLN-UHFFFAOYSA-N Prothionamide Chemical compound CCCC1=CC(C(N)=S)=CC=N1 VRDIULHPQTYCLN-UHFFFAOYSA-N 0.000 abstract 1
- 238000003018 immunoassay Methods 0.000 abstract 1
- 239000000376 reactant Substances 0.000 description 15
- 230000009257 reactivity Effects 0.000 description 14
- 239000000872 buffer Substances 0.000 description 11
- 239000007790 solid phase Substances 0.000 description 11
- 238000012360 testing method Methods 0.000 description 10
- 241001465754 Metazoa Species 0.000 description 9
- 210000002966 serum Anatomy 0.000 description 9
- 241000283973 Oryctolagus cuniculus Species 0.000 description 8
- 229940072221 immunoglobulins Drugs 0.000 description 8
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 7
- 239000012634 fragment Substances 0.000 description 7
- 230000003993 interaction Effects 0.000 description 6
- 238000005119 centrifugation Methods 0.000 description 5
- 239000000203 mixture Substances 0.000 description 5
- 239000008363 phosphate buffer Substances 0.000 description 5
- 241000282472 Canis lupus familiaris Species 0.000 description 4
- 239000003463 adsorbent Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 239000008280 blood Substances 0.000 description 4
- 239000011541 reaction mixture Substances 0.000 description 4
- 241001494479 Pecora Species 0.000 description 3
- 239000008351 acetate buffer Substances 0.000 description 3
- 239000012491 analyte Substances 0.000 description 3
- 238000006243 chemical reaction Methods 0.000 description 3
- 230000028993 immune response Effects 0.000 description 3
- 239000003550 marker Substances 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 230000036963 noncompetitive effect Effects 0.000 description 3
- 239000011780 sodium chloride Substances 0.000 description 3
- 239000012086 standard solution Substances 0.000 description 3
- 229920000936 Agarose Polymers 0.000 description 2
- 241000271566 Aves Species 0.000 description 2
- 241000282465 Canis Species 0.000 description 2
- 102000004190 Enzymes Human genes 0.000 description 2
- 108090000790 Enzymes Proteins 0.000 description 2
- 206010028980 Neoplasm Diseases 0.000 description 2
- 229920005654 Sephadex Polymers 0.000 description 2
- 239000012507 Sephadex™ Substances 0.000 description 2
- PXIPVTKHYLBLMZ-UHFFFAOYSA-N Sodium azide Chemical compound [Na+].[N-]=[N+]=[N-] PXIPVTKHYLBLMZ-UHFFFAOYSA-N 0.000 description 2
- 239000007983 Tris buffer Substances 0.000 description 2
- 239000002671 adjuvant Substances 0.000 description 2
- 238000001042 affinity chromatography Methods 0.000 description 2
- 239000000427 antigen Substances 0.000 description 2
- 102000036639 antigens Human genes 0.000 description 2
- 108091007433 antigens Proteins 0.000 description 2
- 239000007853 buffer solution Substances 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 239000003795 chemical substances by application Substances 0.000 description 2
- 239000007979 citrate buffer Substances 0.000 description 2
- ATDGTVJJHBUTRL-UHFFFAOYSA-N cyanogen bromide Chemical compound BrC#N ATDGTVJJHBUTRL-UHFFFAOYSA-N 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 229940088598 enzyme Drugs 0.000 description 2
- 230000003053 immunization Effects 0.000 description 2
- 238000002649 immunization Methods 0.000 description 2
- 238000002347 injection Methods 0.000 description 2
- 239000007924 injection Substances 0.000 description 2
- 239000007791 liquid phase Substances 0.000 description 2
- 239000002245 particle Substances 0.000 description 2
- 230000010412 perfusion Effects 0.000 description 2
- 239000012071 phase Substances 0.000 description 2
- 229920000136 polysorbate Polymers 0.000 description 2
- 238000001556 precipitation Methods 0.000 description 2
- 238000000746 purification Methods 0.000 description 2
- 230000035945 sensitivity Effects 0.000 description 2
- 241000894007 species Species 0.000 description 2
- 239000000725 suspension Substances 0.000 description 2
- 238000010998 test method Methods 0.000 description 2
- LENZDBCJOHFCAS-UHFFFAOYSA-N tris Chemical compound OCC(N)(CO)CO LENZDBCJOHFCAS-UHFFFAOYSA-N 0.000 description 2
- QKNYBSVHEMOAJP-UHFFFAOYSA-N 2-amino-2-(hydroxymethyl)propane-1,3-diol;hydron;chloride Chemical compound Cl.OCC(N)(CO)CO QKNYBSVHEMOAJP-UHFFFAOYSA-N 0.000 description 1
- IVLXQGJVBGMLRR-UHFFFAOYSA-N 2-aminoacetic acid;hydron;chloride Chemical compound Cl.NCC(O)=O IVLXQGJVBGMLRR-UHFFFAOYSA-N 0.000 description 1
- PMUNIMVZCACZBB-UHFFFAOYSA-N 2-hydroxyethylazanium;chloride Chemical compound Cl.NCCO PMUNIMVZCACZBB-UHFFFAOYSA-N 0.000 description 1
- GHCZTIFQWKKGSB-UHFFFAOYSA-N 2-hydroxypropane-1,2,3-tricarboxylic acid;phosphoric acid Chemical compound OP(O)(O)=O.OC(=O)CC(O)(C(O)=O)CC(O)=O GHCZTIFQWKKGSB-UHFFFAOYSA-N 0.000 description 1
- ZCYVEMRRCGMTRW-UHFFFAOYSA-N 7553-56-2 Chemical compound [I] ZCYVEMRRCGMTRW-UHFFFAOYSA-N 0.000 description 1
- 102000004506 Blood Proteins Human genes 0.000 description 1
- 108010017384 Blood Proteins Proteins 0.000 description 1
- 241000283707 Capra Species 0.000 description 1
- KRKNYBCHXYNGOX-UHFFFAOYSA-K Citrate Chemical compound [O-]C(=O)CC(O)(CC([O-])=O)C([O-])=O KRKNYBCHXYNGOX-UHFFFAOYSA-K 0.000 description 1
- 229920002271 DEAE-Sepharose Polymers 0.000 description 1
- KCXVZYZYPLLWCC-UHFFFAOYSA-N EDTA Chemical compound OC(=O)CN(CC(O)=O)CCN(CC(O)=O)CC(O)=O KCXVZYZYPLLWCC-UHFFFAOYSA-N 0.000 description 1
- 241000283086 Equidae Species 0.000 description 1
- 241000287828 Gallus gallus Species 0.000 description 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 description 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 description 1
- 241000124008 Mammalia Species 0.000 description 1
- 102000057297 Pepsin A Human genes 0.000 description 1
- 108090000284 Pepsin A Proteins 0.000 description 1
- 239000004952 Polyamide Substances 0.000 description 1
- 239000002202 Polyethylene glycol Substances 0.000 description 1
- 229920001213 Polysorbate 20 Polymers 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 229920002684 Sepharose Polymers 0.000 description 1
- 241000251539 Vertebrata <Metazoa> Species 0.000 description 1
- 239000013543 active substance Substances 0.000 description 1
- BFNBIHQBYMNNAN-UHFFFAOYSA-N ammonium sulfate Chemical compound N.N.OS(O)(=O)=O BFNBIHQBYMNNAN-UHFFFAOYSA-N 0.000 description 1
- 229910052921 ammonium sulfate Inorganic materials 0.000 description 1
- 235000011130 ammonium sulphate Nutrition 0.000 description 1
- 238000010171 animal model Methods 0.000 description 1
- 239000007864 aqueous solution Substances 0.000 description 1
- 238000003556 assay Methods 0.000 description 1
- 239000011324 bead Substances 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 238000012512 characterization method Methods 0.000 description 1
- 239000003153 chemical reaction reagent Substances 0.000 description 1
- 235000013330 chicken meat Nutrition 0.000 description 1
- VDQQXEISLMTGAB-UHFFFAOYSA-N chloramine T Chemical compound [Na+].CC1=CC=C(S(=O)(=O)[N-]Cl)C=C1 VDQQXEISLMTGAB-UHFFFAOYSA-N 0.000 description 1
- 239000002131 composite material Substances 0.000 description 1
- 230000008878 coupling Effects 0.000 description 1
- 238000010168 coupling process Methods 0.000 description 1
- 238000005859 coupling reaction Methods 0.000 description 1
- 230000006735 deficit Effects 0.000 description 1
- 238000011033 desalting Methods 0.000 description 1
- 238000003795 desorption Methods 0.000 description 1
- 238000010586 diagram Methods 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 238000010494 dissociation reaction Methods 0.000 description 1
- 230000005593 dissociations Effects 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 229940079593 drug Drugs 0.000 description 1
- 239000003814 drug Substances 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 235000013601 eggs Nutrition 0.000 description 1
- 239000003480 eluent Substances 0.000 description 1
- 238000002474 experimental method Methods 0.000 description 1
- 238000002523 gelfiltration Methods 0.000 description 1
- 150000004676 glycans Chemical class 0.000 description 1
- 230000036039 immunity Effects 0.000 description 1
- 238000000760 immunoelectrophoresis Methods 0.000 description 1
- 230000016784 immunoglobulin production Effects 0.000 description 1
- 239000003547 immunosorbent Substances 0.000 description 1
- 230000006872 improvement Effects 0.000 description 1
- 239000012535 impurity Substances 0.000 description 1
- 238000011534 incubation Methods 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 238000010255 intramuscular injection Methods 0.000 description 1
- 239000007927 intramuscular injection Substances 0.000 description 1
- 230000026045 iodination Effects 0.000 description 1
- 238000006192 iodination reaction Methods 0.000 description 1
- 229910052740 iodine Inorganic materials 0.000 description 1
- 239000011630 iodine Substances 0.000 description 1
- 238000004255 ion exchange chromatography Methods 0.000 description 1
- 210000004698 lymphocyte Anatomy 0.000 description 1
- 239000011159 matrix material Substances 0.000 description 1
- 238000005259 measurement Methods 0.000 description 1
- 150000002734 metacrylic acid derivatives Chemical class 0.000 description 1
- MYWUZJCMWCOHBA-VIFPVBQESA-N methamphetamine Chemical compound CN[C@@H](C)CC1=CC=CC=C1 MYWUZJCMWCOHBA-VIFPVBQESA-N 0.000 description 1
- 229940043515 other immunoglobulins in atc Drugs 0.000 description 1
- 230000007918 pathogenicity Effects 0.000 description 1
- 229940111202 pepsin Drugs 0.000 description 1
- -1 poly (hydroxyalkyl acrylates Chemical class 0.000 description 1
- 229920002647 polyamide Polymers 0.000 description 1
- 229920001223 polyethylene glycol Polymers 0.000 description 1
- 235000010486 polyoxyethylene sorbitan monolaurate Nutrition 0.000 description 1
- 239000000256 polyoxyethylene sorbitan monolaurate Substances 0.000 description 1
- 229920001282 polysaccharide Polymers 0.000 description 1
- 239000005017 polysaccharide Substances 0.000 description 1
- 230000001376 precipitating effect Effects 0.000 description 1
- 238000011002 quantification Methods 0.000 description 1
- 238000003127 radioimmunoassay Methods 0.000 description 1
- 230000002829 reductive effect Effects 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000007787 solid Substances 0.000 description 1
- 238000010532 solid phase synthesis reaction Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 239000000758 substrate Substances 0.000 description 1
- 239000006228 supernatant Substances 0.000 description 1
- 229960001479 tosylchloramide sodium Drugs 0.000 description 1
- 238000012549 training Methods 0.000 description 1
- 238000000108 ultra-filtration Methods 0.000 description 1
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Chemical compound O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 1
Classifications
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
- G01N33/56911—Bacteria
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
- G01N33/563—Immunoassay; Biospecific binding assay; Materials therefor involving antibody fragments
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/68—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
- G01N33/6854—Immunoglobulins
- G01N33/6857—Antibody fragments
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/825—Pretreatment for removal of interfering factors from sample
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/826—Additives, e.g. buffers, diluents, preservatives
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S436/00—Chemistry: analytical and immunological testing
- Y10S436/828—Protein A
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Immunology (AREA)
- Engineering & Computer Science (AREA)
- Molecular Biology (AREA)
- Biomedical Technology (AREA)
- Chemical & Material Sciences (AREA)
- Hematology (AREA)
- Urology & Nephrology (AREA)
- Food Science & Technology (AREA)
- General Physics & Mathematics (AREA)
- Cell Biology (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Analytical Chemistry (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Microbiology (AREA)
- Pathology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Priority Applications (7)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8502722A SE448190B (sv) | 1985-06-03 | 1985-06-03 | Sett att bestemma fc-dels-bindande bakteriella polypeptider |
| CA000509670A CA1265999A (en) | 1985-06-03 | 1986-05-21 | Method for determining certain bacterial polypeptides and antibodies directed against them |
| US06/865,853 US4752571A (en) | 1985-06-03 | 1986-05-22 | Method for determining certain bacterial polypeptides and antibodies directed against them |
| AT86850190T ATE57016T1 (de) | 1985-06-03 | 1986-05-28 | Immunologische bestimmungsmethode zum nachweis von fc-teilbinden bakteriellen polypeptiden und/oder entsprechenden antikoerpern. |
| EP86850190A EP0213093B1 (de) | 1985-06-03 | 1986-05-28 | Immunologische Bestimmungsmethode zum Nachweis von Fc-teilbinden bakteriellen Polypeptiden und/oder entsprechenden Antikörpern |
| DE8686850190T DE3674511D1 (de) | 1985-06-03 | 1986-05-28 | Immunologische bestimmungsmethode zum nachweis von fc-teilbinden bakteriellen polypeptiden und/oder entsprechenden antikoerpern. |
| JP61127857A JPH06100603B2 (ja) | 1985-06-03 | 1986-06-02 | 特定の細菌ポリペプチド及びそれに対する抗体の定量法 |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| SE8502722A SE448190B (sv) | 1985-06-03 | 1985-06-03 | Sett att bestemma fc-dels-bindande bakteriella polypeptider |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| SE8502722D0 SE8502722D0 (sv) | 1985-06-03 |
| SE8502722L SE8502722L (sv) | 1986-12-04 |
| SE448190B true SE448190B (sv) | 1987-01-26 |
Family
ID=20360424
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE8502722A SE448190B (sv) | 1985-06-03 | 1985-06-03 | Sett att bestemma fc-dels-bindande bakteriella polypeptider |
Country Status (7)
| Country | Link |
|---|---|
| US (1) | US4752571A (de) |
| EP (1) | EP0213093B1 (de) |
| JP (1) | JPH06100603B2 (de) |
| AT (1) | ATE57016T1 (de) |
| CA (1) | CA1265999A (de) |
| DE (1) | DE3674511D1 (de) |
| SE (1) | SE448190B (de) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5985599A (en) * | 1986-05-29 | 1999-11-16 | The Austin Research Institute | FC receptor for immunoglobulin |
| WO1991010911A1 (en) * | 1990-01-19 | 1991-07-25 | Repligen Corporation | Immunoassay of protein a under acidic conditions |
| US6706486B1 (en) | 1998-06-19 | 2004-03-16 | Amersham Biosciences Ab | Method for the quantitative release of natural or recombinant proteins, polypeptides or peptides |
| EP1580557A4 (de) * | 2002-11-22 | 2006-09-06 | Daiichi Pure Chemicals Co Ltd | Verfahren zur untersuchung von staphylococcus aureus |
| WO2010030393A1 (en) * | 2008-09-15 | 2010-03-18 | Millipore Corporation | Methods for quantifying protein leakage from protein based affinity chromatography resins |
| WO2014055025A1 (en) * | 2012-10-03 | 2014-04-10 | Gyros Patent Ab | Method and kit for analyte determination at acidic conditions |
| CN120153258A (zh) * | 2022-12-30 | 2025-06-13 | 上海药明生物技术有限公司 | 用于检测蛋白a的方法及其试剂盒 |
Family Cites Families (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2322533C2 (de) * | 1972-11-06 | 1986-08-28 | Pharmacia AB, Uppsala | Verfahren zum Binden von Immunoglobulin und Hilfsmittel zur Durchführung des Verfahrens |
| US3966868A (en) * | 1974-12-09 | 1976-06-29 | Hope Henry F | Strip straightening apparatus, product and method |
| SE8003732L (sv) * | 1980-05-19 | 1981-11-20 | Pharmacia Diagnostics Ab | Sett vid bestemningsmetoder involverande biospecifika affinitetsreaktioner |
| US4409330A (en) * | 1980-11-24 | 1983-10-11 | American Hoechst Corporation | Material and method for removing immunoglobulins from whole blood |
| US4471058A (en) * | 1982-07-26 | 1984-09-11 | Board Of Trustees Operating Michigan State University | Method for the detection and/or determination of a polyvalent antigen using at least two different monoclonal antibodies |
| US4590168A (en) * | 1983-02-14 | 1986-05-20 | The Children's Medical Center Corporation | Protein immunoassaying and purification |
| US4617266A (en) * | 1983-04-28 | 1986-10-14 | Genex Corporation | Production of Protein A |
-
1985
- 1985-06-03 SE SE8502722A patent/SE448190B/sv not_active IP Right Cessation
-
1986
- 1986-05-21 CA CA000509670A patent/CA1265999A/en not_active Expired - Fee Related
- 1986-05-22 US US06/865,853 patent/US4752571A/en not_active Expired - Fee Related
- 1986-05-28 DE DE8686850190T patent/DE3674511D1/de not_active Expired - Fee Related
- 1986-05-28 AT AT86850190T patent/ATE57016T1/de not_active IP Right Cessation
- 1986-05-28 EP EP86850190A patent/EP0213093B1/de not_active Expired - Lifetime
- 1986-06-02 JP JP61127857A patent/JPH06100603B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| SE8502722L (sv) | 1986-12-04 |
| US4752571A (en) | 1988-06-21 |
| CA1265999A (en) | 1990-02-20 |
| JPS6212859A (ja) | 1987-01-21 |
| EP0213093B1 (de) | 1990-09-26 |
| DE3674511D1 (de) | 1990-10-31 |
| SE8502722D0 (sv) | 1985-06-03 |
| ATE57016T1 (de) | 1990-10-15 |
| EP0213093A1 (de) | 1987-03-04 |
| JPH06100603B2 (ja) | 1994-12-12 |
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