SE432781B - Forfarande for framstellning av ett nytt antibiotiskt glykopeptidkomplex av bleomycintyp med beteckningen bu-2231 och dess komponenter bu-2231a och bu-2231b genom odling av en stam av streptoalloteichus hindustanus - Google Patents
Forfarande for framstellning av ett nytt antibiotiskt glykopeptidkomplex av bleomycintyp med beteckningen bu-2231 och dess komponenter bu-2231a och bu-2231b genom odling av en stam av streptoalloteichus hindustanusInfo
- Publication number
- SE432781B SE432781B SE7609425A SE7609425A SE432781B SE 432781 B SE432781 B SE 432781B SE 7609425 A SE7609425 A SE 7609425A SE 7609425 A SE7609425 A SE 7609425A SE 432781 B SE432781 B SE 432781B
- Authority
- SE
- Sweden
- Prior art keywords
- streptous
- lotaneusus
- gylopoptime
- bleomycine
- treasure
- Prior art date
Links
- JBMBADLYKKSXRS-FUATYRKLSA-N [(2R,3S,4S,5R,6R)-2-[(2R,3S,4S,5S,6S)-2-[(1R,2S)-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-3-[[(2R,3S)-5-[[(2S,3R)-1-[[2-[4-[4-[3-(4-aminobutylamino)propylcarbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]-1-[(2S,3R,4R,5S,6S)-5-amino-3,4-dihydroxy-6-methyloxan-2-yl]oxy-2-hydroxyethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-5-oxopentan-2-yl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate Chemical compound C[C@@H](O)[C@H](NC(=O)C[C@H](O)[C@@H](C)NC(=O)[C@@H](NC(=O)c1nc(nc(N)c1C)[C@H](CC(N)=O)NC[C@H](N)C(N)=O)[C@@H](O[C@@H]1O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OC(N)=O)[C@@H]1O)c1cnc[nH]1)C(=O)NC(O[C@@H]1O[C@@H](C)[C@@H](N)[C@@H](O)[C@H]1O)C(O)c1nc(cs1)-c1nc(cs1)C(=O)NCCCNCCCCN JBMBADLYKKSXRS-FUATYRKLSA-N 0.000 title 1
- VUPBDWQPEOWRQP-RTUCOMKBSA-N [(2R,3S,4S,5R,6R)-2-[(2R,3S,4S,5S,6S)-2-[(1S,2S)-3-[[(2R,3S)-5-[[(2S,3R)-1-[[2-[4-[4-[[4-amino-6-[3-(4-aminobutylamino)propylamino]-6-oxohexyl]carbamoyl]-1,3-thiazol-2-yl]-1,3-thiazol-2-yl]-1-[(2S,3R,4R,5S,6S)-5-amino-3,4-dihydroxy-6-methyloxan-2-yl]oxy-2-hydroxyethyl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-3-hydroxy-5-oxopentan-2-yl]amino]-2-[[6-amino-2-[(1S)-3-amino-1-[[(2S)-2,3-diamino-3-oxopropyl]amino]-3-oxopropyl]-5-methylpyrimidine-4-carbonyl]amino]-1-(1H-imidazol-5-yl)-3-oxopropoxy]-4,5-dihydroxy-6-(hydroxymethyl)oxan-3-yl]oxy-3,5-dihydroxy-6-(hydroxymethyl)oxan-4-yl] carbamate Chemical compound C[C@@H](O)[C@H](NC(=O)C[C@H](O)[C@@H](C)NC(=O)[C@@H](NC(=O)c1nc(nc(N)c1C)[C@H](CC(N)=O)NC[C@H](N)C(N)=O)[C@H](O[C@@H]1O[C@@H](CO)[C@@H](O)[C@H](O)[C@@H]1O[C@H]1O[C@H](CO)[C@@H](O)[C@H](OC(N)=O)[C@@H]1O)c1cnc[nH]1)C(=O)NC(O[C@@H]1O[C@@H](C)[C@@H](N)[C@@H](O)[C@H]1O)C(O)c1nc(cs1)-c1nc(cs1)C(=O)NCCCC(N)CC(=O)NCCCNCCCCN VUPBDWQPEOWRQP-RTUCOMKBSA-N 0.000 title 1
- 230000003115 biocidal effect Effects 0.000 title 1
- OYVAGSVQBOHSSS-WXFSZRTFSA-O bleomycin Chemical compound N([C@H](C(=O)N[C@H](C)[C@@H](O)[C@H](C)C(=O)N[C@@H]([C@H](O)C)C(=O)NCCC=1SC=C(N=1)C=1SC=C(N=1)C(=O)NCCC[S+](C)C)[C@@H](OC1C(C(O)C(O)C(CO)O1)OC1C(C(OC(N)=O)C(O)C(CO)O1)O)C=1NC=NC=1)C(=O)C1=NC([C@H](CC(N)=O)NC[C@H](N)C(N)=O)=NC(N)=C1C OYVAGSVQBOHSSS-WXFSZRTFSA-O 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K9/00—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof
- C07K9/001—Peptides having up to 20 amino acids, containing saccharide radicals and having a fully defined sequence; Derivatives thereof the peptide sequence having less than 12 amino acids and not being part of a ring structure
- C07K9/003—Peptides being substituted by heterocyclic radicals, e.g. bleomycin, phleomycin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/803—Physical recovery methods, e.g. chromatography, grinding
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/886—Streptomyces
- Y10S435/891—Streptomyces bikiniensia
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- General Chemical & Material Sciences (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Compounds Of Unknown Constitution (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US05/608,494 US4051237A (en) | 1975-08-28 | 1975-08-28 | Glycopeptide antibiotics bu-2231 a and b and process for producing same |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7609425L SE7609425L (sv) | 1977-03-01 |
| SE432781B true SE432781B (sv) | 1984-04-16 |
Family
ID=24436734
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7609425A SE432781B (sv) | 1975-08-28 | 1976-08-25 | Forfarande for framstellning av ett nytt antibiotiskt glykopeptidkomplex av bleomycintyp med beteckningen bu-2231 och dess komponenter bu-2231a och bu-2231b genom odling av en stam av streptoalloteichus hindustanus |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US4051237A (xx) |
| JP (1) | JPS5231001A (xx) |
| BE (1) | BE845513A (xx) |
| CA (1) | CA1073386A (xx) |
| DE (1) | DE2638766C2 (xx) |
| DK (1) | DK141372B (xx) |
| FR (1) | FR2321897A1 (xx) |
| GB (1) | GB1539740A (xx) |
| HU (1) | HU175049B (xx) |
| IL (1) | IL50357A (xx) |
| NL (1) | NL167199C (xx) |
| SE (1) | SE432781B (xx) |
| YU (1) | YU39084B (xx) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1540466A (en) * | 1975-10-29 | 1979-02-14 | Meiji Seika Kaisha | Antibiotic polypeptides sf-1771 and sf-1881-b and production thereof |
| JPS55102596A (en) * | 1978-12-27 | 1980-08-05 | Meiji Seika Kaisha Ltd | Novel antibiotic substance, bn-183b substance, and its preparation |
| US4314028A (en) * | 1979-07-13 | 1982-02-02 | Bristol-Myers Company | Fermentation process for producing tallysomycin compounds |
| US4246400A (en) * | 1979-07-13 | 1981-01-20 | Bristol-Myers Company | Tallysomycin compounds |
| KR910002457A (ko) * | 1989-07-10 | 1991-02-25 | 원본미기재 | 항 비루스 항생제 bu-3889v |
| US5952466A (en) * | 1997-11-12 | 1999-09-14 | Eli Lilly And Company | Reductive alkylation of glycopeptide antibiotics |
| ID18900A (id) * | 1996-11-21 | 1998-05-20 | Lilly Co Eli | Alkilasi menurun dari gliko peptida anti biotik |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1038242A (en) * | 1963-03-05 | 1966-08-10 | Zaidan Hojin Biseibutsu | Bleomycin and processes for preparation thereof |
-
1975
- 1975-08-28 US US05/608,494 patent/US4051237A/en not_active Expired - Lifetime
-
1976
- 1976-08-10 CA CA258,766A patent/CA1073386A/en not_active Expired
- 1976-08-25 YU YU02078/76A patent/YU39084B/xx unknown
- 1976-08-25 DK DK384076AA patent/DK141372B/da not_active IP Right Cessation
- 1976-08-25 IL IL50357A patent/IL50357A/xx unknown
- 1976-08-25 BE BE170073A patent/BE845513A/xx not_active IP Right Cessation
- 1976-08-25 SE SE7609425A patent/SE432781B/xx not_active IP Right Cessation
- 1976-08-25 NL NL7609449.A patent/NL167199C/xx not_active IP Right Cessation
- 1976-08-27 DE DE2638766A patent/DE2638766C2/de not_active Expired
- 1976-08-27 FR FR7625923A patent/FR2321897A1/fr active Granted
- 1976-08-27 GB GB35740/76A patent/GB1539740A/en not_active Expired
- 1976-08-27 HU HU76BI549A patent/HU175049B/hu not_active IP Right Cessation
- 1976-08-27 JP JP51101723A patent/JPS5231001A/ja active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| NL7609449A (en) | 1977-03-02 |
| DK141372C (xx) | 1980-09-01 |
| GB1539740A (en) | 1979-01-31 |
| IL50357A0 (en) | 1976-10-31 |
| FR2321897A1 (fr) | 1977-03-25 |
| DE2638766A1 (de) | 1977-07-14 |
| IL50357A (en) | 1979-07-25 |
| US4051237A (en) | 1977-09-27 |
| HU175049B (hu) | 1980-05-28 |
| NL167199B (nl) | 1981-06-16 |
| FR2321897B1 (xx) | 1978-11-17 |
| YU39084B (en) | 1984-04-30 |
| DK141372B (da) | 1980-03-03 |
| DK384076A (xx) | 1977-03-01 |
| BE845513A (fr) | 1977-02-25 |
| JPS5231001A (en) | 1977-03-09 |
| CA1073386A (en) | 1980-03-11 |
| SE7609425L (sv) | 1977-03-01 |
| DE2638766C2 (de) | 1985-07-04 |
| JPS5653318B2 (xx) | 1981-12-17 |
| YU207876A (en) | 1982-06-30 |
| NL167199C (nl) | 1981-11-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| NUG | Patent has lapsed |
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