SE427840B - Analogiforfarande for framstellning av tienamycinderivat - Google Patents

Analogiforfarande for framstellning av tienamycinderivat

Info

Publication number
SE427840B
SE427840B SE7612960A SE7612960A SE427840B SE 427840 B SE427840 B SE 427840B SE 7612960 A SE7612960 A SE 7612960A SE 7612960 A SE7612960 A SE 7612960A SE 427840 B SE427840 B SE 427840B
Authority
SE
Sweden
Prior art keywords
tienamycin
derivatives
preparation
analogy procedure
analogy
Prior art date
Application number
SE7612960A
Other languages
English (en)
Swedish (sv)
Other versions
SE7612960L (sv
Inventor
L Barash
B G Christensen
W J Leanza
J Hannah
D H-M Shih
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SE7612960L publication Critical patent/SE7612960L/xx
Publication of SE427840B publication Critical patent/SE427840B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE7612960A 1975-11-21 1976-11-19 Analogiforfarande for framstellning av tienamycinderivat SE427840B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US63429175A 1975-11-21 1975-11-21

Publications (2)

Publication Number Publication Date
SE7612960L SE7612960L (sv) 1977-05-22
SE427840B true SE427840B (sv) 1983-05-09

Family

ID=24543192

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7612960A SE427840B (sv) 1975-11-21 1976-11-19 Analogiforfarande for framstellning av tienamycinderivat

Country Status (8)

Country Link
JP (1) JPS5277083A (el)
CH (1) CH632509A5 (el)
DE (1) DE2652675A1 (el)
DK (1) DK523276A (el)
FR (1) FR2332016A1 (el)
GB (1) GB1570986A (el)
NL (1) NL189298C (el)
SE (1) SE427840B (el)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0008888B1 (en) * 1978-08-23 1983-09-21 Beecham Group Plc Beta-lactam antibacterial compounds, their preparation and pharmaceutical compositions containing them
DK456580A (da) * 1979-10-29 1981-06-04 Beecham Group Ltd Fremgangsmaade til fremstilling af bicycliske beta-lactamringholdige forbindelser
EP0044142A1 (en) * 1980-07-03 1982-01-20 Beecham Group Plc Process for the preparation of beta-lactam antibiotics
US10695322B2 (en) 2016-01-29 2020-06-30 The Johns Hopkins University Inhibitors of bacterial growth

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1004670A (en) * 1963-04-23 1965-09-15 Beecham Res Lab Penicillins
GB1348984A (en) * 1970-06-16 1974-03-27 Merck & Co Inc Antibiotics and processes for their production

Also Published As

Publication number Publication date
DK523276A (da) 1977-05-22
NL7612940A (nl) 1977-05-24
JPS5277083A (en) 1977-06-29
FR2332016A1 (fr) 1977-06-17
GB1570986A (en) 1980-07-09
CH632509A5 (en) 1982-10-15
FR2332016B1 (el) 1978-11-10
DE2652675C2 (el) 1990-02-01
NL189298C (nl) 1993-03-01
NL189298B (nl) 1992-10-01
SE7612960L (sv) 1977-05-22
DE2652675A1 (de) 1977-06-02
JPS61346B2 (el) 1986-01-08

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