US4387215A
(en)
*
|
1973-03-30 |
1983-06-07 |
Bailey William J |
Polycyclic ring-opened polymers
|
US4328204A
(en)
*
|
1977-03-02 |
1982-05-04 |
Ethicon, Inc. |
Absorbable polymer-drug compounds and method for making same
|
US4211674A
(en)
*
|
1978-04-10 |
1980-07-08 |
Polak's Frutal Works B.V. |
Cyclic acetals and ketals and their use in perfume compositions
|
US4282201A
(en)
*
|
1979-02-02 |
1981-08-04 |
Alza Corporation |
Pharmaceutical comprising drug and polymer
|
DE2928636A1
(de)
*
|
1979-07-16 |
1981-02-12 |
Hoechst Ag |
Strahlungsempfindliches gemisch und verfahren zur herstellung von reliefbildern
|
US4425473A
(en)
|
1980-02-04 |
1984-01-10 |
Toagosei Chemical Industry Co., Ltd. |
Polymerizable bicyclic orthoester compounds
|
US4304767A
(en)
*
|
1980-05-15 |
1981-12-08 |
Sri International |
Polymers of di- (and higher functionality) ketene acetals and polyols
|
US4346709A
(en)
*
|
1980-11-10 |
1982-08-31 |
Alza Corporation |
Drug delivery devices comprising erodible polymer and erosion rate modifier
|
US4322323A
(en)
*
|
1980-12-01 |
1982-03-30 |
Alza Corporation |
Erodible device comprising surfactant for modifying the rate of erosion of the device
|
US4489056A
(en)
*
|
1982-06-30 |
1984-12-18 |
Merck & Co., Inc. |
Acid anhydrides as rate controlling agent for the erosion of polymers which latter polymers have beneficial substances dispersed throughout their matrix or where the polymer matrix surrounds the beneficial substance
|
US4530840A
(en)
*
|
1982-07-29 |
1985-07-23 |
The Stolle Research And Development Corporation |
Injectable, long-acting microparticle formulation for the delivery of anti-inflammatory agents
|
JPS6067531A
(ja)
*
|
1983-09-22 |
1985-04-17 |
Toshiba Corp |
樹脂組成物
|
US4841968A
(en)
*
|
1986-09-26 |
1989-06-27 |
Southern Research Institute |
Antithrombotic/thrombolytic suture and methods of making and using the same
|
US4969872A
(en)
*
|
1989-03-08 |
1990-11-13 |
Alza Corporation |
Intravenous system for delivering a beneficial agent with delivery rate control via permeable surface area variance
|
WO1991003510A1
(en)
*
|
1989-08-28 |
1991-03-21 |
Pharmaceutical Delivery Systems, Inc. |
Bioerodible polymers useful for the controlled release of therapeutic agents
|
US5030457A
(en)
*
|
1989-08-28 |
1991-07-09 |
Pharmaceutical Delivery Systems, Inc. |
Bioerodible polymers useful for the controlled release of therapeutic agents
|
US5620700A
(en)
*
|
1990-10-30 |
1997-04-15 |
Alza Corporation |
Injectable drug delivery system and method
|
US5461140A
(en)
*
|
1992-04-30 |
1995-10-24 |
Pharmaceutical Delivery Systems |
Bioerodible polymers for solid controlled release pharmaceutical compositions
|
US6440457B1
(en)
*
|
1993-05-27 |
2002-08-27 |
Alza Corporation |
Method of administering antidepressant dosage form
|
US5912268A
(en)
*
|
1995-05-22 |
1999-06-15 |
Alza Corporation |
Dosage form and method for treating incontinence
|
US6262115B1
(en)
*
|
1995-05-22 |
2001-07-17 |
Alza Coporation |
Method for the management of incontinence
|
EP0747375A1
(en)
*
|
1995-06-05 |
1996-12-11 |
General Electric Company |
Method for making orthoester monomers
|
US6919373B1
(en)
*
|
1996-11-12 |
2005-07-19 |
Alza Corporation |
Methods and devices for providing prolonged drug therapy
|
US20040062799A1
(en)
*
|
1997-09-29 |
2004-04-01 |
Ayer Atul D. |
Therapeutic composition and delivery system for administering drug
|
US6486248B2
(en)
|
2001-01-08 |
2002-11-26 |
Milliken & Company |
Liquid colorant and method
|
US7232924B2
(en)
*
|
2001-06-11 |
2007-06-19 |
Xenoport, Inc. |
Methods for synthesis of acyloxyalkyl derivatives of GABA analogs
|
EP1404324B2
(en)
*
|
2001-06-11 |
2011-04-06 |
XenoPort, Inc. |
Prodrugs of gaba analogs, compositions and uses thereof
|
US8048917B2
(en)
|
2005-04-06 |
2011-11-01 |
Xenoport, Inc. |
Prodrugs of GABA analogs, compositions and uses thereof
|
JP2005501013A
(ja)
*
|
2001-06-11 |
2005-01-13 |
ゼノポート,インコーポレイテッド |
Gaba類似体の全身濃度が持続するアミノ酸コンジュゲート
|
US20050232995A1
(en)
*
|
2002-07-29 |
2005-10-20 |
Yam Nyomi V |
Methods and dosage forms for controlled delivery of paliperidone and risperidone
|
US20050208132A1
(en)
*
|
2002-07-29 |
2005-09-22 |
Gayatri Sathyan |
Methods and dosage forms for reducing side effects of benzisozazole derivatives
|
AU2003293423A1
(en)
|
2002-12-06 |
2004-06-30 |
Xenoport, Inc. |
Carbidopa prodrugs and uses thereof
|
WO2004053192A1
(en)
*
|
2002-12-11 |
2004-06-24 |
Xenoport, Inc. |
Orally administered dosage forms of fused gaba analog prodrugs having reduced toxicity
|
EP1608357A4
(en)
*
|
2003-03-31 |
2008-03-26 |
Xenoport Inc |
TREATMENT OR PREVENTION OF HITZEWALLUNGEN USING PRODRUGS OF GABA ANALOGUE
|
PT1660440E
(pt)
*
|
2003-08-20 |
2012-05-15 |
Xenoport Inc |
Pró-fármacos de aciloxialquilcarbamato, métodos de síntese e utilização
|
EP2354120A1
(en)
|
2003-08-20 |
2011-08-10 |
XenoPort, Inc. |
Synthesis of acyloxyalkyl carbamate prodrugs and intermediates thereof
|
US7700652B2
(en)
*
|
2003-09-11 |
2010-04-20 |
Xenoport, Inc. |
Treating urinary incontinence using prodrugs of GABA analogs
|
EP1677812A4
(en)
*
|
2003-09-17 |
2010-03-24 |
Xenoport Inc |
TREATMENT OR PREVENTION OF NON-REST LEG SYNDROME USING GABA ANALOGUE-BASED PRODRUGS
|
US7329413B1
(en)
*
|
2003-11-06 |
2008-02-12 |
Advanced Cardiovascular Systems, Inc. |
Coatings for drug delivery devices having gradient of hydration and methods for fabricating thereof
|
WO2005121070A1
(en)
*
|
2004-06-04 |
2005-12-22 |
Xenoport, Inc. |
Levodopa prodrugs, and compositions and uses thereof
|
ZA200610042B
(en)
*
|
2004-06-04 |
2008-06-25 |
Xenoport Inc |
Levodopa prodrugs, and compositions and uses thereof
|
US20060128676A1
(en)
*
|
2004-07-13 |
2006-06-15 |
Pharmacofore, Inc. |
Compositions of nicotinic agonists and therapeutic agents and methods for treating or preventing diseases or pain
|
US7566738B2
(en)
*
|
2004-11-03 |
2009-07-28 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs of sulfinic acids, methods of synthesis, and use
|
US7494985B2
(en)
*
|
2004-11-03 |
2009-02-24 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs, methods of synthesis, and use
|
CN101068538A
(zh)
*
|
2004-11-04 |
2007-11-07 |
什诺波特有限公司 |
加巴喷丁前体药物持续释放口服剂型
|
WO2006091790A1
(en)
*
|
2005-02-23 |
2006-08-31 |
Xenoport, Inc. |
Platinum-containing compounds exhibiting cytostatic activity, synthesis and methods of use
|
EP2338881A1
(en)
|
2005-02-23 |
2011-06-29 |
Prexa Pharmaceuticals, Inc. |
Dopamine transporter inhibitors for use in treatment of movement disorders and other CNS indications
|
EP1919859B1
(en)
*
|
2005-06-20 |
2010-06-02 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs of tranexamic acid and use
|
US20070049626A1
(en)
*
|
2005-08-26 |
2007-03-01 |
Tran Pierre V |
Treating premature ejaculation using gabapentin and pregabalin prodrugs
|
WO2007067495A2
(en)
*
|
2005-12-05 |
2007-06-14 |
Xenoport, Inc. |
Levodopa prodrug mesylate, compositions thereof, and uses thereof
|
DK2046393T3
(da)
|
2006-05-26 |
2014-05-12 |
Signature Therapeutics Inc |
Kontrolleret frigivelse af phenol-opioider
|
EP2044142A2
(en)
*
|
2006-06-29 |
2009-04-08 |
Medtronic, Inc. |
Poly(orthoester) polymers, and methods of making and using same
|
US9744137B2
(en)
*
|
2006-08-31 |
2017-08-29 |
Supernus Pharmaceuticals, Inc. |
Topiramate compositions and methods of enhancing its bioavailability
|
WO2008033572A1
(en)
*
|
2006-09-15 |
2008-03-20 |
Xenoport, Inc. |
Acyloxyalkyl carbamate prodrugs, methods of synthesis and use
|
US7740699B2
(en)
*
|
2006-10-05 |
2010-06-22 |
E.I. Du Pont De Nemours And Company |
Orthoformate-protected polyols
|
WO2008061226A2
(en)
|
2006-11-17 |
2008-05-22 |
Supernus Pharmaceuticals Inc. |
Sustained-release formulations of topiramate
|
MX2009006080A
(es)
*
|
2006-12-08 |
2009-07-14 |
Xenoport Inc |
Uso de profarmacos de analogos de gaba para el tratamiento de enfermedades.
|
US7829592B2
(en)
*
|
2006-12-21 |
2010-11-09 |
Xenoport, Inc. |
Catechol protected levodopa diester prodrugs, compositions, and methods of use
|
WO2008076458A1
(en)
*
|
2006-12-21 |
2008-06-26 |
Xenoport, Inc. |
Levodopa dimethyl-substituted diester prodrugs, compositions, and methods of use
|
US8956642B2
(en)
*
|
2008-04-18 |
2015-02-17 |
Medtronic, Inc. |
Bupivacaine formulation in a polyorthoester carrier
|
US8475823B2
(en)
*
|
2008-04-18 |
2013-07-02 |
Medtronic, Inc. |
Baclofen formulation in a polyorthoester carrier
|
US8399513B2
(en)
*
|
2008-10-20 |
2013-03-19 |
Xenoport, Inc. |
Levodopa prodrug mesylate hydrate
|
CN102186804A
(zh)
*
|
2008-10-20 |
2011-09-14 |
克塞诺波特公司 |
合成左旋多巴酯前药的方法
|
WO2011028234A1
(en)
*
|
2009-09-04 |
2011-03-10 |
Xenoport, Inc. |
Uses of acyloxyalkyl carbamate prodrugs of tranexamic acid
|
ES2565644T3
(es)
|
2009-11-09 |
2016-04-06 |
Xenoport, Inc. |
Composiciones farmacéuticas y formas de dosificación oral de un pre medicamento de levodopa y los métodos de utilización
|
WO2011091164A1
(en)
*
|
2010-01-22 |
2011-07-28 |
Xenoport, Inc. |
Oral dosage forms having a high loading of a tranexamic acid prodrug
|
WO2012050907A2
(en)
|
2010-09-28 |
2012-04-19 |
The Regents Of The University Of California |
Gaba agonists in the treatment of disorders associated with metabolic syndrome and gaba combinations in treatment or prophylaxis of type i diabetes
|
US10335406B2
(en)
|
2015-10-01 |
2019-07-02 |
Elysium Therapeutics, Inc. |
Opioid compositions resistant to overdose and abuse
|
US9808452B2
(en)
|
2015-10-01 |
2017-11-07 |
Elysium Therapeutics, Inc. |
Polysubunit opioid prodrugs resistant to overdose and abuse
|
CA3056239C
(en)
|
2017-03-17 |
2023-09-12 |
Elysium Therapeutics, Inc. |
Polysubunit opioid prodrugs resistant to overdose and abuse
|