SE417316B - Sett att framstella piperazinyl-kinoxalin-foreningar - Google Patents

Sett att framstella piperazinyl-kinoxalin-foreningar

Info

Publication number
SE417316B
SE417316B SE7408486A SE7408486A SE417316B SE 417316 B SE417316 B SE 417316B SE 7408486 A SE7408486 A SE 7408486A SE 7408486 A SE7408486 A SE 7408486A SE 417316 B SE417316 B SE 417316B
Authority
SE
Sweden
Prior art keywords
kinoxalin
piperazinyl
compounds
make
make piperazinyl
Prior art date
Application number
SE7408486A
Other languages
English (en)
Swedish (sv)
Other versions
SE7408486L (sv
Inventor
E L Engelhardt
Jr W C Lumma
W S Saari
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SE7408486L publication Critical patent/SE7408486L/xx
Publication of SE417316B publication Critical patent/SE417316B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/50Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with hetero atoms directly attached to ring nitrogen atoms
    • C07D241/52Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/36Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems
    • C07D241/38Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings condensed with carbocyclic rings or ring systems with only hydrogen or carbon atoms directly attached to the ring nitrogen atoms
    • C07D241/40Benzopyrazines
    • C07D241/44Benzopyrazines with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE7408486A 1973-07-13 1974-06-27 Sett att framstella piperazinyl-kinoxalin-foreningar SE417316B (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37902273A 1973-07-13 1973-07-13
US46538174A 1974-04-29 1974-04-29

Publications (2)

Publication Number Publication Date
SE7408486L SE7408486L (sv) 1975-01-14
SE417316B true SE417316B (sv) 1981-03-09

Family

ID=27008442

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7408486A SE417316B (sv) 1973-07-13 1974-06-27 Sett att framstella piperazinyl-kinoxalin-foreningar

Country Status (18)

Country Link
JP (1) JPS5037791A (de)
AU (1) AU7073174A (de)
BG (1) BG21606A3 (de)
CH (1) CH605919A5 (de)
DD (1) DD112127A5 (de)
DE (1) DE2433397A1 (de)
DK (1) DK342674A (de)
ES (1) ES428107A1 (de)
FI (1) FI193974A (de)
FR (1) FR2236499B1 (de)
GB (1) GB1440722A (de)
IE (1) IE39869B1 (de)
IL (1) IL45158A0 (de)
LU (1) LU70510A1 (de)
NL (1) NL7408705A (de)
NO (1) NO742351L (de)
RO (1) RO63539A (de)
SE (1) SE417316B (de)

Families Citing this family (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4082845A (en) * 1977-04-25 1978-04-04 Merck & Co., Inc. 3-(1-Piperazinyl)-pyrido[2,3-b]pyrazines
US4091098A (en) * 1977-04-25 1978-05-23 Merck & Co., Inc. 3-(1-PIPERAZINYL)-1,2,4-BENZOTRIAZINES AND N-oxides
US4107309A (en) * 1977-05-23 1978-08-15 American Cyanamid Company Substituted imidazo[1,2-d]-as-triazines
US4091101A (en) * 1977-06-15 1978-05-23 Merck & Co., Inc. 6-(1-Piperazinyl)quinoxaline
EP0094498A3 (de) * 1982-05-06 1985-04-03 American Cyanamid Company Antiarteriosklerotische 1-Piperazin-Derivate
ES2042395B1 (es) * 1992-02-27 1994-06-16 Promotora Catalana De Inversio Procedimiento para la obtencion de derivados de 2-ciano-3-piperacinilquinoxalinas.
FR2731221B1 (fr) * 1995-03-01 1997-05-30 Pf Medicament Nouveaux derives de l'ethyl-1 dihydro-1, 2 oxo-2 methylamino-3 quinoxaline, leur utilisation a titre de medicament et les compositions pharmaceutiques les comprenant
WO1999021850A1 (en) * 1997-10-24 1999-05-06 Neurogen Corporation 1-(2-naphthyl) and 1-(2-azanaphthyl)-4-(1-phenylmethyl)piperazines being dopamine d4 receptor subtype ligands
US6040448A (en) 1997-10-24 2000-03-21 Neurogen Corporation Certain 1-(2-naphthyl) and 1-(2-azanaphthyl)-4-(1-phenylmethyl) piperazines, dopamine receptor subtype specific ligands
WO2000012500A2 (en) * 1998-09-02 2000-03-09 Neurogen Corporation 2-aryl-4-(1-[4-heteroaryl]piperazin-1-yl) methylimidazoles: dopamine d4 receptor subtype ligands
SE9901884D0 (sv) * 1999-05-21 1999-05-21 Pharmacia & Upjohn Ab Novel compounds their use and preparation
US6465467B1 (en) 1999-05-21 2002-10-15 Biovitrum Ab Certain aryl-aliphatic and heteroaryl-aliphatic piperazinyl pyrazines and their use in the treatment of serotonin-related diseases
WO2000076984A2 (en) * 1999-05-21 2000-12-21 Biovitrum Ab Novel compounds, their use and preparation
JP4707261B2 (ja) * 2001-05-15 2011-06-22 日本エンバイロケミカルズ株式会社 キノキサリン系化合物および工業用殺菌組成物
ATE454383T1 (de) 2002-06-19 2010-01-15 Biovitrum Ab Publ Neue verbindungen, deren verwendung und herstellung
WO2004009586A1 (en) * 2002-07-19 2004-01-29 Biovitrum Ab Novel piperazinyl-pyrazinone derivatives for the treatment of 5-ht2a receptor-related disorders
SE0202287D0 (sv) * 2002-07-19 2002-07-19 Biovitrum Ab New compounds
AU2004221812B2 (en) 2003-03-19 2010-02-18 Exelixis Inc. Tie-2 modulators and methods of use
MXPA06003578A (es) * 2003-09-30 2006-08-31 Johnson & Johnson Compuestos de quinoxalina.

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL260335A (de) * 1960-01-22
CH450434A (de) * 1961-12-14 1968-01-31 Ciba Geigy Verfahren zur Herstellung von Diazinen
BE788451A (fr) * 1971-09-08 1973-03-06 Bayer Ag Nouvelles 2-amino-quinoxalines, leur procede de preparation et leur application comme insecticides, acaricides et fongicides
GB1457400A (en) * 1972-11-20 1976-12-01 Pfizer Pharmaceutical compositions containing 2-substituted quinoxa lines

Also Published As

Publication number Publication date
AU7073174A (en) 1976-01-08
NL7408705A (nl) 1975-01-15
IE39869B1 (en) 1979-01-17
RO63539A (fr) 1978-07-15
ES428107A1 (es) 1976-11-16
IE39869L (en) 1975-01-13
JPS5037791A (de) 1975-04-08
DD112127A5 (de) 1975-03-20
NO742351L (de) 1975-02-10
IL45158A0 (en) 1974-11-29
GB1440722A (en) 1976-06-23
FR2236499B1 (de) 1977-04-15
CH605919A5 (de) 1978-10-13
DE2433397A1 (de) 1975-02-06
LU70510A1 (de) 1975-03-27
FI193974A (de) 1975-01-14
SE7408486L (sv) 1975-01-14
BG21606A3 (de) 1976-07-20
FR2236499A1 (de) 1975-02-07
DK342674A (de) 1975-03-03

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