SE417090B - Forfarande att framstella farmakologiskt aktiva heterocykliska prostaglandinanaloger - Google Patents
Forfarande att framstella farmakologiskt aktiva heterocykliska prostaglandinanalogerInfo
- Publication number
- SE417090B SE417090B SE7611773A SE7611773A SE417090B SE 417090 B SE417090 B SE 417090B SE 7611773 A SE7611773 A SE 7611773A SE 7611773 A SE7611773 A SE 7611773A SE 417090 B SE417090 B SE 417090B
- Authority
- SE
- Sweden
- Prior art keywords
- procedure
- pharmacologically active
- prostaglandin analogs
- active heterocyclic
- make
- Prior art date
Links
- 150000003180 prostaglandins Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
- C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/24—Oxygen or sulfur atoms
- C07D207/26—2-Pyrrolidones
- C07D207/273—2-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
- C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D207/36—Oxygen or sulfur atoms
- C07D207/38—2-Pyrrolones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Pyrrole Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB43990/75A GB1572184A (en) | 1975-10-25 | 1975-10-25 | 12-azaprostaglandins |
| GB2127876 | 1976-05-22 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| SE7611773L SE7611773L (sv) | 1977-04-26 |
| SE417090B true SE417090B (sv) | 1981-02-23 |
Family
ID=26255241
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE7611773A SE417090B (sv) | 1975-10-25 | 1976-10-22 | Forfarande att framstella farmakologiskt aktiva heterocykliska prostaglandinanaloger |
Country Status (18)
| Country | Link |
|---|---|
| US (2) | US4138407A (no) |
| JP (1) | JPS5257168A (no) |
| AT (1) | AT359658B (no) |
| AU (1) | AU506934B2 (no) |
| CA (1) | CA1085856A (no) |
| DE (1) | DE2647969A1 (no) |
| DK (1) | DK479176A (no) |
| ES (1) | ES452649A1 (no) |
| FI (1) | FI763000A (no) |
| FR (1) | FR2328464A1 (no) |
| HU (1) | HU179416B (no) |
| IE (1) | IE44180B1 (no) |
| IL (2) | IL50644A (no) |
| NL (1) | NL7611761A (no) |
| NO (2) | NO763567L (no) |
| NZ (1) | NZ182264A (no) |
| PH (2) | PH14168A (no) |
| SE (1) | SE417090B (no) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1524818A (en) * | 1974-11-29 | 1978-09-13 | Beecham Group Ltd | 12-azaprostaglandins |
| NZ182264A (en) * | 1975-10-25 | 1979-01-11 | Beecham Group Ltd | 2-carboxyalkyl-1-hydroxyalkyl-pyrrolidin-3,5-dione or-piperidin-3,6-dione derivatives prarmaceutical compostions |
| US4187312A (en) * | 1975-10-25 | 1980-02-05 | Beecham Group Limited | 3-Hydroxy-4,4-dimethyl-5-pyrrolidone derivatives |
| IL58384A0 (en) * | 1978-10-14 | 1980-01-31 | Beecham Group Ltd | 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them |
| DE3317653A1 (de) * | 1983-05-14 | 1984-11-15 | Gödecke AG, 1000 Berlin | 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitrile, verfahren zu deren herstellung sowie deren verwendung bei der prophylaxe und therapie thrombotischer zustaende |
| ZA96338B (en) * | 1995-01-25 | 1996-10-24 | Lonza Ag | Process for the preparation of (1-hydroxycyclohexane)- acetonitrile |
| US7696243B2 (en) * | 2004-12-06 | 2010-04-13 | Merck Serono, S.A. | Pyrrolidin-2-one derivatives for use as DP1 receptor agonists |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3975399A (en) * | 1974-08-06 | 1976-08-17 | E. I. Du Pont De Nemours And Company | 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones |
| US4003911A (en) * | 1975-09-26 | 1977-01-18 | E. I. Du Pont De Nemours And Company | Selected 3-pyrrolidinones and 2,4-pyrrolidindiones |
| NZ182263A (en) * | 1975-10-25 | 1979-01-11 | Beecham Group Ltd | 2-carboxyalkyl-4,4-dimethyl-1-hydroxy-alkyl-pyrrolidin-3,5-dione derivativesand pharmaceutical compositions |
| NZ182264A (en) * | 1975-10-25 | 1979-01-11 | Beecham Group Ltd | 2-carboxyalkyl-1-hydroxyalkyl-pyrrolidin-3,5-dione or-piperidin-3,6-dione derivatives prarmaceutical compostions |
| US4177283A (en) * | 1975-10-25 | 1979-12-04 | Beecham Group Limited | Aromatic prostaglandin analogues |
| US4187312A (en) * | 1975-10-25 | 1980-02-05 | Beecham Group Limited | 3-Hydroxy-4,4-dimethyl-5-pyrrolidone derivatives |
| NZ184084A (en) * | 1976-05-22 | 1979-12-11 | Beecham Group Ltd | 2-carboxyalkyl-pyrrolid-in or piperidin-one or-dione derivatives and pharmaceutical compositions |
| IL58384A0 (en) * | 1978-10-14 | 1980-01-31 | Beecham Group Ltd | 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them |
-
1976
- 1976-10-07 NZ NZ182264A patent/NZ182264A/xx unknown
- 1976-10-08 IL IL50644A patent/IL50644A/xx unknown
- 1976-10-14 AU AU18686/76A patent/AU506934B2/en not_active Ceased
- 1976-10-15 US US05/732,726 patent/US4138407A/en not_active Expired - Lifetime
- 1976-10-19 NO NO763567A patent/NO763567L/no unknown
- 1976-10-20 FI FI763000A patent/FI763000A/fi not_active Application Discontinuation
- 1976-10-20 FR FR7631527A patent/FR2328464A1/fr active Granted
- 1976-10-21 PH PH19027A patent/PH14168A/en unknown
- 1976-10-22 CA CA263,940A patent/CA1085856A/en not_active Expired
- 1976-10-22 NL NL7611761A patent/NL7611761A/xx not_active Application Discontinuation
- 1976-10-22 IE IE2330/76A patent/IE44180B1/en unknown
- 1976-10-22 AT AT788776A patent/AT359658B/de not_active IP Right Cessation
- 1976-10-22 ES ES452649A patent/ES452649A1/es not_active Expired
- 1976-10-22 SE SE7611773A patent/SE417090B/xx unknown
- 1976-10-22 HU HU76BE1277A patent/HU179416B/hu unknown
- 1976-10-22 DE DE19762647969 patent/DE2647969A1/de not_active Withdrawn
- 1976-10-22 DK DK479176A patent/DK479176A/da not_active Application Discontinuation
- 1976-10-23 JP JP51127729A patent/JPS5257168A/ja active Pending
-
1978
- 1978-11-09 NO NO783766A patent/NO783766L/no unknown
- 1978-11-20 US US05/962,057 patent/US4341789A/en not_active Expired - Lifetime
-
1980
- 1980-04-03 IL IL59758A patent/IL59758A0/xx unknown
- 1980-10-10 PH PH24708A patent/PH16143A/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| HU179416B (en) | 1982-10-28 |
| IL50644A0 (en) | 1976-12-31 |
| FI763000A (no) | 1977-04-26 |
| ATA788776A (de) | 1980-04-15 |
| FR2328464A1 (fr) | 1977-05-20 |
| IE44180B1 (en) | 1981-09-09 |
| IE44180L (en) | 1977-04-25 |
| US4341789A (en) | 1982-07-27 |
| NO763567L (no) | 1977-04-26 |
| FR2328464B1 (no) | 1978-12-22 |
| SE7611773L (sv) | 1977-04-26 |
| ES452649A1 (es) | 1978-03-16 |
| IL50644A (en) | 1981-06-29 |
| US4138407A (en) | 1979-02-06 |
| DK479176A (da) | 1977-04-26 |
| PH14168A (en) | 1981-03-19 |
| CA1085856A (en) | 1980-09-16 |
| NO783766L (no) | 1977-04-26 |
| AU506934B2 (en) | 1980-01-31 |
| NZ182264A (en) | 1979-01-11 |
| NL7611761A (nl) | 1977-04-27 |
| DE2647969A1 (de) | 1977-05-05 |
| JPS5257168A (en) | 1977-05-11 |
| IL59758A0 (en) | 1980-06-30 |
| PH16143A (en) | 1983-07-12 |
| AU1868676A (en) | 1978-04-20 |
| AT359658B (de) | 1980-11-25 |
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