HU179416B - Process for preparing compounds with a nitrogen containing heterocycle - Google Patents

Process for preparing compounds with a nitrogen containing heterocycle

Info

Publication number
HU179416B
HU179416B HU76BE1277A HUBE001277A HU179416B HU 179416 B HU179416 B HU 179416B HU 76BE1277 A HU76BE1277 A HU 76BE1277A HU BE001277 A HUBE001277 A HU BE001277A HU 179416 B HU179416 B HU 179416B
Authority
HU
Hungary
Prior art keywords
nitrogen containing
preparing compounds
containing heterocycle
heterocycle
preparing
Prior art date
Application number
HU76BE1277A
Other languages
English (en)
Inventor
Frederick Cassidy
Gordon Wootton
Original Assignee
Beecham Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB43990/75A external-priority patent/GB1572184A/en
Application filed by Beecham Group Ltd filed Critical Beecham Group Ltd
Publication of HU179416B publication Critical patent/HU179416B/hu

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/24Oxygen or sulfur atoms
    • C07D207/262-Pyrrolidones
    • C07D207/2732-Pyrrolidones with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to other ring carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D207/00Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D207/36Oxygen or sulfur atoms
    • C07D207/382-Pyrrolones

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
HU76BE1277A 1975-10-25 1976-10-22 Process for preparing compounds with a nitrogen containing heterocycle HU179416B (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB43990/75A GB1572184A (en) 1975-10-25 1975-10-25 12-azaprostaglandins
GB2127876 1976-05-22

Publications (1)

Publication Number Publication Date
HU179416B true HU179416B (en) 1982-10-28

Family

ID=26255241

Family Applications (1)

Application Number Title Priority Date Filing Date
HU76BE1277A HU179416B (en) 1975-10-25 1976-10-22 Process for preparing compounds with a nitrogen containing heterocycle

Country Status (18)

Country Link
US (2) US4138407A (hu)
JP (1) JPS5257168A (hu)
AT (1) AT359658B (hu)
AU (1) AU506934B2 (hu)
CA (1) CA1085856A (hu)
DE (1) DE2647969A1 (hu)
DK (1) DK479176A (hu)
ES (1) ES452649A1 (hu)
FI (1) FI763000A (hu)
FR (1) FR2328464A1 (hu)
HU (1) HU179416B (hu)
IE (1) IE44180B1 (hu)
IL (2) IL50644A (hu)
NL (1) NL7611761A (hu)
NO (2) NO763567L (hu)
NZ (1) NZ182264A (hu)
PH (2) PH14168A (hu)
SE (1) SE417090B (hu)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1524818A (en) * 1974-11-29 1978-09-13 Beecham Group Ltd 12-azaprostaglandins
NZ182264A (en) * 1975-10-25 1979-01-11 Beecham Group Ltd 2-carboxyalkyl-1-hydroxyalkyl-pyrrolidin-3,5-dione or-piperidin-3,6-dione derivatives prarmaceutical compostions
US4187312A (en) * 1975-10-25 1980-02-05 Beecham Group Limited 3-Hydroxy-4,4-dimethyl-5-pyrrolidone derivatives
IL58384A0 (en) * 1978-10-14 1980-01-31 Beecham Group Ltd 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them
DE3317653A1 (de) * 1983-05-14 1984-11-15 Gödecke AG, 1000 Berlin 2-alkylthio-1-aminoalkyl-2-pyrrolin-3-carbonitrile, verfahren zu deren herstellung sowie deren verwendung bei der prophylaxe und therapie thrombotischer zustaende
ZA96338B (en) * 1995-01-25 1996-10-24 Lonza Ag Process for the preparation of (1-hydroxycyclohexane)- acetonitrile
WO2006061366A1 (en) * 2004-12-06 2006-06-15 Laboratoires Serono S.A. Pyrrolidin-2-one derivatives for use as dp1 receptor agonists

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3975399A (en) * 1974-08-06 1976-08-17 E. I. Du Pont De Nemours And Company 1,5-Disubstituted-2-pyrrolidinones, -3-pyrrolin-2-ones, and -4-pyrrolin-2-ones
US4003911A (en) * 1975-09-26 1977-01-18 E. I. Du Pont De Nemours And Company Selected 3-pyrrolidinones and 2,4-pyrrolidindiones
NZ182264A (en) * 1975-10-25 1979-01-11 Beecham Group Ltd 2-carboxyalkyl-1-hydroxyalkyl-pyrrolidin-3,5-dione or-piperidin-3,6-dione derivatives prarmaceutical compostions
US4177283A (en) * 1975-10-25 1979-12-04 Beecham Group Limited Aromatic prostaglandin analogues
US4187312A (en) * 1975-10-25 1980-02-05 Beecham Group Limited 3-Hydroxy-4,4-dimethyl-5-pyrrolidone derivatives
NZ182263A (en) * 1975-10-25 1979-01-11 Beecham Group Ltd 2-carboxyalkyl-4,4-dimethyl-1-hydroxy-alkyl-pyrrolidin-3,5-dione derivativesand pharmaceutical compositions
NZ184084A (en) * 1976-05-22 1979-12-11 Beecham Group Ltd 2-carboxyalkyl-pyrrolid-in or piperidin-one or-dione derivatives and pharmaceutical compositions
IL58384A0 (en) * 1978-10-14 1980-01-31 Beecham Group Ltd 12-aza analogues of prostcyclin their preparation and pharmaceutical composition containing them

Also Published As

Publication number Publication date
IE44180L (en) 1977-04-25
AU506934B2 (en) 1980-01-31
US4341789A (en) 1982-07-27
NO783766L (no) 1977-04-26
IL50644A (en) 1981-06-29
PH16143A (en) 1983-07-12
AT359658B (de) 1980-11-25
IL50644A0 (en) 1976-12-31
FR2328464B1 (hu) 1978-12-22
IL59758A0 (en) 1980-06-30
NO763567L (hu) 1977-04-26
PH14168A (en) 1981-03-19
FR2328464A1 (fr) 1977-05-20
SE7611773L (sv) 1977-04-26
DE2647969A1 (de) 1977-05-05
CA1085856A (en) 1980-09-16
JPS5257168A (en) 1977-05-11
FI763000A (hu) 1977-04-26
ATA788776A (de) 1980-04-15
DK479176A (da) 1977-04-26
ES452649A1 (es) 1978-03-16
SE417090B (sv) 1981-02-23
AU1868676A (en) 1978-04-20
NL7611761A (nl) 1977-04-27
US4138407A (en) 1979-02-06
NZ182264A (en) 1979-01-11
IE44180B1 (en) 1981-09-09

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