SE415020B - Forfarande for framstellning av vattenlosligt syraadditionssalt av en ester av polyenmakrolidantibiotika - Google Patents

Forfarande for framstellning av vattenlosligt syraadditionssalt av en ester av polyenmakrolidantibiotika

Info

Publication number
SE415020B
SE415020B SE7207419A SE741972A SE415020B SE 415020 B SE415020 B SE 415020B SE 7207419 A SE7207419 A SE 7207419A SE 741972 A SE741972 A SE 741972A SE 415020 B SE415020 B SE 415020B
Authority
SE
Sweden
Prior art keywords
macrolidantibiotics
polyene
ester
procedure
preparation
Prior art date
Application number
SE7207419A
Other languages
English (en)
Swedish (sv)
Inventor
C P Schaffner
W S Mechlinski
Original Assignee
Rutgers Res & Education Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rutgers Res & Education Found filed Critical Rutgers Res & Education Found
Publication of SE415020B publication Critical patent/SE415020B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00—Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/04—Heterocyclic radicals containing only oxygen as ring hetero atoms
    • C07H17/08—Hetero rings containing eight or more ring members, e.g. erythromycins
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C245/00—Compounds containing chains of at least two nitrogen atoms with at least one nitrogen-to-nitrogen multiple bond
    • C07C245/12—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom
    • C07C245/14—Diazo compounds, i.e. compounds having the free valencies of >N2 groups attached to the same carbon atom having diazo groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C245/16—Diazomethane

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Saccharide Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicinal Preparation (AREA)
SE7207419A 1971-06-07 1972-06-06 Forfarande for framstellning av vattenlosligt syraadditionssalt av en ester av polyenmakrolidantibiotika SE415020B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US05/152,460 US3945993A (en) 1971-06-07 1971-06-07 Derivatives of polyene macrolide antibiotics

Publications (1)

Publication Number Publication Date
SE415020B true SE415020B (sv) 1980-09-01

Family

ID=22543022

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7207419A SE415020B (sv) 1971-06-07 1972-06-06 Forfarande for framstellning av vattenlosligt syraadditionssalt av en ester av polyenmakrolidantibiotika

Country Status (13)

Country Link
US (1) US3945993A (en:Method)
JP (1) JPS5627519B1 (en:Method)
AR (1) AR193264A1 (en:Method)
BE (1) BE784207A (en:Method)
CA (1) CA978519A (en:Method)
CH (1) CH580642A5 (en:Method)
DE (1) DE2226338A1 (en:Method)
FR (1) FR2140407B1 (en:Method)
GB (1) GB1386325A (en:Method)
IE (1) IE36381B1 (en:Method)
NL (1) NL7207700A (en:Method)
NO (1) NO139174C (en:Method)
SE (1) SE415020B (en:Method)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1399139A (en) * 1972-07-24 1975-06-25 Prodotti Antibiotici Spa Alkyl esters of polyene antibiotics
DE2417993C2 (de) * 1974-04-11 1982-07-01 Leningradskij naučno-issledovatel'skij institut antibiotikov, Leningrad Polyenmacrolidantibiotica-Komplexe, Verfahren zu deren Herstellung und diese Verbindungen enthaltende Arzneimittel
DE2609611A1 (de) * 1975-03-13 1976-09-23 Ciba Geigy Ag Verfahren zur herstellung eines neuen antibiotikums
US4035567A (en) * 1975-10-21 1977-07-12 E. R. Squibb & Sons, Inc. Process for producing the methyl ester of amphotericin B
US4041232A (en) * 1976-02-23 1977-08-09 E. R. Squibb & Sons, Inc. Amphotericin B methyl ester salts
DE2706156C3 (de) * 1977-02-14 1981-08-20 Vsesojuznyj naučno-issledovatel'skij technologičeskij institut antibiotikov i fermentov medicinskogo naznačenija, Leningrad N,N,N-Trimethylderivate amphoterer, antimykotischer Polyenantibiotika und Verfahren zu deren Herstellung
GB1566330A (en) * 1977-02-16 1980-04-30 Farmaceutici Italia Anthracycline glycosides
US4144328A (en) * 1977-02-28 1979-03-13 Vainshtein Viktor A N,N,N-Trimethyl derivatives of polyene amphoteric antibiotics, process of producing same and pharmaceutical composition
ZA807892B (en) * 1979-12-24 1981-12-30 Dumex Ltd As Water soluble guanidine derivatives of polyene marcrolides and the esters thereof
US4308375A (en) * 1980-10-06 1981-12-29 E. R. Squibb & Sons, Inc. Method for purifying water-insoluble polyene antibiotics
US4536494A (en) * 1983-11-17 1985-08-20 Carter A Franklin Animal feed method employing natamycin
US4600706A (en) * 1983-11-17 1986-07-15 Carter A F Anti-fungal feed compositions containing natamycin
EP0350164A3 (en) * 1988-06-13 1991-07-24 Beecham Group Plc Amphotericin derivatives
EP0431874A1 (en) * 1989-12-08 1991-06-12 Beecham Group p.l.c. Novel compounds
CN101081860B (zh) * 2006-06-01 2010-04-14 上海医药工业研究院 多烯类抗生素双酯化合物
GB0712881D0 (en) * 2007-07-03 2007-08-15 Biosergen As Compounds
CN110669087B (zh) * 2018-07-02 2023-03-31 上海医药工业研究院 两性霉素b肽衍生物及其制备方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2908612A (en) * 1957-03-25 1959-10-13 Olin Mathieson Amphotericin a and its salts
US3244590A (en) * 1960-12-23 1966-04-05 Rutgers Res And Educational Fo Polyenic compounds and procedures related thereto
US3777018A (en) * 1967-03-31 1973-12-04 Schmid Inc Julius Compositions containing polyenic macro-lide and aryl derivative of aliphatic acid and method for treating hyper-lipidaemia

Also Published As

Publication number Publication date
IE36381L (en) 1972-12-07
FR2140407A1 (en:Method) 1973-01-19
DE2226338A1 (de) 1973-01-04
IE36381B1 (en) 1976-10-27
GB1386325A (en) 1975-03-05
NL7207700A (en:Method) 1972-12-11
FR2140407B1 (en:Method) 1975-08-08
BE784207A (fr) 1972-11-30
JPS5627519B1 (en:Method) 1981-06-25
CH580642A5 (en:Method) 1976-10-15
NO139174B (no) 1978-10-09
NO139174C (no) 1979-01-17
AR193264A1 (es) 1973-04-11
CA978519A (en) 1975-11-25
US3945993A (en) 1976-03-23

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