SE408412B - Forfarande for framstellning av l-3-(3,4-dihydroxi-fenyl)-2-metyl-alanin-peptider med blodtryckssenkande egenskaper - Google Patents

Forfarande for framstellning av l-3-(3,4-dihydroxi-fenyl)-2-metyl-alanin-peptider med blodtryckssenkande egenskaper

Info

Publication number
SE408412B
SE408412B SE7602135A SE7602135A SE408412B SE 408412 B SE408412 B SE 408412B SE 7602135 A SE7602135 A SE 7602135A SE 7602135 A SE7602135 A SE 7602135A SE 408412 B SE408412 B SE 408412B
Authority
SE
Sweden
Prior art keywords
dihydroxy
phenyl
methyl
preparing
procedure
Prior art date
Application number
SE7602135A
Other languages
English (en)
Other versions
SE7602135L (sv
Inventor
F Braun
K Stach
M Thiel
G Sponer
K Dietmann
Original Assignee
Boehringer Mannheim Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim Gmbh filed Critical Boehringer Mannheim Gmbh
Publication of SE7602135L publication Critical patent/SE7602135L/sv
Publication of SE408412B publication Critical patent/SE408412B/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/08Tripeptides
    • C07K5/0802Tripeptides with the first amino acid being neutral
    • C07K5/0804Tripeptides with the first amino acid being neutral and aliphatic
    • C07K5/0806Tripeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06026Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 0 or 1 carbon atom, i.e. Gly or Ala
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06078Dipeptides with the first amino acid being neutral and aromatic or cycloaliphatic
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80Antihypertensive peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
SE7602135A 1975-03-12 1976-02-23 Forfarande for framstellning av l-3-(3,4-dihydroxi-fenyl)-2-metyl-alanin-peptider med blodtryckssenkande egenskaper SE408412B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19752510634 DE2510634A1 (de) 1975-03-12 1975-03-12 L-3-(3,4-dihydroxy-phenyl)-2- methyl-alanin-peptide und verfahren zu deren herstellung

Publications (2)

Publication Number Publication Date
SE7602135L SE7602135L (sv) 1976-09-13
SE408412B true SE408412B (sv) 1979-06-11

Family

ID=5941062

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7602135A SE408412B (sv) 1975-03-12 1976-02-23 Forfarande for framstellning av l-3-(3,4-dihydroxi-fenyl)-2-metyl-alanin-peptider med blodtryckssenkande egenskaper

Country Status (23)

Country Link
US (1) US4087520A (sv)
JP (1) JPS51118739A (sv)
AR (1) AR207182A1 (sv)
AT (1) AT349662B (sv)
BE (1) BE839362A (sv)
CA (1) CA1051874A (sv)
CH (1) CH618961A5 (sv)
CS (1) CS193537B2 (sv)
DD (1) DD125548A5 (sv)
DE (1) DE2510634A1 (sv)
DK (1) DK144033C (sv)
ES (1) ES445927A1 (sv)
FR (1) FR2303535A1 (sv)
GB (1) GB1491413A (sv)
HU (1) HU171083B (sv)
IE (1) IE42785B1 (sv)
IT (1) IT1056948B (sv)
LU (1) LU74520A1 (sv)
NL (1) NL7602391A (sv)
PL (1) PL101292B1 (sv)
SE (1) SE408412B (sv)
SU (1) SU656505A3 (sv)
ZA (1) ZA761462B (sv)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PH14064A (en) * 1977-05-06 1981-01-26 Pfizer Phenylgycine derivatives,pharmaceutical compositions and method of use
JPS6026099B2 (ja) * 1977-09-21 1985-06-21 財団法人微生物化学研究会 ペプチド、その酸附加塩およびその製造法
PH14681A (en) * 1977-11-30 1981-11-10 Pfizer Phenylglycinamides useful in the treatment of ischaemic heart disease
US4743590A (en) * 1978-07-31 1988-05-10 Debarbieri Augusto In vitro and in vivo treatment of cancer cells and treatment of viruses with a tripeptide compound
US4540683A (en) * 1978-07-31 1985-09-10 Proter S.P.A. In vitro and in vivo treatment of cancer cells and treatment of viruses with a tripeptide compound
IT1134503B (it) 1980-11-28 1986-08-13 Proter Spa Composti della diclorodietilaminofenilalanina ad azione antitumorale
US4740501A (en) * 1978-07-31 1988-04-26 Debarbieri Augusto Interference of b-type retrovirus replication with a tripeptide compound
JPS5767516A (en) * 1980-09-24 1982-04-24 Microbial Chem Res Found Novel analgesic agent
US4666887A (en) * 1980-11-28 1987-05-19 Proter S.P.A. Intravenous or intraperitoneal administration of a tripeptide compound for treating cancer
US4454065A (en) * 1982-05-18 1984-06-12 Smithkline Beckman Corporation Oligopeptide prodrugs

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3803120A (en) * 1971-09-28 1974-04-09 Hoffmann La Roche Di-and tripeptides of 3-(3,4-dihydroxyphenyl)-alanine
US3891696A (en) * 1973-11-02 1975-06-24 Interx Research Corp Novel, transient pro-drug forms of l-dopa

Also Published As

Publication number Publication date
AU1189676A (en) 1977-09-15
FR2303535A1 (fr) 1976-10-08
GB1491413A (en) 1977-11-09
BE839362A (fr) 1976-09-09
PL101292B1 (pl) 1978-12-30
AT349662B (de) 1979-04-25
HU171083B (hu) 1977-11-28
IT1056948B (it) 1982-02-20
LU74520A1 (sv) 1976-09-01
NL7602391A (nl) 1976-09-14
DK103876A (da) 1976-09-13
DD125548A5 (sv) 1977-05-04
CH618961A5 (sv) 1980-08-29
DE2510634A1 (de) 1976-09-23
ATA180676A (de) 1978-09-15
DK144033C (da) 1982-04-26
SU656505A3 (ru) 1979-04-05
CA1051874A (en) 1979-04-03
US4087520A (en) 1978-05-02
IE42785L (en) 1976-09-12
FR2303535B1 (sv) 1978-11-17
JPS51118739A (en) 1976-10-18
AR207182A1 (es) 1976-09-15
ES445927A1 (es) 1977-05-01
IE42785B1 (en) 1980-10-22
CS193537B2 (en) 1979-10-31
SE7602135L (sv) 1976-09-13
DK144033B (da) 1981-11-23
ZA761462B (en) 1977-04-27

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