SE405731B - Analogiforfaranden for framstellning av nya imidazolderivat med antiinflammatorisk och analgetisk verkan - Google Patents

Analogiforfaranden for framstellning av nya imidazolderivat med antiinflammatorisk och analgetisk verkan

Info

Publication number
SE405731B
SE405731B SE7205565A SE556572A SE405731B SE 405731 B SE405731 B SE 405731B SE 7205565 A SE7205565 A SE 7205565A SE 556572 A SE556572 A SE 556572A SE 405731 B SE405731 B SE 405731B
Authority
SE
Sweden
Prior art keywords
analogical
inflammatory
procedures
preparation
analgetic effect
Prior art date
Application number
SE7205565A
Other languages
English (en)
Swedish (sv)
Inventor
K Fitzi
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH687571A external-priority patent/CH554415A/xx
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of SE405731B publication Critical patent/SE405731B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D241/00Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings
    • C07D241/02Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings
    • C07D241/10Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D241/12Heterocyclic compounds containing 1,4-diazine or hydrogenated 1,4-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7205565A 1971-05-10 1972-04-27 Analogiforfaranden for framstellning av nya imidazolderivat med antiinflammatorisk och analgetisk verkan SE405731B (sv)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
CH687571A CH554415A (de) 1970-06-01 1971-05-10 Verfahren zur herstellung von zitronensaeure durch submerse gaerung.
CH696771A CH561202A5 (ja) 1971-05-10 1971-05-11
CH697571 1971-05-12
CH425072A CH579072A5 (ja) 1971-05-10 1972-03-22

Publications (1)

Publication Number Publication Date
SE405731B true SE405731B (sv) 1978-12-27

Family

ID=27428754

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7205565A SE405731B (sv) 1971-05-10 1972-04-27 Analogiforfaranden for framstellning av nya imidazolderivat med antiinflammatorisk och analgetisk verkan

Country Status (10)

Country Link
AT (4) AT316544B (ja)
AU (1) AU472065B2 (ja)
BE (1) BE783244A (ja)
CA (1) CA1012148A (ja)
CH (5) CH561716A5 (ja)
DE (1) DE2221546A1 (ja)
FR (1) FR2137740B1 (ja)
GB (1) GB1381031A (ja)
NL (1) NL7206346A (ja)
SE (1) SE405731B (ja)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK513580A (da) * 1980-01-07 1981-07-08 Du Pont Fremgangsmaade til fremstilling af 4,5-diaryl-alfa (polyhalogenalkyl)-1h-imidazol-2-methanoler
DD201677A5 (de) * 1980-07-25 1983-08-03 Ciba Geigy Verfahren zur herstellung von trisubstituierten imidazolderivaten
US4372964A (en) * 1980-10-30 1983-02-08 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-1H-imidazole-2-methanols
GB2123831B (en) * 1981-07-20 1986-01-15 Ciba Geigy Ag Trisubstituted oxazo compounds
AU554104B2 (en) * 1981-09-01 1986-08-07 F. Hoffmann-La Roche Ag Heterocyclic compounds and fungicides containing same
EP0084756A1 (de) * 1982-01-22 1983-08-03 Ciba-Geigy Ag Trisubstituierte Oxazaverbindungen
EP0084757A1 (de) * 1982-01-25 1983-08-03 Ciba-Geigy Ag Trisubstituierte Diaza-Derivate
IL83467A0 (en) * 1986-08-15 1988-01-31 Fujisawa Pharmaceutical Co Imidazole derivatives,processes for their preparation and pharmaceutical compositions containing the same
ES2053401B1 (es) * 1992-01-13 1995-03-01 Smithkline Beecham Corp Compuestos de imidazol y procedimientos para su prepacion.
US5656644A (en) * 1994-07-20 1997-08-12 Smithkline Beecham Corporation Pyridyl imidazoles
US5916891A (en) 1992-01-13 1999-06-29 Smithkline Beecham Corporation Pyrimidinyl imidazoles
IL104369A0 (en) * 1992-01-13 1993-05-13 Smithkline Beecham Corp Novel compounds and compositions
EP0727998B1 (en) * 1993-11-08 2004-01-21 Smithkline Beecham Corporation Oxazoles for treating cytokine mediated diseases
US5620999A (en) * 1994-07-28 1997-04-15 Weier; Richard M. Benzenesulfonamide subtituted imidazolyl compounds for the treatment of inflammation
US6426360B1 (en) * 1994-07-28 2002-07-30 G D Searle & Co. 4,5-substituted imidazolyl compounds for the treatment of inflammation
CN1145623C (zh) * 1994-12-13 2004-04-14 霍夫曼-拉罗奇有限公司 咪唑衍生物
US6127545A (en) * 1997-04-18 2000-10-03 Merck & Co., Inc. Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
US6130334A (en) * 1998-04-15 2000-10-10 Merck & Co., Inc. Process for making 2-aryl-3-aryl-5-halo pyridines useful as COX-2 inhibitors
TW492959B (en) * 1997-04-18 2002-07-01 Merck & Co Inc Process for making 2-aryl-3-aryl-5-halo pyridines useful as cox-2 inhibitors
WO2000061576A1 (en) * 1999-04-09 2000-10-19 Smithkline Beecham Corporation Triarylimidazoles
CO5271680A1 (es) * 2000-02-21 2003-04-30 Smithkline Beecham Corp Compuestos
GB0007405D0 (en) * 2000-03-27 2000-05-17 Smithkline Beecham Corp Compounds

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3192211A (en) * 1962-05-03 1965-06-29 Nl Combinatie Chem Ind 5-phenyl-5-(2-pyrazyl)-hydantoin
US3538104A (en) * 1969-02-28 1970-11-03 Geigy Chem Corp Pyridyl-2-imidazolones

Also Published As

Publication number Publication date
AT319941B (de) 1975-01-10
DE2221546A1 (de) 1972-11-16
FR2137740B1 (ja) 1975-08-01
CH561717A5 (ja) 1975-05-15
NL7206346A (ja) 1972-11-14
CH579072A5 (ja) 1976-08-31
BE783244A (fr) 1972-11-10
AU4205572A (en) 1973-11-15
FR2137740A1 (ja) 1972-12-29
AT319940B (de) 1975-01-10
AT319939B (de) 1975-01-10
CH561716A5 (ja) 1975-05-15
CA1012148A (en) 1977-06-14
GB1381031A (en) 1975-01-22
CH561202A5 (ja) 1975-04-30
CH561718A5 (ja) 1975-05-15
AT316544B (de) 1974-07-10
AU472065B2 (en) 1976-05-13

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