SE402283B - Karbazoler med antiinflammatorisk, analgetisk och antireumatisk verkan - Google Patents

Karbazoler med antiinflammatorisk, analgetisk och antireumatisk verkan

Info

Publication number
SE402283B
SE402283B SE7310244A SE7310244A SE402283B SE 402283 B SE402283 B SE 402283B SE 7310244 A SE7310244 A SE 7310244A SE 7310244 A SE7310244 A SE 7310244A SE 402283 B SE402283 B SE 402283B
Authority
SE
Sweden
Prior art keywords
antireumatic
analgetic
carbazoles
inflammatory
effect
Prior art date
Application number
SE7310244A
Other languages
English (en)
Swedish (sv)
Inventor
L Berger
A J Corraz
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE402283B publication Critical patent/SE402283B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/88Carbazoles; Hydrogenated carbazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the ring system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56Ring systems containing three or more rings
    • C07D209/80[b, c]- or [b, d]-condensed
    • C07D209/82Carbazoles; Hydrogenated carbazoles
    • C07D209/86Carbazoles; Hydrogenated carbazoles with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Biomedical Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE7310244A 1972-07-24 1973-07-23 Karbazoler med antiinflammatorisk, analgetisk och antireumatisk verkan SE402283B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27414272A 1972-07-24 1972-07-24

Publications (1)

Publication Number Publication Date
SE402283B true SE402283B (sv) 1978-06-26

Family

ID=23046965

Family Applications (2)

Application Number Title Priority Date Filing Date
SE7310244A SE402283B (sv) 1972-07-24 1973-07-23 Karbazoler med antiinflammatorisk, analgetisk och antireumatisk verkan
SE7605813A SE7605813L (sv) 1972-07-24 1976-05-21 Karbazoler

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7605813A SE7605813L (sv) 1972-07-24 1976-05-21 Karbazoler

Country Status (26)

Country Link
JP (1) JPS5740144B2 (enrdf_load_stackoverflow)
KR (1) KR780000289B1 (enrdf_load_stackoverflow)
AR (1) AR205331A1 (enrdf_load_stackoverflow)
AT (1) AT325607B (enrdf_load_stackoverflow)
AU (1) AU475534B2 (enrdf_load_stackoverflow)
BE (1) BE802596A (enrdf_load_stackoverflow)
CA (1) CA1026348A (enrdf_load_stackoverflow)
CH (1) CH587819A5 (enrdf_load_stackoverflow)
DD (1) DD107681A5 (enrdf_load_stackoverflow)
DE (1) DE2337340C2 (enrdf_load_stackoverflow)
DK (1) DK138537B (enrdf_load_stackoverflow)
FI (1) FI59244C (enrdf_load_stackoverflow)
FR (1) FR2193611B1 (enrdf_load_stackoverflow)
GB (1) GB1385620A (enrdf_load_stackoverflow)
HK (1) HK49878A (enrdf_load_stackoverflow)
HU (1) HU167611B (enrdf_load_stackoverflow)
IE (1) IE37942B1 (enrdf_load_stackoverflow)
IL (1) IL42799A (enrdf_load_stackoverflow)
KE (1) KE2847A (enrdf_load_stackoverflow)
LU (1) LU68071A1 (enrdf_load_stackoverflow)
MY (1) MY7800315A (enrdf_load_stackoverflow)
NL (1) NL169877C (enrdf_load_stackoverflow)
NO (1) NO142865C (enrdf_load_stackoverflow)
SE (2) SE402283B (enrdf_load_stackoverflow)
SU (1) SU509220A3 (enrdf_load_stackoverflow)
ZA (1) ZA734047B (enrdf_load_stackoverflow)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4146542A (en) * 1978-06-12 1979-03-27 Hoffmann-La Roche Inc. Dihydrocarbazole acetic acid and esters thereof
US4150031A (en) * 1978-06-26 1979-04-17 Hoffmann-La Roche Inc. Hydroxy methyl carbazole acetic acid and esters
US4158007A (en) * 1978-08-21 1979-06-12 Hoffmann-La Roche Inc. Carbazole methyl malonates
US4501908A (en) * 1981-03-12 1985-02-26 Hoffmann-La Roche Inc. 2,3-Isopropylidene ribonic acid, 1,4-lactones
JPS6040256U (ja) * 1983-08-25 1985-03-20 伊東 璋 容器類洗浄機
DE3768097D1 (de) * 1986-01-23 1991-04-04 Merck Frosst Canada Inc Tetrahydrocarbazol-1-alkansaeuren.
ATE90076T1 (de) 1986-03-27 1993-06-15 Merck Frosst Canada Inc Tetrahydrocarbazole ester.
EP0307077A1 (en) * 1987-07-21 1989-03-15 Merck Frosst Canada Inc. Tetrahydrocarbazoles for the improvement of cyclosporin therapy
CA1326030C (en) * 1987-07-21 1994-01-11 John W. Gillard Cyclohept[b]indolealkanoic acids
PT95692A (pt) * 1989-10-27 1991-09-13 American Home Prod Processo para a preparacao de derivados de acidos indole-,indeno-,piranoindole- e tetra-hidrocarbazole-alcanoicos, ou quais sao uteis como inibidores de pla2 e da lipoxigenase
US6013808A (en) * 1998-06-16 2000-01-11 Pfizer Inc. Method of purifying carbazole ester precursors of 6-chloro-α-methyl-carbazole-2-acetic acid
JP2004010601A (ja) * 2002-06-11 2004-01-15 Nippon Steel Chem Co Ltd インドール誘導体の製造方法及びそのための有用な中間体
US7332516B2 (en) 2003-01-14 2008-02-19 Merck + Co., Inc. Geminally di-substituted NSAID derivatives as Aβ42 lowering agents
EP2960204B1 (en) * 2003-05-06 2018-06-13 Air Products And Chemicals, Inc. Hydrogen storage by reversible hydrogenation of pi-conjugated substrates
CA2535497A1 (en) * 2003-08-15 2005-02-24 Universite Laval Monomers, oligomers and polymers of 2-functionalized and 2,7-difunctionalized carbazoles
US7601856B2 (en) 2006-07-27 2009-10-13 Wyeth Benzofurans as potassium ion channel modulators
US7662831B2 (en) 2006-07-27 2010-02-16 Wyeth Llc Tetracyclic indoles as potassium channel modulators
DK2802320T3 (da) * 2011-11-15 2019-05-27 Yissum Res Dev Co Of Hebrew Univ Jerusalem Ltd Tricykliske forbindelser, sammensætninger omfattende disse og anvendelser deraf
JP5940036B2 (ja) * 2013-10-08 2016-06-29 テックフィールズ バイオケム カンパニー リミテッド 非常に速い皮膚透過率を有するアリール−及びヘテロアリールプロピオン酸の正荷電水溶性プロドラッグ
JP7747621B2 (ja) * 2020-03-25 2025-10-01 Jnc株式会社 化合物、液晶組成物および液晶表示素子

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD70880A (enrdf_load_stackoverflow) *
US3580926A (en) * 1969-11-10 1971-05-25 Parke Davis & Co Carbazole-4-alkanoic acids and tetrahydrocarbazole-4-alkanoic acids
ZA715217B (en) * 1970-08-20 1972-04-26 Org Nv Anti-inflammatory preparations

Also Published As

Publication number Publication date
BE802596A (fr) 1974-01-21
FI59244B (fi) 1981-03-31
CH587819A5 (enrdf_load_stackoverflow) 1977-05-13
NL169877C (nl) 1982-09-01
IL42799A (en) 1977-03-31
LU68071A1 (enrdf_load_stackoverflow) 1975-04-11
DD107681A5 (enrdf_load_stackoverflow) 1974-08-12
AU475534B2 (en) 1976-08-26
HK49878A (en) 1978-09-08
FR2193611B1 (enrdf_load_stackoverflow) 1976-05-14
NL169877B (nl) 1982-04-01
AU5839073A (en) 1975-01-23
AT325607B (de) 1975-10-27
FR2193611A1 (enrdf_load_stackoverflow) 1974-02-22
GB1385620A (en) 1975-02-26
FI59244C (fi) 1981-07-10
KR780000289B1 (en) 1978-08-10
DE2337340A1 (de) 1974-02-14
DK138537C (enrdf_load_stackoverflow) 1979-03-05
JPS4943973A (enrdf_load_stackoverflow) 1974-04-25
ATA649773A (de) 1975-01-15
IE37942L (en) 1974-01-24
NL7310275A (enrdf_load_stackoverflow) 1974-01-28
KE2847A (en) 1978-06-30
AR205331A1 (es) 1976-04-30
SE7605813L (sv) 1976-05-21
DE2337340C2 (de) 1985-05-02
NO142865C (no) 1980-11-05
NO142865B (no) 1980-07-28
JPS5740144B2 (enrdf_load_stackoverflow) 1982-08-25
IL42799A0 (en) 1973-10-25
IE37942B1 (en) 1977-11-23
MY7800315A (en) 1978-12-31
ZA734047B (en) 1974-03-27
DK138537B (da) 1978-09-25
CA1026348A (en) 1978-02-14
SU509220A3 (ru) 1976-03-30
HU167611B (enrdf_load_stackoverflow) 1975-11-28

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