SE400652B - METHOD OF MAKING CONJUGATE OF INSULIN WITH ACIDIC POLYSACCARIDES - Google Patents

METHOD OF MAKING CONJUGATE OF INSULIN WITH ACIDIC POLYSACCARIDES

Info

Publication number
SE400652B
SE400652B SE7511288A SE7511288A SE400652B SE 400652 B SE400652 B SE 400652B SE 7511288 A SE7511288 A SE 7511288A SE 7511288 A SE7511288 A SE 7511288A SE 400652 B SE400652 B SE 400652B
Authority
SE
Sweden
Prior art keywords
polysaccarides
insulin
acidic
making conjugate
conjugate
Prior art date
Application number
SE7511288A
Other languages
Swedish (sv)
Other versions
SE7511288L (en
Inventor
P J Mill
M A Cresswell
J G Feinberg
Original Assignee
Miles Lab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Miles Lab filed Critical Miles Lab
Publication of SE7511288L publication Critical patent/SE7511288L/en
Publication of SE400652B publication Critical patent/SE400652B/en

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/10—Enzymes or microbial cells immobilised on or in an organic carrier the carrier being a carbohydrate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/02—Algae
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/73—Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/75—Rutaceae (Rue family)
    • A61K36/752—Citrus, e.g. lime, orange or lemon
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/35—Allergens
    • A61K39/36—Allergens from pollen
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
    • A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
    • A61K47/56—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule
    • A61K47/61—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being an organic macromolecular compound, e.g. an oligomeric, polymeric or dendrimeric molecule the organic macromolecular compound being a polysaccharide or a derivative thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B37/00—Preparation of polysaccharides not provided for in groups C08B1/00 - C08B35/00; Derivatives thereof
    • C08B37/0006—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid
    • C08B37/0045—Homoglycans, i.e. polysaccharides having a main chain consisting of one single sugar, e.g. colominic acid alpha-D-Galacturonans, e.g. methyl ester of (alpha-1,4)-linked D-galacturonic acid units, i.e. pectin, or hydrolysis product of methyl ester of alpha-1,4-linked D-galacturonic acid units, i.e. pectinic acid; Derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N11/00—Carrier-bound or immobilised enzymes; Carrier-bound or immobilised microbial cells; Preparation thereof
    • C12N11/02—Enzymes or microbial cells immobilised on or in an organic carrier
    • C12N11/06—Enzymes or microbial cells immobilised on or in an organic carrier attached to the carrier via a bridging agent
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/60—Medicinal preparations containing antigens or antibodies characteristics by the carrier linked to the antigen
    • A61K2039/6087—Polysaccharides; Lipopolysaccharides [LPS]

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Chemistry (AREA)
  • Mycology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Molecular Biology (AREA)
  • Biomedical Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Materials Engineering (AREA)
  • Polymers & Plastics (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
SE7511288A 1967-07-07 1975-10-08 METHOD OF MAKING CONJUGATE OF INSULIN WITH ACIDIC POLYSACCARIDES SE400652B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB31374/67A GB1174854A (en) 1967-07-07 1967-07-07 New Biologically Active Conjugates

Publications (2)

Publication Number Publication Date
SE7511288L SE7511288L (en) 1975-10-08
SE400652B true SE400652B (en) 1978-04-03

Family

ID=10322153

Family Applications (2)

Application Number Title Priority Date Filing Date
SE6809321A SE383100B (en) 1967-07-07 1968-07-05 PROCEDURE FOR THE PREPARATION OF IMMUNOLOGICALLY ACTIVE CONJUGATES OF ALLERGENS OR TOXIC SUBSTANCES
SE7511288A SE400652B (en) 1967-07-07 1975-10-08 METHOD OF MAKING CONJUGATE OF INSULIN WITH ACIDIC POLYSACCARIDES

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE6809321A SE383100B (en) 1967-07-07 1968-07-05 PROCEDURE FOR THE PREPARATION OF IMMUNOLOGICALLY ACTIVE CONJUGATES OF ALLERGENS OR TOXIC SUBSTANCES

Country Status (10)

Country Link
BE (1) BE717689A (en)
CH (1) CH526590A (en)
DE (1) DE1768841C3 (en)
ES (1) ES355853A1 (en)
FR (2) FR1584763A (en)
GB (1) GB1174854A (en)
IL (1) IL30258A (en)
LU (1) LU56423A1 (en)
NL (1) NL160723C (en)
SE (2) SE383100B (en)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4003792A (en) 1967-07-01 1977-01-18 Miles Laboratories, Inc. Conjugates of acid polysaccharides and complex organic substances
GB1243832A (en) * 1968-10-25 1971-08-25 Beecham Group Ltd Vaccines
US3957580A (en) * 1974-03-27 1976-05-18 Pfizer Inc. Immobilized microbial cells
JPS5639022A (en) * 1979-09-05 1981-04-14 Hayashibara Biochem Lab Inc Preparation of vaccine
JPS57136528A (en) * 1981-02-09 1982-08-23 Hayashibara Biochem Lab Inc Preparation of viral vaccine
ATE25708T1 (en) * 1983-06-15 1987-03-15 Gist Brocades Nv BIOLOGICALLY ACTIVE CONJUGATES, THEIR PRODUCTION AND USE.
DE3443877A1 (en) * 1984-06-09 1985-12-12 Hoechst Ag Insulin preparations, process for their preparation, and their use
IT1203814B (en) * 1986-06-30 1989-02-23 Fidia Farmaceutici ESTERS OF ALGINIC ACID
EP0567661A1 (en) * 1992-04-25 1993-11-03 Societe Des Produits Nestle S.A. Modified lipase, method of modification and applications
EP0567662B1 (en) * 1992-04-25 1997-03-05 Societe Des Produits Nestle S.A. Process for aromatizing of milk chocolate
GB2270920B (en) * 1992-09-25 1997-04-02 Univ Keele Alginate-bioactive agent conjugates
FR2817870B1 (en) * 2000-12-08 2006-07-28 Skw Nature Products Holding Fr CONJUGATED POLYMERS BASED ON PECTINES AND THEIR APPLICATION AS EMULSIFIERS

Also Published As

Publication number Publication date
LU56423A1 (en) 1968-10-21
IL30258A (en) 1972-02-29
BE717689A (en) 1968-12-16
SE383100B (en) 1976-03-01
ES355853A1 (en) 1970-03-01
NL160723C (en) 1979-12-17
DE1768841A1 (en) 1971-11-18
DE1768841B2 (en) 1980-01-31
FR7784M (en) 1970-03-23
CH526590A (en) 1972-08-15
NL6809538A (en) 1969-01-09
FR1584763A (en) 1970-01-02
SE7511288L (en) 1975-10-08
GB1174854A (en) 1969-12-17
NL160723B (en) 1979-07-16
DE1768841C3 (en) 1980-09-25

Similar Documents

Publication Publication Date Title
SE409327B (en) METHOD OF PREPARATION OF HOMOPYRIMIDAZOLE DERIVATIVES
CH496176A (en) Dowels
SE393383B (en) WAY TO PRODUCE ADENOSIN DERIVATIVES
SE400652B (en) METHOD OF MAKING CONJUGATE OF INSULIN WITH ACIDIC POLYSACCARIDES
SE412586B (en) SET TO MAKE ISOFLAVON DERIVATIVES
SE385444B (en) METHOD OF ASSEMBLING PARTS USING SHRINK FITTING TECHNIQUES
SE387115B (en) METHOD OF PREPARING NITRO-IMIDAZOLES WITH ANTIMICROBIAL EFFECT
SE382215B (en) WAY TO PRODUCE CHROMANDER DERIVATIVES
SE391181B (en) WAY TO PRODUCE CHINAZOLINE DERIVATIVES
SE373370B (en) METHOD OF MANUFACTUREING L-GUANIDINOTENYL PENICILLINES
CH527376A (en) Dowels
SE385893B (en) METHOD OF PREPARING DIACYLXANTINE DERIVATIVES
SE391337B (en) WAY TO PRODUCE 2-SUBSTITUTED ADENOSIN DERIVATIVES
SE384867B (en) WAY TO PRODUCE 2-SUBSTITUTED ADENOSIN DERIVATIVES
SE382212B (en) METHOD OF PRODUCING DEKAHYDROISOKINOLINE DERIVATIVES
SE417211B (en) SET TO MAKE INDENYL-3-ACETOGLUCURONIDES
SE385981B (en) WAY TO INDICATE THE NERVARENCE OF VANADIN IN AN EARTH FORMATION
SE393982B (en) METHOD OF PREPARING DIHYDROKINOLINE DERIVATIVES WITH ANTIOXIDING EFFECT
SE409546B (en) WAY TO PRODUCE AN INTRAVENOST INJECTIVE GAMMA GLOBULIN SOLUTION
CH481314A (en) Dowel with locking device
SE415884B (en) SET TO MAKE VINKAMON
SE382324B (en) METHODS OF PREPARING AMIDIZED PHENOXIPROPANOLAMINE DERIVATIVES WITH THERAPEUTIC APPLICABILITY
CH524777A (en) Dowels
SE394669B (en) METHOD OF PRODUCING 4-HYDROXYPHENYLGLYCIN
SE390308B (en) WAY TO PRODUCE SUBSTITUTED COBAMIDS