SE387341B - Forfarande for framstellning av 1-aryl-n-dialkyl-aminoalkyl-3,4-dihydro2(h)-isokinolinkarboxamider - Google Patents

Forfarande for framstellning av 1-aryl-n-dialkyl-aminoalkyl-3,4-dihydro2(h)-isokinolinkarboxamider

Info

Publication number
SE387341B
SE387341B SE7409496A SE7409496A SE387341B SE 387341 B SE387341 B SE 387341B SE 7409496 A SE7409496 A SE 7409496A SE 7409496 A SE7409496 A SE 7409496A SE 387341 B SE387341 B SE 387341B
Authority
SE
Sweden
Prior art keywords
isocinolin
dihydro2
carboxamides
aminoalkyl
dialkyl
Prior art date
Application number
SE7409496A
Other languages
English (en)
Swedish (sv)
Other versions
SE7409496L (xx
Inventor
P K Yonan
Original Assignee
Searle & Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Searle & Co filed Critical Searle & Co
Publication of SE7409496L publication Critical patent/SE7409496L/xx
Publication of SE387341B publication Critical patent/SE387341B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/58Radicals substituted by nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals
    • C07D217/16Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals substituted by oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/52Radicals substituted by halogen atoms or nitro radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D319/00Heterocyclic compounds containing six-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D319/101,4-Dioxanes; Hydrogenated 1,4-dioxanes
    • C07D319/141,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems
    • C07D319/161,4-Dioxanes; Hydrogenated 1,4-dioxanes condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D319/18Ethylenedioxybenzenes, not substituted on the hetero ring
SE7409496A 1973-07-23 1974-07-22 Forfarande for framstellning av 1-aryl-n-dialkyl-aminoalkyl-3,4-dihydro2(h)-isokinolinkarboxamider SE387341B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US381505A US3905982A (en) 1973-07-23 1973-07-23 1-Aryl-n-dialkylaminoalkyl-3,4-dihydro-2(1H)-isoquinolinecarboxamides and related compounds

Publications (2)

Publication Number Publication Date
SE7409496L SE7409496L (xx) 1975-01-24
SE387341B true SE387341B (sv) 1976-09-06

Family

ID=23505299

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7409496A SE387341B (sv) 1973-07-23 1974-07-22 Forfarande for framstellning av 1-aryl-n-dialkyl-aminoalkyl-3,4-dihydro2(h)-isokinolinkarboxamider

Country Status (17)

Country Link
US (1) US3905982A (xx)
JP (1) JPS5041873A (xx)
AR (2) AR202416A1 (xx)
AT (1) AT329563B (xx)
BE (1) BE817917A (xx)
CA (1) CA1041501A (xx)
CH (2) CH605774A5 (xx)
DE (1) DE2435168A1 (xx)
DK (1) DK138644B (xx)
ES (2) ES428503A1 (xx)
FR (1) FR2238488B1 (xx)
GB (1) GB1452398A (xx)
IE (1) IE39630B1 (xx)
NL (1) NL7409881A (xx)
NO (1) NO141160C (xx)
SE (1) SE387341B (xx)
ZA (1) ZA744665B (xx)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8518634D0 (en) * 1985-07-23 1985-08-29 Smithkline Beckman Corp Chemical compounds
DK8386A (da) * 1986-01-15 1987-07-09 Tpo Pharmachim Nye n-substituerede 1-benzyl-2-carbamoyltetrahydroisoquinoliner og fremgangsmaade til fremstilling af samme
JP2577215B2 (ja) * 1987-01-16 1997-01-29 化研生薬株式会社 ベンジルイソキノリン誘導体
US6376670B1 (en) 1997-06-19 2002-04-23 Sepracor Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6103905A (en) * 1997-06-19 2000-08-15 Sepracor, Inc. Quinoline-indole antimicrobial agents, uses and compositions related thereto
US6207679B1 (en) 1997-06-19 2001-03-27 Sepracor, Inc. Antimicrobial agents uses and compositions related thereto
JP2002505689A (ja) 1997-06-19 2002-02-19 セプレイコー インコーポレイテッド キノリン−インドール抗菌剤、それらに関する用途及び組成物
US6858147B2 (en) * 2001-08-03 2005-02-22 Dispersion Technology, Inc. Method for the removal of heavy metals from aqueous solution by means of silica as an adsorbent in counter-flow selective dialysis
US20060229524A1 (en) * 2005-04-08 2006-10-12 Alden Ozment Method for the accurate placement of EKG electrodes
EP3763711A1 (en) * 2019-07-09 2021-01-13 Allinky Biopharma Tetrahydroisoquinoline compounds

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3524858A (en) * 1967-05-18 1970-08-18 Warner Lambert Pharmaceutical 1,4 - dihydro-1-substituted alkyl-6,7-methylenedioxy - 4 - oxoquinoline-3-carboxylic acid
US3483206A (en) * 1967-12-15 1969-12-09 Ciba Geigy Corp N-isoquinolylalkanoyl-n-arylamines
US3634429A (en) * 1969-09-30 1972-01-11 Hoffmann La Roche Morphinan derivatives and preparation thereof
US3666763A (en) * 1970-01-06 1972-05-30 Hoffmann La Roche 4-phenyl isoquinolines and process for preparing same

Also Published As

Publication number Publication date
DK395174A (xx) 1975-03-10
AR202416A1 (es) 1975-06-06
BE817917A (fr) 1975-01-22
US3905982A (en) 1975-09-16
JPS5041873A (xx) 1975-04-16
FR2238488B1 (xx) 1978-06-30
AR205380A1 (es) 1976-04-30
ES428503A1 (es) 1976-12-16
ATA602874A (de) 1975-08-15
CA1041501A (en) 1978-10-31
DK138644B (da) 1978-10-09
ZA744665B (en) 1975-09-24
CH605774A5 (xx) 1978-10-13
SE7409496L (xx) 1975-01-24
CH605773A5 (xx) 1978-10-13
AU7147074A (en) 1976-01-22
DE2435168A1 (de) 1975-02-06
NO141160B (no) 1979-10-15
DK138644C (xx) 1979-03-19
GB1452398A (en) 1976-10-13
AT329563B (de) 1976-05-25
IE39630L (en) 1975-01-23
FR2238488A1 (xx) 1975-02-21
NO141160C (no) 1980-01-23
ES448973A1 (es) 1977-11-16
NL7409881A (nl) 1975-01-27
NO742679L (xx) 1975-01-24
IE39630B1 (en) 1978-11-22

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