SE383513B - Forfarande for framstellning av i stellningarna 7 och 15 ev. substituerade prostaglandinestrar och fria syror av typ 3-oxa-pga med blodtryckssenkande egenskaper. - Google Patents

Forfarande for framstellning av i stellningarna 7 och 15 ev. substituerade prostaglandinestrar och fria syror av typ 3-oxa-pga med blodtryckssenkande egenskaper.

Info

Publication number
SE383513B
SE383513B SE7010366A SE1036670A SE383513B SE 383513 B SE383513 B SE 383513B SE 7010366 A SE7010366 A SE 7010366A SE 1036670 A SE1036670 A SE 1036670A SE 383513 B SE383513 B SE 383513B
Authority
SE
Sweden
Prior art keywords
prostaglandinesters
pga
oxa
substituted
procedure
Prior art date
Application number
SE7010366A
Other languages
English (en)
Swedish (sv)
Inventor
N A Nelson
Original Assignee
Upjohn Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Upjohn Co filed Critical Upjohn Co
Publication of SE383513B publication Critical patent/SE383513B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0016—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing only hydroxy, etherified or esterified hydroxy groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C35/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring
    • C07C35/22—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system
    • C07C35/23—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings
    • C07C35/27—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a ring other than a six-membered aromatic ring polycyclic, at least one hydroxy group bound to a condensed ring system with hydroxy on a condensed ring system having two rings the condensed ring system containing six carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C405/00—Compounds containing a five-membered ring having two side-chains in ortho position to each other, and having oxygen atoms directly attached to the ring in ortho position to one of the side-chains, one side-chain containing, not directly attached to the ring, a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, and the other side-chain having oxygen atoms attached in gamma-position to the ring, e.g. prostaglandins ; Analogues or derivatives thereof
    • C07C405/0008—Analogues having the carboxyl group in the side-chains replaced by other functional groups
    • C07C405/0025—Analogues having the carboxyl group in the side-chains replaced by other functional groups containing keto groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
    • C07D309/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
    • C07D309/08—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D309/10—Oxygen atoms
    • C07D309/12—Oxygen atoms only hydrogen atoms and one oxygen atom directly attached to ring carbon atoms, e.g. tetrahydropyranyl ethers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/30—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Pyrane Compounds (AREA)
SE7010366A 1969-07-29 1970-07-28 Forfarande for framstellning av i stellningarna 7 och 15 ev. substituerade prostaglandinestrar och fria syror av typ 3-oxa-pga med blodtryckssenkande egenskaper. SE383513B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB38073/69A GB1269657A (en) 1969-07-29 1969-07-29 Prostaglandin analogues, their preparation and pharmaceutical compositions containing them

Publications (1)

Publication Number Publication Date
SE383513B true SE383513B (sv) 1976-03-15

Family

ID=10400988

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7010366A SE383513B (sv) 1969-07-29 1970-07-28 Forfarande for framstellning av i stellningarna 7 och 15 ev. substituerade prostaglandinestrar och fria syror av typ 3-oxa-pga med blodtryckssenkande egenskaper.

Country Status (10)

Country Link
JP (2) JPS5028950B1 (pt)
BE (1) BE754114A (pt)
CH (2) CH571486A5 (pt)
DE (1) DE2036471A1 (pt)
FR (1) FR2059574B1 (pt)
GB (1) GB1269657A (pt)
HU (2) HU162687B (pt)
NL (1) NL7010617A (pt)
SE (1) SE383513B (pt)
ZA (1) ZA704099B (pt)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3920724A (en) * 1969-07-29 1975-11-18 Upjohn Co 4-oxa prostaglandin f ' -type compounds
US3923865A (en) * 1969-07-29 1975-12-02 Upjohn Co 4-Oxa prostaglandin F{62 -type compounds
US3923861A (en) * 1969-07-29 1975-12-02 Upjohn Co 3-Oxa prostaglandin F{331 -type compounds
US3944593A (en) * 1969-07-29 1976-03-16 The Upjohn Company 3-Oxa prostaglandin E-type compounds
US3920723A (en) * 1969-07-29 1975-11-18 Upjohn Co 4-oxaprostaglandin e-type compounds
US3922298A (en) * 1969-07-29 1975-11-25 Upjohn Co 3-Oxa prostaglandin B-type compounds
US3923864A (en) * 1969-07-29 1975-12-02 Upjohn Co 3-Oxa prostaglandin A-type compounds
US3923862A (en) * 1969-07-29 1975-12-02 Upjohn Co 4-Oxa prostaglandin {62 -type compounds
US3923863A (en) * 1969-07-29 1975-12-02 Upjohn Co 4-Oxa prostaglandin A-type compounds
US3936487A (en) * 1970-06-17 1976-02-03 The Upjohn Company 3-Oxa prostaglandin Fα-type compounds
DE2258668C3 (de) * 1971-12-03 1981-08-06 Syntex Corp., Panama-City Neue Prostaglandine, Verfahren zu deren Herstellung und diese enthaltende Arzneimittel
US4001296A (en) * 1973-05-21 1977-01-04 The Upjohn Company 5-Oxa prostaglandin E1 analogs
US3980692A (en) * 1973-05-21 1976-09-14 The Upjohn Company 5-Oxa-17,18-dehydroprostaglandin-E1 -type analogs
US3931279A (en) * 1973-05-21 1976-01-06 The Upjohn Company 5-Oxa prostaglandin F2.sub.α analogs
US3981902A (en) * 1973-05-21 1976-09-21 The Upjohn Company 5-Oxa-17,18-dehydroprostaglandin-F1.sub.α -type analogs
JPS5215047U (pt) * 1975-07-22 1977-02-02
JPS5235356A (en) * 1975-09-13 1977-03-17 Toyo Seisakusho:Kk Manufacturing method of heat recovery device using heat pipe
US4181725A (en) * 1977-05-02 1980-01-01 The Regents Of The University Of Michigan Method for alleviating psoriasis
JPS5491311U (pt) * 1977-12-10 1979-06-28
JPS60238552A (ja) * 1984-05-09 1985-11-27 日本軽金属株式会社 カ−テンウオ−ル
US5891910A (en) * 1987-07-17 1999-04-06 Schering Aktiengesellschaft 9-halogen-(Z) prostaglandin derivatives, process for their production and their use as pharmaceutical agents
JP2716986B2 (ja) 1987-07-17 1998-02-18 シエーリング アクチエンゲゼルシヤフト ９‐ハロゲン‐（ｚ）‐プロスタグランジン誘導体、その製法及び薬剤としてのその使用
JPS6443107U (pt) * 1987-09-08 1989-03-15
JPH0380812U (pt) * 1989-08-16 1991-08-19

Also Published As

Publication number Publication date
FR2059574A1 (pt) 1971-06-04
NL7010617A (pt) 1971-02-02
HU162688B (pt) 1973-03-28
ZA704099B (en) 1971-03-31
BE754114A (fr) 1971-01-29
JPS503311B1 (pt) 1975-02-03
GB1269657A (en) 1972-04-06
JPS5028950B1 (pt) 1975-09-19
HU162687B (pt) 1973-03-28
CH571486A5 (pt) 1976-01-15
FR2059574B1 (pt) 1974-03-22
DE2036471A1 (pt) 1971-02-11
CH571487A5 (pt) 1976-01-15

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