SE341399B - - Google Patents

Info

Publication number
SE341399B
SE341399B SE15415/65A SE1541565A SE341399B SE 341399 B SE341399 B SE 341399B SE 15415/65 A SE15415/65 A SE 15415/65A SE 1541565 A SE1541565 A SE 1541565A SE 341399 B SE341399 B SE 341399B
Authority
SE
Sweden
Application number
SE15415/65A
Inventor
H Schoeler
E Reerink
P Westerhof
Original Assignee
Philips Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Philips Nv filed Critical Philips Nv
Publication of SE341399B publication Critical patent/SE341399B/xx

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A61K31/573—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone substituted in position 21, e.g. cortisone, dexamethasone, prednisone or aldosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/5685—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone having an oxo group in position 17, e.g. androsterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/565—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol
    • A61K31/568—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone
    • A61K31/569—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids not substituted in position 17 beta by a carbon atom, e.g. estrane, estradiol substituted in positions 10 and 13 by a chain having at least one carbon atom, e.g. androstanes, e.g. testosterone substituted in position 17 alpha, e.g. ethisterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/575—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of three or more carbon atoms, e.g. cholane, cholestane, ergosterol, sitosterol
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J15/00—Stereochemically pure steroids containing carbon, hydrogen, halogen or oxygen having a partially or totally inverted skeleton, e.g. retrosteroids, L-isomers
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J9/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of more than two carbon atoms, e.g. cholane, cholestane, coprostane

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Conveying And Assembling Of Building Elements In Situ (AREA)
SE15415/65A 1958-04-12 1965-11-29 SE341399B (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
NL226774 1958-04-12
NL232312 1958-10-15
NL236884 1959-03-07

Publications (1)

Publication Number Publication Date
SE341399B true SE341399B (de) 1971-12-27

Family

ID=27351008

Family Applications (9)

Application Number Title Priority Date Filing Date
SE3390/59A SE342814B (de) 1958-04-12 1959-04-09
SE15412/65A SE341401B (de) 1958-04-12 1965-11-29
SE15410/65A SE341397B (de) 1958-04-12 1965-11-29
SE15413/65A SE341398B (de) 1958-04-12 1965-11-29
SE15411/65A SE341400B (de) 1958-04-12 1965-11-29
SE15415/65A SE341399B (de) 1958-04-12 1965-11-29
SE15416/65A SE341848B (de) 1958-04-12 1965-11-29
SE15414/65A SE341394B (de) 1958-04-12 1965-11-29
SE15417/65A SE342445B (de) 1958-04-12 1965-11-29

Family Applications Before (5)

Application Number Title Priority Date Filing Date
SE3390/59A SE342814B (de) 1958-04-12 1959-04-09
SE15412/65A SE341401B (de) 1958-04-12 1965-11-29
SE15410/65A SE341397B (de) 1958-04-12 1965-11-29
SE15413/65A SE341398B (de) 1958-04-12 1965-11-29
SE15411/65A SE341400B (de) 1958-04-12 1965-11-29

Family Applications After (3)

Application Number Title Priority Date Filing Date
SE15416/65A SE341848B (de) 1958-04-12 1965-11-29
SE15414/65A SE341394B (de) 1958-04-12 1965-11-29
SE15417/65A SE342445B (de) 1958-04-12 1965-11-29

Country Status (13)

Country Link
US (4) US3192201A (de)
AT (2) AT287213B (de)
CH (14) CH455765A (de)
CS (2) CS149567B2 (de)
DE (1) DE1253707B (de)
DK (7) DK110201C (de)
ES (1) ES248593A1 (de)
FI (2) FI42083B (de)
FR (1) FR953M (de)
GB (5) GB929279A (de)
NO (1) NO122835B (de)
OA (1) OA02640A (de)
SE (9) SE342814B (de)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH455765A (de) * 1958-04-12 1968-05-15 Philips Nv Verfahren zur Herstellung neuer Steroide
BE634693A (de) * 1962-07-10
US3235573A (en) * 1962-12-20 1966-02-15 Syntex Corp 19-lower alkylidene and 19-oxo-delta4-androsten-17beta-ol-3-one derivatives
NL123937C (de) * 1963-11-06
US3463852A (en) * 1966-01-14 1969-08-26 Schering Corp Treating allergies with steroids of the pregnane series
CH481904A (de) * 1966-06-10 1969-11-30 Hoffmann La Roche Verfahren zur Herstellung von neuen 9B, 10a-Steroiden
GB1266361A (de) * 1969-07-16 1972-03-08
US5922699A (en) * 1996-06-07 1999-07-13 Pherin Corporation 19-nor-cholane steroids as neurochemical initiators of change in human hypothalamic function
CN113880904B (zh) * 2020-07-01 2024-04-12 苏州朗科生物技术股份有限公司 合成地屈孕酮的新方法及化合物
CN114057820B (zh) * 2021-11-15 2023-06-27 湖南科瑞生物制药股份有限公司 一种地屈孕酮的精制方法
CN114957370B (zh) * 2021-12-06 2023-09-19 湖南醇康医药科技有限公司 一种地屈孕酮的制备和纯化方法
CN114957369B (zh) * 2021-12-07 2023-10-31 湖南醇康医药科技有限公司 一种地屈孕酮的制备方法

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE882399C (de) * 1937-11-28 1953-07-09 Schering Ag Verfahren zur Darstellung von 17-AEthinyl-?-androstenol-17-on-3 und dessen Derivaten
US2752337A (en) * 1951-06-28 1956-06-26 Upjohn Co Steroid enamines
US2739974A (en) * 1953-04-06 1956-03-27 Searle & Co Process of preparing delta4,6-3-ketosteroids
US2871245A (en) * 1956-06-19 1959-01-27 Ciba Pharm Prod Inc New 1-dehydro-testosterones and esters thereof
US2867630A (en) * 1958-06-09 1959-01-06 Upjohn Co 6-fluoro androstenes
CH455765A (de) * 1958-04-12 1968-05-15 Philips Nv Verfahren zur Herstellung neuer Steroide
GB956691A (en) * 1961-10-05 1964-04-29 British Drug Houses Ltd 3-unsubstituted-í¸-androstene compounds

Also Published As

Publication number Publication date
CH415615A (de) 1966-06-30
CH420131A (de) 1966-09-15
SE341397B (de) 1971-12-27
AT281307B (de) 1970-05-25
CH455765A (de) 1968-05-15
CH420130A (de) 1966-09-15
CH415614A (de) 1966-06-30
CS161826B2 (de) 1975-06-10
SE341398B (de) 1971-12-27
CH464183A (de) 1968-10-31
NO122835B (de) 1971-08-23
OA02640A (fr) 1970-12-15
DK110201C (da) 1970-11-30
DK108571C (da) 1968-01-08
GB929278A (en) 1963-06-19
US3445489A (en) 1969-05-20
CS149567B2 (de) 1973-07-25
FR953M (de) 1961-11-27
CH432505A (de) 1967-03-31
SE342814B (de) 1972-02-21
GB929271A (en) 1963-06-19
DK115038B (da) 1969-09-01
SE341394B (de) 1971-12-27
DK124079B (da) 1972-09-11
CH415613A (de) 1966-06-30
ES248593A1 (es) 1959-11-16
SE341400B (de) 1971-12-27
FI42212B (de) 1970-03-02
US3362968A (en) 1968-01-09
CH434244A (de) 1967-04-30
US3192201A (en) 1965-06-29
SE341401B (de) 1971-12-27
DE1253707B (de) 1967-11-09
GB929276A (en) 1963-06-19
DK103510C (da) 1966-01-17
SE342445B (de) 1972-02-07
CH432506A (de) 1967-03-31
SE341848B (de) 1972-01-17
CH416612A (de) 1966-07-15
US3373172A (en) 1968-03-12
GB929277A (en) 1963-06-19
DK107871C (da) 1967-07-17
FI42083B (de) 1970-02-02
AT287213B (de) 1971-01-11
GB929279A (en) 1963-06-19
CH428720A (de) 1967-01-31
DK118503B (da) 1970-08-31
CH441299A (de) 1967-08-15
CH430710A (de) 1967-02-28

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