SE337214B - - Google Patents

Info

Publication number
SE337214B
SE337214B SE15400/66A SE1540066A SE337214B SE 337214 B SE337214 B SE 337214B SE 15400/66 A SE15400/66 A SE 15400/66A SE 1540066 A SE1540066 A SE 1540066A SE 337214 B SE337214 B SE 337214B
Authority
SE
Sweden
Prior art keywords
formula
compounds
radical
alkyl
compound
Prior art date
Application number
SE15400/66A
Inventor
J Kollonitsch
R Tull
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Publication of SE337214B publication Critical patent/SE337214B/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C211/00Compounds containing amino groups bound to a carbon skeleton
    • C07C211/01Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms
    • C07C211/16Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings
    • C07C211/19Compounds containing amino groups bound to a carbon skeleton having amino groups bound to acyclic carbon atoms of a saturated carbon skeleton containing rings other than six-membered aromatic rings containing condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F11/00Compounds containing elements of Groups 6 or 16 of the Periodic Table
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Fluidized-Bed Combustion And Resonant Combustion (AREA)

Abstract

The invention comprises compounds of the Formulae I and II, wherein R* represents an alkyl, aryl or aralkyl radical and each of X and X1 is a hydrogen or halogen atom, or a C1- 6 alkyl, trifluoromethyl, hydroxy, C1- 4 alkoxy, C1- 4 alkylmercapto, C1- 4 alkylsulphonyl or C2- 8 dialkylsulphamoyl radical; processes for preparing compounds of the Formula I by reacting compounds of the Formula III with hydrogen in the presence of a hydrogenation catalyst or by hydrolysing compounds of the Formula IV to produce 5-methylaminopropyl-10,11-dihydro-5H-dibenzocycloheptenes of the Formula V and acylating the latter with acylating agents derived from alkanoic; aralkanoic or aroic acids; and a process for preparing compounds of the Formula II by dehydrogenating compounds of the Formula I and where, when in the above process, a halogen-containing dehydrogenating agent is used, the product consists of a mixture of compounds of the Formula II with compounds of the Formula IX where Y represents a halogen atom, said mixture is treated with a tertiary amine, and the process in which a compound of the Formula II is hydrolysed to give a 5-methylaminopropyl - 5H - dibenzo[a,d] cycloheptene of the Formula VI. <FORM:1055469/C2/1> <FORM:1055469/C2/2> <FORM:1055469/C2/3> <FORM:1055469/C2/4> <FORM:1055469/C2/5> <FORM:1055469/C2/6> <FORM:1055469/C2/7> <FORM:1055469/C2/8> <FORM:1055469/C2/9> Urethanes of the Formula IV may be prepared by hydrogenating a compound of the Formula VII, wherein R** represents an alkyl or aryl radical, in the presence of a hydrogenation catalyst, or by hydrogenating a compound of the Formula VIII to give the corresponding 5 - (dimethylaminopropyl) - 10,11 - dihydro - 5H - dibenzo[a,d]cycloheptane and reacting the latter with a haloformate of the formula X0COR0, wherein X0 represents a halogen atom and R0 represents an aralkoxy radical.
SE15400/66A 1962-07-17 1966-11-10 SE337214B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US21058962A 1962-07-17 1962-07-17

Publications (1)

Publication Number Publication Date
SE337214B true SE337214B (en) 1971-08-02

Family

ID=22783487

Family Applications (3)

Application Number Title Priority Date Filing Date
SE7578/63A SE320063B (en) 1962-07-17 1963-07-08
SE15400/66A SE337214B (en) 1962-07-17 1966-11-10
SE15399/66A SE337213B (en) 1962-07-17 1966-11-10

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE7578/63A SE320063B (en) 1962-07-17 1963-07-08

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE15399/66A SE337213B (en) 1962-07-17 1966-11-10

Country Status (9)

Country Link
AT (1) AT252898B (en)
BR (1) BR6350842D0 (en)
CH (1) CH453341A (en)
DE (1) DE1468272A1 (en)
DK (3) DK108253C (en)
FI (2) FI41740B (en)
GB (1) GB1055469A (en)
NO (1) NO120835B (en)
SE (3) SE320063B (en)

Also Published As

Publication number Publication date
AT252898B (en) 1967-03-10
DK108253C (en) 1967-10-30
DK108210C (en) 1967-10-16
SE320063B (en) 1970-02-02
SE337213B (en) 1971-08-02
BR6350842D0 (en) 1973-07-12
CH453341A (en) 1968-06-14
FI42828B (en) 1970-08-03
NO120835B (en) 1970-12-14
DE1468272A1 (en) 1968-12-19
FI41740B (en) 1969-10-31
DK116730B (en) 1970-02-09
GB1055469A (en) 1967-01-18

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