SE331336B - - Google Patents
Info
- Publication number
- SE331336B SE331336B SE627361A SE627361A SE331336B SE 331336 B SE331336 B SE 331336B SE 627361 A SE627361 A SE 627361A SE 627361 A SE627361 A SE 627361A SE 331336 B SE331336 B SE 331336B
- Authority
- SE
- Sweden
- Prior art keywords
- sulphate
- copper
- chloride
- acetate
- callicrein
- Prior art date
Links
- 102000001399 Kallikrein Human genes 0.000 abstract 2
- 108060005987 Kallikrein Proteins 0.000 abstract 2
- VSCWAEJMTAWNJL-UHFFFAOYSA-K aluminium trichloride Chemical compound Cl[Al](Cl)Cl VSCWAEJMTAWNJL-UHFFFAOYSA-K 0.000 abstract 2
- -1 alums Chemical compound 0.000 abstract 2
- 230000000937 inactivator Effects 0.000 abstract 2
- 150000003839 salts Chemical class 0.000 abstract 2
- 229910021578 Iron(III) chloride Inorganic materials 0.000 abstract 1
- 229910021380 Manganese Chloride Inorganic materials 0.000 abstract 1
- GLFNIEUTAYBVOC-UHFFFAOYSA-L Manganese chloride Chemical compound Cl[Mn]Cl GLFNIEUTAYBVOC-UHFFFAOYSA-L 0.000 abstract 1
- ZOIORXHNWRGPMV-UHFFFAOYSA-N acetic acid;zinc Chemical compound [Zn].CC(O)=O.CC(O)=O ZOIORXHNWRGPMV-UHFFFAOYSA-N 0.000 abstract 1
- 229910052783 alkali metal Inorganic materials 0.000 abstract 1
- 150000001340 alkali metals Chemical class 0.000 abstract 1
- 229910052784 alkaline earth metal Inorganic materials 0.000 abstract 1
- 150000001342 alkaline earth metals Chemical class 0.000 abstract 1
- 239000001164 aluminium sulphate Substances 0.000 abstract 1
- 235000011128 aluminium sulphate Nutrition 0.000 abstract 1
- 210000001557 animal structure Anatomy 0.000 abstract 1
- 239000007864 aqueous solution Substances 0.000 abstract 1
- ODWXUNBKCRECNW-UHFFFAOYSA-M bromocopper(1+) Chemical compound Br[Cu+] ODWXUNBKCRECNW-UHFFFAOYSA-M 0.000 abstract 1
- ORTQZVOHEJQUHG-UHFFFAOYSA-L copper(II) chloride Chemical compound Cl[Cu]Cl ORTQZVOHEJQUHG-UHFFFAOYSA-L 0.000 abstract 1
- XTVVROIMIGLXTD-UHFFFAOYSA-N copper(II) nitrate Chemical compound [Cu+2].[O-][N+]([O-])=O.[O-][N+]([O-])=O XTVVROIMIGLXTD-UHFFFAOYSA-N 0.000 abstract 1
- ARUVKPQLZAKDPS-UHFFFAOYSA-L copper(II) sulfate Chemical compound [Cu+2].[O-][S+2]([O-])([O-])[O-] ARUVKPQLZAKDPS-UHFFFAOYSA-L 0.000 abstract 1
- OPQARKPSCNTWTJ-UHFFFAOYSA-L copper(ii) acetate Chemical compound [Cu+2].CC([O-])=O.CC([O-])=O OPQARKPSCNTWTJ-UHFFFAOYSA-L 0.000 abstract 1
- BUACSMWVFUNQET-UHFFFAOYSA-H dialuminum;trisulfate;hydrate Chemical compound O.[Al+3].[Al+3].[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O.[O-]S([O-])(=O)=O BUACSMWVFUNQET-UHFFFAOYSA-H 0.000 abstract 1
- 238000000605 extraction Methods 0.000 abstract 1
- 239000011790 ferrous sulphate Substances 0.000 abstract 1
- 235000003891 ferrous sulphate Nutrition 0.000 abstract 1
- RBTARNINKXHZNM-UHFFFAOYSA-K iron trichloride Chemical compound Cl[Fe](Cl)Cl RBTARNINKXHZNM-UHFFFAOYSA-K 0.000 abstract 1
- 229940046892 lead acetate Drugs 0.000 abstract 1
- RLJMLMKIBZAXJO-UHFFFAOYSA-N lead nitrate Chemical compound [O-][N+](=O)O[Pb]O[N+]([O-])=O RLJMLMKIBZAXJO-UHFFFAOYSA-N 0.000 abstract 1
- 239000011565 manganese chloride Substances 0.000 abstract 1
- 235000002867 manganese chloride Nutrition 0.000 abstract 1
- 229940099607 manganese chloride Drugs 0.000 abstract 1
- 239000011702 manganese sulphate Substances 0.000 abstract 1
- 235000007079 manganese sulphate Nutrition 0.000 abstract 1
- SQQMAOCOWKFBNP-UHFFFAOYSA-L manganese(II) sulfate Chemical compound [Mn+2].[O-]S([O-])(=O)=O SQQMAOCOWKFBNP-UHFFFAOYSA-L 0.000 abstract 1
- 229910052751 metal Inorganic materials 0.000 abstract 1
- 239000002184 metal Substances 0.000 abstract 1
- 150000002739 metals Chemical class 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 230000004048 modification Effects 0.000 abstract 1
- 238000012986 modification Methods 0.000 abstract 1
- 239000000243 solution Substances 0.000 abstract 1
- 239000004246 zinc acetate Substances 0.000 abstract 1
- NWONKYPBYAMBJT-UHFFFAOYSA-L zinc sulfate Chemical compound [Zn+2].[O-]S([O-])(=O)=O NWONKYPBYAMBJT-UHFFFAOYSA-L 0.000 abstract 1
- 239000011686 zinc sulphate Substances 0.000 abstract 1
- 235000009529 zinc sulphate Nutrition 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/81—Protease inhibitors
- C07K14/8107—Endopeptidase (E.C. 3.4.21-99) inhibitors
- C07K14/811—Serine protease (E.C. 3.4.21) inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/55—Protease inhibitors
- A61K38/57—Protease inhibitors from animals; from humans
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Gastroenterology & Hepatology (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Zoology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Extraction Or Liquid Replacement (AREA)
- Fodder In General (AREA)
Abstract
A modification of the process for producing pure solutions of callicrein inactivator according to the parent Specification is characterized in that for the extraction of the callicrein inactivator from animal organs there are used aqueous solutions of salts of metals other than alkaline earth metals or alkali metals. Specified salts are copper chloride, copper bromide, copper sulphate, copper acetate, copper nitrate, zinc sulphate, zinc acetate, aluminium chloride, aluminium sulphate, alums, lead nitrate, lead acetate, manganese sulphate, manganese chloride, ferric chloride or ferrous sulphate.
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DEF28061A DE1084433B (en) | 1959-03-28 | 1959-03-28 | Process for the production of pure solutions of the kallikrein inactivator |
| DEF31463A DE1148352B (en) | 1959-03-28 | 1960-06-18 | Process for the production of pure solutions of the kallikrein inactivator |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE331336B true SE331336B (en) | 1970-12-21 |
Family
ID=25974261
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE627361A SE331336B (en) | 1959-03-28 | 1961-06-15 |
Country Status (6)
| Country | Link |
|---|---|
| CH (1) | CH426104A (en) |
| DE (1) | DE1148352B (en) |
| FR (1) | FR80105E (en) |
| GB (1) | GB916932A (en) |
| NL (2) | NL140409B (en) |
| SE (1) | SE331336B (en) |
-
0
- NL NL266078D patent/NL266078A/xx unknown
-
1960
- 1960-06-18 DE DEF31463A patent/DE1148352B/en active Pending
-
1961
- 1961-05-19 CH CH587261A patent/CH426104A/en unknown
- 1961-06-12 GB GB2117761A patent/GB916932A/en not_active Expired
- 1961-06-15 SE SE627361A patent/SE331336B/xx unknown
- 1961-06-16 FR FR865230A patent/FR80105E/en not_active Expired
- 1961-06-16 NL NL266078A patent/NL140409B/en unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB916932A (en) | 1963-01-30 |
| NL266078A (en) | |
| FR80105E (en) | 1963-03-15 |
| NL140409B (en) | 1973-12-17 |
| CH426104A (en) | 1966-12-15 |
| DE1148352B (en) | 1963-05-09 |
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