SE328278B - - Google Patents
Info
- Publication number
- SE328278B SE328278B SE07807/65A SE780765A SE328278B SE 328278 B SE328278 B SE 328278B SE 07807/65 A SE07807/65 A SE 07807/65A SE 780765 A SE780765 A SE 780765A SE 328278 B SE328278 B SE 328278B
- Authority
- SE
- Sweden
- Prior art keywords
- prepared
- octane
- alkyl
- carboxylic acid
- acid chloride
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C13/00—Cyclic hydrocarbons containing rings other than, or in addition to, six-membered aromatic rings
- C07C13/28—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof
- C07C13/32—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with condensed rings
- C07C13/44—Polycyclic hydrocarbons or acyclic hydrocarbon derivatives thereof with condensed rings with a bicyclo ring system containing eight carbon atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Cephalosporin Compounds (AREA)
Abstract
Novel compounds of formula <FORM:1079592/C2/1> where R is H or C1-C6 alkyl, X and Y are each hydrogen, methyl or ethyl and R1 is -NR2R3 where R2 and R3 are each hydrogen, alkyl of 1 to 6 carbon atoms or allyl, and acid addition salts thereof, are prepared by reduction of the corresponding carboxamide or a bicyclo-[2,2,2]-octyl-(1) alkyl ketone oxime or by reaction of acetonitrile with an a ,a -dialkylbicyclo-(2,2,2)-octane-1-methanol, in each case optionally followed by alkylation of the amine group and/or salt formation. 4 - Alkylbicyclo - [2,2,2] - octane - 1 - carboxamides are prepared by reaction of ammonia or an appropriate amine with the corresponding acid chloride which is itself prepared from the carboxylic acid. The above oximes are prepared in the usual manner from the bicyclo-[2,2,2]-octyl-(1)-alkyl ketone which is itself prepared from an organometallic compound and the 1-carboxylic acid chloride. a ,a - Dimethylbicyclo - [2,2,2] - octane - 1-methanol is prepared by action of methylmagnesium bromide on the 1-carboxylic acid chloride. Penicillin salts of the above novel compounds are disclosed. Pharmaceutical compositions, feed concentrates and foodstuffs comprise an above novel compound and a carrier therefor.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US37533764A | 1964-06-15 | 1964-06-15 |
Publications (1)
Publication Number | Publication Date |
---|---|
SE328278B true SE328278B (en) | 1970-09-14 |
Family
ID=23480493
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
SE07807/65A SE328278B (en) | 1964-06-15 | 1965-06-14 |
Country Status (14)
Country | Link |
---|---|
AT (3) | AT271423B (en) |
BE (1) | BE665459A (en) |
BR (1) | BR6570006D0 (en) |
CH (1) | CH471070A (en) |
ES (1) | ES314105A1 (en) |
FI (1) | FI43071B (en) |
FR (2) | FR1468715A (en) |
GB (1) | GB1079592A (en) |
IL (1) | IL23726A (en) |
LU (1) | LU48845A1 (en) |
MY (1) | MY6900002A (en) |
NL (1) | NL6507578A (en) |
NO (1) | NO116717B (en) |
SE (1) | SE328278B (en) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3439100A (en) * | 1966-08-09 | 1969-04-15 | Smithkline Corp | Preventing influenza infections with bicyclo(2.2.2)octane-2-methylamine |
US3489802A (en) * | 1967-01-23 | 1970-01-13 | Du Pont | Preparation of alpha-methyl-1-adamantane-methylamine and alpha,4 - dimethyl - 1 - bicyclo(2,2,2)octane methylamine |
EP4055024A1 (en) * | 2019-11-06 | 2022-09-14 | Eastman Chemical Company | Process for preparing bicyclo[2.2.2]octane-1,4-diol |
-
1965
- 1965-05-28 BR BR170006/65A patent/BR6570006D0/en unknown
- 1965-06-10 CH CH808765A patent/CH471070A/en not_active IP Right Cessation
- 1965-06-10 AT AT524665A patent/AT271423B/en active
- 1965-06-10 AT AT71567A patent/AT271428B/en active
- 1965-06-10 AT AT71467A patent/AT271427B/en active
- 1965-06-11 GB GB24804/65A patent/GB1079592A/en not_active Expired
- 1965-06-11 ES ES0314105A patent/ES314105A1/en not_active Expired
- 1965-06-14 FI FI1409/65A patent/FI43071B/fi active
- 1965-06-14 NL NL6507578A patent/NL6507578A/xx unknown
- 1965-06-14 FR FR20734A patent/FR1468715A/en not_active Expired
- 1965-06-14 SE SE07807/65A patent/SE328278B/xx unknown
- 1965-06-14 NO NO158473A patent/NO116717B/no unknown
- 1965-06-14 IL IL23726A patent/IL23726A/en unknown
- 1965-06-15 BE BE665459D patent/BE665459A/xx unknown
- 1965-06-15 LU LU48845A patent/LU48845A1/xx unknown
- 1965-09-13 FR FR31262A patent/FR5324M/fr not_active Expired
-
1969
- 1969-12-31 MY MY19692A patent/MY6900002A/en unknown
Also Published As
Publication number | Publication date |
---|---|
BE665459A (en) | 1965-12-15 |
FI43071B (en) | 1970-10-01 |
AT271423B (en) | 1969-06-10 |
BR6570006D0 (en) | 1973-09-18 |
FR1468715A (en) | 1967-02-10 |
LU48845A1 (en) | 1965-08-17 |
AT271427B (en) | 1969-06-10 |
ES314105A1 (en) | 1966-02-16 |
MY6900002A (en) | 1969-12-31 |
NO116717B (en) | 1969-05-12 |
DE1468813A1 (en) | 1969-01-09 |
GB1079592A (en) | 1967-08-16 |
AT271428B (en) | 1969-06-10 |
IL23726A (en) | 1969-09-25 |
NL6507578A (en) | 1965-12-16 |
CH471070A (en) | 1969-04-15 |
FR5324M (en) | 1967-08-28 |
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