SE327987B - - Google Patents

Info

Publication number
SE327987B
SE327987B SE15717/66A SE1571766A SE327987B SE 327987 B SE327987 B SE 327987B SE 15717/66 A SE15717/66 A SE 15717/66A SE 1571766 A SE1571766 A SE 1571766A SE 327987 B SE327987 B SE 327987B
Authority
SE
Sweden
Application number
SE15717/66A
Inventor
B Sjoeberg
N Stjernstroem
L Carlsson
A Helgstrand
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Priority to SE15717/66A priority Critical patent/SE327987B/xx
Priority to GB03687/67A priority patent/GB1213162A/en
Priority to GB19174/67A priority patent/GB1157186A/en
Priority to DE19671795791 priority patent/DE1795791A1/de
Priority to DE1795792A priority patent/DE1795792C3/de
Priority to DE19671795789 priority patent/DE1795789A1/de
Priority to DE19671795788 priority patent/DE1795788A1/de
Priority to DE1967A0057350 priority patent/DE1670003B2/de
Priority to DE19671795790 priority patent/DE1795790A1/de
Priority to BE706471D priority patent/BE706471A/xx
Priority to NO170525A priority patent/NO124927B/no
Priority to CH1586267A priority patent/CH508625A/de
Priority to GB52041/67A priority patent/GB1171509A/en
Priority to US689751A priority patent/US3637714A/en
Priority to ES347190A priority patent/ES347190A1/es
Priority to AT1028267A priority patent/AT289113B/de
Priority to NL676715616A priority patent/NL150440B/xx
Priority to FR128477A priority patent/FR8017M/fr
Priority to FI673086A priority patent/FI49962C/fi
Priority to FR128479A priority patent/FR1544594A/fr
Priority to DK573567AA priority patent/DK125709B/da
Priority to SE15867/67A priority patent/SE364510B/xx
Priority to IE400/68A priority patent/IE32127B1/xx
Priority to DE1912352A priority patent/DE1912352C3/de
Priority to US807948A priority patent/US3622587A/en
Priority to AT268069A priority patent/AT294089B/de
Priority to FR6908585A priority patent/FR2004661A1/fr
Priority to NL6904594A priority patent/NL6904594A/xx
Publication of SE327987B publication Critical patent/SE327987B/xx
Priority to JP46021827A priority patent/JPS5023030B1/ja
Priority to US00173679A priority patent/US3781280A/en
Priority to US00173678A priority patent/US3737542A/en
Priority to US35127173 priority patent/USRE28532E/en
Priority to NL7610725A priority patent/NL7610725A/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55—Acids; Esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A61K31/455—Nicotinic acids, e.g. niacin; Derivatives thereof, e.g. esters, amides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/38—Radicals substituted by singly-bound nitrogen atoms having only hydrogen or hydrocarbon radicals attached to the substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/36—Radicals substituted by singly-bound nitrogen atoms
    • C07D213/40—Acylated substituent nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/61—Halogen atoms or nitro radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/72—Nitrogen atoms
    • C07D213/73—Unsubstituted amino or imino radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/60—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D213/78—Carbon atoms having three bonds to hetero atoms, with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/79—Acids; Esters
    • C07D213/80—Acids; Esters in position 3
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/89—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members with hetero atoms directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
SE15717/66A 1966-11-16 1966-11-16 SE327987B (de)

Priority Applications (33)

Application Number Priority Date Filing Date Title
SE15717/66A SE327987B (de) 1966-11-16 1966-11-16
GB03687/67A GB1213162A (en) 1966-11-16 1967-03-23 Serum lipid lowering pyridine derivatives and their preparation
GB19174/67A GB1157186A (en) 1966-11-16 1967-04-26 Serum Lipid Lowering Pyridine Derivatives
DE19671795791 DE1795791A1 (de) 1966-11-16 1967-11-13 Pyridinderivate, verfahren zu deren herstellung und sie enthaltende arzneimittel
DE1795792A DE1795792C3 (de) 1966-11-16 1967-11-13 Verwendung von 5-Fluornikotinsäure
DE19671795789 DE1795789A1 (de) 1966-11-16 1967-11-13 Pyridinderivate, verfahren zu deren herstellung und sie enthaltende arzneimittel
DE19671795788 DE1795788A1 (de) 1966-11-16 1967-11-13 Pyridinderivate, verfahren zu deren herstellung und sie enthaltende arzneimittel
DE1967A0057350 DE1670003B2 (de) 1966-11-16 1967-11-13 3-hydroxymethyl-5-fluorpyridin
DE19671795790 DE1795790A1 (de) 1966-11-16 1967-11-13 Pyridinderivate, verfahren zu deren herstellung und sie enthaltende arzneimittel
BE706471D BE706471A (de) 1966-11-16 1967-11-14
NO170525A NO124927B (de) 1966-11-16 1967-11-14
CH1586267A CH508625A (de) 1966-11-16 1967-11-14 Verfahren zur Herstellung von neuen serumlipoidvermindernden Pyridinderivaten
AT1028267A AT289113B (de) 1966-11-16 1967-11-15 Verfahren zur Herstellung von neuen Pyridinderivaten
US689751A US3637714A (en) 1966-11-16 1967-11-15 5 - fluoro-3-pyridinemethanol esters thereof and therapeutically acceptable salts thereof
ES347190A ES347190A1 (es) 1966-11-16 1967-11-15 Un procedimiento para la preparacion de compuestos inhibi- dores de la movilizacion de los lipidos del suero en anima- les.
GB52041/67A GB1171509A (en) 1966-11-16 1967-11-15 Pyridine Derivatives
NL676715616A NL150440B (nl) 1966-11-16 1967-11-16 Werkwijze voor het bereiden van een geneesmiddel met serumlipiden verlagende en vaatverwijdende eigenschappen dat een 3-pyridylmethanolderivaat bevat en de onder toepassing van deze werkwijze verkregen gevormde geneesmiddelen met deze eigenschappen, alsmede werkwijze voor het bereiden van dergelijke geneeskrachtige 3-pyridylmethanolderivaten.
FR128477A FR8017M (de) 1966-11-16 1967-11-16
FI673086A FI49962C (fi) 1966-11-16 1967-11-16 Menetelmä valmistaa seerumilipidipitoisuutta alentava 5-fluori-3-pyrid iini-metanoli.
FR128479A FR1544594A (fr) 1966-11-16 1967-11-16 Procédé pour l'obtention de dérivés de la pyridine et produits ainsi obtenus
DK573567AA DK125709B (da) 1966-11-16 1967-11-16 Analogifremgangsmåde til fremstilling af serumlipidsænkende 3,5-substituerede pyridinderivater eller salte deraf.
SE15867/67A SE364510B (de) 1966-11-16 1967-11-17
IE400/68A IE32127B1 (en) 1966-11-16 1968-04-08 Serum lipid lowering pyridine derivatives
DE1912352A DE1912352C3 (de) 1966-11-16 1969-03-12 Pyridin-N-oxyd-Derivale und Verfahren zu ihrer Herstellung
US807948A US3622587A (en) 1966-11-16 1969-03-17 Certain 3-pyridylmethyl-2-(p-chloro phenoxy)-2-methyl propionate-n-oxides and derivatives thereof
AT268069A AT294089B (de) 1966-11-16 1969-03-19 Verfahren zur Herstellung von neuen Pyridinderivaten und therapeutisch verträglicher Salze hievon
FR6908585A FR2004661A1 (de) 1966-11-16 1969-03-24
NL6904594A NL6904594A (de) 1966-11-16 1969-03-25
JP46021827A JPS5023030B1 (de) 1966-11-16 1971-04-09
US00173679A US3781280A (en) 1966-11-16 1971-08-20 Fluoro-pyridine derivatives and therapeutically acceptable salts thereof
US00173678A US3737542A (en) 1966-11-16 1971-08-20 Lowering excessive serum lipid concentrations and preparations containing fluoro-pyridine derivatives
US35127173 USRE28532E (en) 1966-11-16 1973-04-16 5-Fluoro-3-pyridinemethanol, esters thereof and therapeutically acceptable salts thereof
NL7610725A NL7610725A (en) 1966-11-16 1976-09-28 Fluoro nicotinate ester medicaments - with hypolipaemic and vasodilatory activity

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE15717/66A SE327987B (de) 1966-11-16 1966-11-16

Publications (1)

Publication Number Publication Date
SE327987B true SE327987B (de) 1970-09-07

Family

ID=20301108

Family Applications (1)

Application Number Title Priority Date Filing Date
SE15717/66A SE327987B (de) 1966-11-16 1966-11-16

Country Status (1)

Country Link
SE (1) SE327987B (de)

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