SE317057B - - Google Patents
Info
- Publication number
- SE317057B SE317057B SE5414/65A SE541465A SE317057B SE 317057 B SE317057 B SE 317057B SE 5414/65 A SE5414/65 A SE 5414/65A SE 541465 A SE541465 A SE 541465A SE 317057 B SE317057 B SE 317057B
- Authority
- SE
- Sweden
- Prior art keywords
- formula
- salt
- prepared
- reaction
- compound
- Prior art date
Links
- 150000003839 salts Chemical class 0.000 abstract 4
- 150000001875 compounds Chemical class 0.000 abstract 3
- ZRALSGWEFCBTJO-UHFFFAOYSA-N Guanidine Chemical compound NC(N)=N ZRALSGWEFCBTJO-UHFFFAOYSA-N 0.000 abstract 2
- 238000006243 chemical reaction Methods 0.000 abstract 2
- DWSXBFKYFXHHIL-UHFFFAOYSA-N 2-(2-methylphenyl)propanal Chemical compound O=CC(C)C1=CC=CC=C1C DWSXBFKYFXHHIL-UHFFFAOYSA-N 0.000 abstract 1
- XZMCDFZZKTWFGF-UHFFFAOYSA-N Cyanamide Chemical compound NC#N XZMCDFZZKTWFGF-UHFFFAOYSA-N 0.000 abstract 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 abstract 1
- CHJJGSNFBQVOTG-UHFFFAOYSA-N N-methyl-guanidine Natural products CNC(N)=N CHJJGSNFBQVOTG-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001299 aldehydes Chemical class 0.000 abstract 1
- 125000002947 alkylene group Chemical group 0.000 abstract 1
- HAMNKKUPIHEESI-UHFFFAOYSA-N aminoguanidine Chemical compound NNC(N)=N HAMNKKUPIHEESI-UHFFFAOYSA-N 0.000 abstract 1
- SWSQBOPZIKWTGO-UHFFFAOYSA-N dimethylaminoamidine Natural products CN(C)C(N)=N SWSQBOPZIKWTGO-UHFFFAOYSA-N 0.000 abstract 1
- 125000001301 ethoxy group Chemical group [H]C([H])([H])C([H])([H])O* 0.000 abstract 1
- 125000001495 ethyl group Chemical group [H]C([H])([H])C([H])([H])* 0.000 abstract 1
- 150000002357 guanidines Chemical class 0.000 abstract 1
- 229940083094 guanine derivative acting on arteriolar smooth muscle Drugs 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 125000000956 methoxy group Chemical group [H]C([H])([H])O* 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- 230000003647 oxidation Effects 0.000 abstract 1
- 238000007254 oxidation reaction Methods 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/21—Esters, e.g. nitroglycerine, selenocyanates
- A61K31/27—Esters, e.g. nitroglycerine, selenocyanates of carbamic or thiocarbamic acids, meprobamate, carbachol, neostigmine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C281/00—Derivatives of carbonic acid containing functional groups covered by groups C07C269/00 - C07C279/00 in which at least one nitrogen atom of these functional groups is further bound to another nitrogen atom not being part of a nitro or nitroso group
- C07C281/16—Compounds containing any of the groups, e.g. aminoguanidine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH585464A CH448057A (de) | 1964-05-05 | 1964-05-05 | Verfahren zur Herstellung von Phenylalkylaminoguanidinen |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| SE317057B true SE317057B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1969-11-10 |
Family
ID=4300408
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE6816331A SE371640B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1964-05-05 | 1965-04-26 | |
| SE5414/65A SE317057B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1964-05-05 | 1965-04-26 |
Family Applications Before (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| SE6816331A SE371640B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1964-05-05 | 1965-04-26 |
Country Status (15)
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR200F (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1965-11-15 | |||
| US3541218A (en) * | 1969-06-18 | 1970-11-17 | Lilly Co Eli | Omicron-fluorobenzylaminoguanidine for diabetes |
| JPS5051717U (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1973-09-06 | 1975-05-19 | ||
| JPS5391735U (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1976-12-27 | 1978-07-27 | ||
| JPS54121027U (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) * | 1978-02-13 | 1979-08-24 | ||
| PL124029B1 (en) * | 1979-06-01 | 1982-12-31 | Wellcome Found | Process for preparing novel derivatives of 1,2,4-triazine |
| EP0021120B1 (en) * | 1979-06-01 | 1983-04-06 | The Wellcome Foundation Limited | 3,5-diamino-1,2,4-triazine derivatives, process for preparing such compounds and pharmaceutical compositions containing them |
| FR2549049B1 (fr) * | 1983-07-13 | 1986-06-20 | Chauvin Blache Lab | Nouvelles amidines, leur procede de preparation et leur application therapeutique |
| HU190639B (en) * | 1983-12-12 | 1986-09-29 | Gyogyszerkutato Intezet Kv,Hu | Process for production of new aminoguanidin derivatives |
| EP0325936A3 (en) * | 1988-01-16 | 1990-01-17 | Ono Pharmaceutical Co., Ltd. | Aminoguanidine derivatives and inhibitory agents on maillard reaction containing them as active ingredients |
| US5891909A (en) * | 1996-03-29 | 1999-04-06 | 3-Dimensional Pharmaceuticals, Inc. | Amidinohydrazones as protease inhibitors |
| TW499412B (en) | 1996-11-26 | 2002-08-21 | Dimensional Pharm Inc | Aminoguanidines and alkoxyguanidines as protease inhibitors |
| CA2417914A1 (en) | 2000-08-04 | 2002-02-14 | 3-Dimensional Pharmaceuticals, Inc. | Cyclic oxyguanidine protease inhibitors |
-
0
- BE BE663481D patent/BE663481A/xx unknown
-
1964
- 1964-05-05 CH CH585464A patent/CH448057A/de unknown
- 1964-05-05 CH CH801766A patent/CH491873A/de not_active IP Right Cessation
- 1964-05-05 CH CH801666A patent/CH511216A/de not_active IP Right Cessation
-
1965
- 1965-04-26 AT AT806366A patent/AT255434B/de active
- 1965-04-26 AT AT806266A patent/AT255433B/de active
- 1965-04-26 SE SE6816331A patent/SE371640B/xx unknown
- 1965-04-26 SE SE5414/65A patent/SE317057B/xx unknown
- 1965-04-26 AT AT381265A patent/AT255432B/de active
- 1965-04-27 DE DE19651518222 patent/DE1518222A1/de active Pending
- 1965-04-28 IL IL23443A patent/IL23443A/xx unknown
- 1965-04-29 ES ES0312384A patent/ES312384A1/es not_active Expired
- 1965-05-03 GB GB18547/65A patent/GB1096348A/en not_active Expired
- 1965-05-03 DK DK224365AA patent/DK107288C/da active
- 1965-05-04 FI FI1086/65A patent/FI42316B/fi active
- 1965-05-04 NL NL6505684A patent/NL6505684A/xx unknown
- 1965-05-04 CS CS6249A patent/CS151461B2/cs unknown
- 1965-05-05 FR FR15815A patent/FR4399M/fr not_active Expired
- 1965-05-05 BR BR169419/65A patent/BR6569419D0/pt unknown
- 1965-05-06 JP JP40026185A patent/JPS4842627B1/ja active Pending
-
1966
- 1966-04-28 DK DK218666AA patent/DK111887B/da unknown
Also Published As
| Publication number | Publication date |
|---|---|
| FR4399M (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1966-09-05 |
| NL6505684A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1965-11-08 |
| GB1096348A (en) | 1967-12-29 |
| JPS4842627B1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-12-13 |
| SE371640B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1974-11-25 |
| AT255432B (de) | 1967-07-10 |
| CS151461B2 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1973-10-19 |
| IL23443A (en) | 1968-09-26 |
| ES312384A1 (es) | 1966-03-01 |
| BE663481A (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | |
| DE1518222A1 (de) | 1969-06-12 |
| DK111887B (da) | 1968-10-21 |
| AT255433B (de) | 1967-07-10 |
| AT255434B (de) | 1967-07-10 |
| CH448057A (de) | 1967-12-15 |
| BR6569419D0 (pt) | 1973-08-02 |
| CH491873A (de) | 1970-06-15 |
| DK107288C (da) | 1967-05-16 |
| CH511216A (de) | 1971-08-15 |
| FI42316B (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1970-03-31 |
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