SE0701694L - Nya bronkdilaterande a,b-omättade amider - Google Patents

Nya bronkdilaterande a,b-omättade amider

Info

Publication number
SE0701694L
SE0701694L SE0701694A SE0701694A SE0701694L SE 0701694 L SE0701694 L SE 0701694L SE 0701694 A SE0701694 A SE 0701694A SE 0701694 A SE0701694 A SE 0701694A SE 0701694 L SE0701694 L SE 0701694L
Authority
SE
Sweden
Prior art keywords
bronchodilating
new
unsaturated amides
compounds
bronchoconstriction
Prior art date
Application number
SE0701694A
Other languages
English (en)
Other versions
SE531698C2 (sv
Inventor
Maria Dalence
Martin Johansson
Viveca Thornqvist
Joergen Toftered
David Wensbo
Original Assignee
Respiratorius Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Respiratorius Ab filed Critical Respiratorius Ab
Priority to SE0701694A priority Critical patent/SE531698C2/sv
Priority to EP08774964A priority patent/EP2181095B1/en
Priority to US12/668,599 priority patent/US8318768B2/en
Priority to PCT/EP2008/059001 priority patent/WO2009007420A1/en
Priority to JP2010515510A priority patent/JP5443348B2/ja
Priority to ES08774964T priority patent/ES2393580T3/es
Publication of SE0701694L publication Critical patent/SE0701694L/sv
Publication of SE531698C2 publication Critical patent/SE531698C2/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/08—Bronchodilators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/06—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with the ring nitrogen atom acylated by carboxylic or carbonic acids, or with sulfur or nitrogen analogues thereof, e.g. carbamates

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
SE0701694A 2007-07-12 2007-07-12 Nya bronkdilaterande a,b-omättade amider SE531698C2 (sv)

Priority Applications (6)

Application Number Priority Date Filing Date Title
SE0701694A SE531698C2 (sv) 2007-07-12 2007-07-12 Nya bronkdilaterande a,b-omättade amider
EP08774964A EP2181095B1 (en) 2007-07-12 2008-07-10 Novel bronchodilating alpha, beta-unsaturated isoquinoline amides
US12/668,599 US8318768B2 (en) 2007-07-12 2008-07-10 Bronchodilating alpha, beta-unsaturated isoquinoline amides
PCT/EP2008/059001 WO2009007420A1 (en) 2007-07-12 2008-07-10 Novel bronchodilating alpha, beta-unsaturated isoquinoline amides
JP2010515510A JP5443348B2 (ja) 2007-07-12 2008-07-10 新規な気管支拡張性α，β−不飽和イソキノリンアミド
ES08774964T ES2393580T3 (es) 2007-07-12 2008-07-10 Isoquinolin-amidas alfa,beta-insaturadas broncodilatadoras novedosas

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE0701694A SE531698C2 (sv) 2007-07-12 2007-07-12 Nya bronkdilaterande a,b-omättade amider

Publications (2)

Publication Number Publication Date
SE0701694L true SE0701694L (sv) 2009-01-13
SE531698C2 SE531698C2 (sv) 2009-07-07

Family

ID=39884108

Family Applications (1)

Application Number Title Priority Date Filing Date
SE0701694A SE531698C2 (sv) 2007-07-12 2007-07-12 Nya bronkdilaterande a,b-omättade amider

Country Status (6)

Country Link
US (1) US8318768B2 (sv)
EP (1) EP2181095B1 (sv)
JP (1) JP5443348B2 (sv)
ES (1) ES2393580T3 (sv)
SE (1) SE531698C2 (sv)
WO (1) WO2009007420A1 (sv)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
UY32521A (es) * 2009-04-03 2010-10-29 Astrazeneca Ab Combinación para emplear en el tratamiento de enfermedades respiratorias
CN102614177B (zh) * 2012-03-06 2014-08-06 北京伟峰益民科技有限公司 卢帕他定在制备治疗慢性阻塞性肺病药物组合物中的应用
KR20210032315A (ko) * 2018-07-06 2021-03-24 레스피라토리우스 아브 신규한 기관지 확장형 헤테로 결합된 아미드

Family Cites Families (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU652996B2 (en) * 1991-01-11 1994-09-15 Laboratoires Glaxo S.A. Acridine derivatives
US5124337A (en) 1991-05-20 1992-06-23 Schering Corporation N-acyl-tetrahydroisoquinolines as inhibitors of acyl-coenzyme a:cholesterol acyl transferase
JPH05239024A (ja) 1992-02-28 1993-09-17 Takeda Chem Ind Ltd 縮合複素環カルボン酸誘導体、その製造法、中間体および剤
US5767129A (en) * 1995-08-24 1998-06-16 Warner-Lambert Company Substituted quinolines and isoquinolines as calcium channel blockers, their preparation and the use thereof
SE9504618D0 (sv) 1995-12-22 1995-12-22 Astra Ab New Compounds
IL129122A0 (en) 1996-10-04 2000-02-17 Novo Nordisk As N-substituted azaheterocyclic compounds
GB9717576D0 (en) 1997-08-19 1997-10-22 Xenova Ltd Pharmaceutical compounds
US5665880A (en) 1996-10-31 1997-09-09 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseretholes
US5932590A (en) 1996-12-05 1999-08-03 Merck & Co., Inc. Inhibitors of farnesyl-protein transferase
US5677457A (en) 1996-12-19 1997-10-14 Hoechst Marion Roussel, Inc. Method of preparation of physostigmine carbamate derivatives from eseroline ethers
AU779266B2 (en) * 2000-05-11 2005-01-13 Banyu Pharmaceutical Co., Ltd. N-acyltetrahydroisoquinoline derivatives
AR028685A1 (es) 2000-06-14 2003-05-21 Lundbeck & Co As H Derivados de indol
KR20030011365A (ko) 2000-06-29 2003-02-07 하. 룬트벡 아크티에 셀스카브 Ｃｎｓ 장애 치료에 유용한 인돌 유도체
DE10153348A1 (de) 2001-10-29 2003-05-08 Gruenenthal Gmbh Substituierte Benzo(b)azepin-2-on-Verbindungen
SE0103644D0 (sv) 2001-11-01 2001-11-01 Astrazeneca Ab Therapeutic isoquinoline compounds
US20040266732A1 (en) 2002-09-20 2004-12-30 Jorge Galvez Therapeutic agents, methods, and treatments
DE10304870A1 (de) 2003-02-06 2004-08-19 Abbott Gmbh & Co. Kg Triazolverbindungen und ihre therapeutische Verwendung
EP1660454A1 (en) 2003-07-07 2006-05-31 Vernalis (R&D) Limited Azacyclic compounds as inhibitors of sensory neurone specific channels
PL1680137T3 (pl) 2003-10-14 2013-04-30 F Hoffmann La Roche Ltd Makrocykliczny kwas karboksylowy i związek acylosulfonamidowy jako inhibitor replikacji HCV
CN100528162C (zh) 2003-12-19 2009-08-19 先灵公司 药物组合物
US20050165004A1 (en) * 2004-01-22 2005-07-28 Staffan Skogvall Bronchorelaxing compounds
WO2005092841A1 (en) 2004-03-23 2005-10-06 Pfizer Limited Compounds having beta-agonist activity
WO2005095403A2 (en) 2004-03-30 2005-10-13 Intermune, Inc. Macrocyclic compounds as inhibitors of viral replication
EP1598341A1 (en) 2004-05-21 2005-11-23 Santhera Pharmaceuticals (Deutschland) Aktiengesellschaft DPP-IV inhibitors
WO2006012504A2 (en) 2004-07-23 2006-02-02 Daiamed, Inc. Compounds and methods for treatment of thrombosis
WO2007011290A1 (en) * 2005-07-18 2007-01-25 Respiratorius Ab Bronchorelaxing agents based on indol- and isoquinoline derivatives
DE102005062987A1 (de) * 2005-12-28 2007-07-05 Grünenthal GmbH Substituierte Propiolsäureamide und ihre Verwendung zur Herstellung von Arzneimitteln
WO2009007419A1 (en) 2007-07-12 2009-01-15 Respiratorius Ab Novel bronchodilating isoquinoline carbamates
WO2009007418A1 (en) 2007-07-12 2009-01-15 Respiratorius Ab Novel bronchodilating isoquinoline amides

Also Published As

Publication number Publication date
EP2181095A1 (en) 2010-05-05
JP5443348B2 (ja) 2014-03-19
SE531698C2 (sv) 2009-07-07
ES2393580T3 (es) 2012-12-26
US20100256101A1 (en) 2010-10-07
EP2181095B1 (en) 2012-08-22
WO2009007420A1 (en) 2009-01-15
US8318768B2 (en) 2012-11-27
JP2010533145A (ja) 2010-10-21

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