RU99121636A - METHOD FOR PRODUCING L-AMINO ACIDS BY FERMENTATION - Google Patents
METHOD FOR PRODUCING L-AMINO ACIDS BY FERMENTATIONInfo
- Publication number
- RU99121636A RU99121636A RU99121636/13A RU99121636A RU99121636A RU 99121636 A RU99121636 A RU 99121636A RU 99121636/13 A RU99121636/13 A RU 99121636/13A RU 99121636 A RU99121636 A RU 99121636A RU 99121636 A RU99121636 A RU 99121636A
- Authority
- RU
- Russia
- Prior art keywords
- amino acids
- bacterium
- producing
- gene encoding
- nutrient medium
- Prior art date
Links
- 150000008575 L-amino acids Chemical class 0.000 title claims 7
- 238000004519 manufacturing process Methods 0.000 title claims 3
- 230000004151 fermentation Effects 0.000 title 1
- 238000000855 fermentation Methods 0.000 title 1
- 241000894006 Bacteria Species 0.000 claims 8
- ODKSFYDXXFIFQN-BYPYZUCNSA-N L-arginine Chemical compound OC(=O)[C@@H](N)CCCN=C(N)N ODKSFYDXXFIFQN-BYPYZUCNSA-N 0.000 claims 4
- WHUUTDBJXJRKMK-VKHMYHEASA-N L-glutamic acid Chemical compound OC(=O)[C@@H](N)CCC(O)=O WHUUTDBJXJRKMK-VKHMYHEASA-N 0.000 claims 4
- UKAUYVFTDYCKQA-VKHMYHEASA-N L-homoserine zwitterion Chemical compound OC(=O)[C@@H](N)CCO UKAUYVFTDYCKQA-VKHMYHEASA-N 0.000 claims 4
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 claims 4
- AYFVYJQAPQTCCC-GBXIJSLDSA-N L-threonine Chemical compound C[C@@H](O)[C@H](N)C(O)=O AYFVYJQAPQTCCC-GBXIJSLDSA-N 0.000 claims 4
- 108010053763 EC 6.4.1.1 Proteins 0.000 claims 3
- 102100007000 PC Human genes 0.000 claims 3
- 235000015097 nutrients Nutrition 0.000 claims 3
- 229960002989 Glutamic Acid Drugs 0.000 claims 2
- 229960000310 ISOLEUCINE Drugs 0.000 claims 2
- 235000014852 L-arginine Nutrition 0.000 claims 2
- AGPKZVBTJJNPAG-WHFBIAKZSA-N L-isoleucine Chemical compound CC[C@H](C)[C@H](N)C(O)=O AGPKZVBTJJNPAG-WHFBIAKZSA-N 0.000 claims 2
- ONIBWKKTOPOVIA-BYPYZUCNSA-N L-proline Chemical compound OC(=O)[C@@H]1CCCN1 ONIBWKKTOPOVIA-BYPYZUCNSA-N 0.000 claims 2
- 229960004452 Methionine Drugs 0.000 claims 2
- 229960002429 Proline Drugs 0.000 claims 2
- 239000004473 Threonine Substances 0.000 claims 2
- 229960002898 threonine Drugs 0.000 claims 2
- 241000193830 Bacillus <bacterium> Species 0.000 claims 1
- 241000588722 Escherichia Species 0.000 claims 1
- 238000009825 accumulation Methods 0.000 claims 1
- 238000000605 extraction Methods 0.000 claims 1
Claims (6)
Priority Applications (7)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU99121636/13A RU2207376C2 (en) | 1999-10-14 | 1999-10-14 | Method for preparing l-amino acid by fermentation method, strain of bacterium escherichia coli as producer of l-amino acid (variants) |
JP2000302598A JP2001136991A (en) | 1999-10-14 | 2000-10-02 | Method for producing l-amino acid by fermentation method |
EP00121763A EP1092776B1 (en) | 1999-10-14 | 2000-10-05 | Method for producing L-amino acids by fermentation of an Escherichia strain which is transformed with a pyruvate carboxylase-encoding gene from Bacilus subtilis |
DE60011974T DE60011974T2 (en) | 1999-10-14 | 2000-10-05 | Process for the preparation of L-amino acids by fermentation of an Escherichia strain transformed with a pyruvate carboxylase gene from Bacillus subtilis |
SK1511-2000A SK285997B6 (en) | 1999-10-14 | 2000-10-11 | Bacterium belonging to the genus Escherichia being transformed by the gene encoding pyruvate carboxylase and which produces L-amino acid, and fermentative method for producing L-amino acid |
BR0004832-1A BR0004832A (en) | 1999-10-14 | 2000-10-13 | Bacteria belonging to the genus escherichia, and, process to produce l-amino acid |
CNB001348914A CN1247783C (en) | 1999-10-14 | 2000-10-14 | Fermentation method of producing L-amino acid |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
RU99121636/13A RU2207376C2 (en) | 1999-10-14 | 1999-10-14 | Method for preparing l-amino acid by fermentation method, strain of bacterium escherichia coli as producer of l-amino acid (variants) |
Publications (2)
Publication Number | Publication Date |
---|---|
RU99121636A true RU99121636A (en) | 2002-05-27 |
RU2207376C2 RU2207376C2 (en) | 2003-06-27 |
Family
ID=20225848
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU99121636/13A RU2207376C2 (en) | 1999-10-14 | 1999-10-14 | Method for preparing l-amino acid by fermentation method, strain of bacterium escherichia coli as producer of l-amino acid (variants) |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP1092776B1 (en) |
JP (1) | JP2001136991A (en) |
CN (1) | CN1247783C (en) |
BR (1) | BR0004832A (en) |
DE (1) | DE60011974T2 (en) |
RU (1) | RU2207376C2 (en) |
SK (1) | SK285997B6 (en) |
Families Citing this family (39)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
RU2175351C2 (en) * | 1998-12-30 | 2001-10-27 | Закрытое акционерное общество "Научно-исследовательский институт "Аджиномото-Генетика" (ЗАО "АГРИ") | Escherichia coli dna fragment determining enhanced production of l-amino acids (variants) and method of l-amino acid producing |
RU2207371C2 (en) | 2000-09-26 | 2003-06-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" | Method for preparing l-amino acids of l-glutamic acid family, strain of bacterium escherichia coli as producer of l-amino acid (variants) |
JP2006230202A (en) * | 2003-06-23 | 2006-09-07 | Ajinomoto Co Inc | Method for producing l-glutamic acid |
EP1907559A1 (en) * | 2005-07-18 | 2008-04-09 | Basf Se | Methionine producing recombinant microorganisms |
PE20071235A1 (en) * | 2006-01-27 | 2007-12-02 | Ajinomoto Kk | METHOD FOR PRODUCING L-AMINO ACIDS |
WO2007086618A1 (en) | 2006-01-30 | 2007-08-02 | Ajinomoto Co., Inc. | L-amino acid producing bacterium and method of producing l-amino acid |
JP2009118740A (en) | 2006-03-03 | 2009-06-04 | Ajinomoto Co Inc | Method for producing l-amino acid |
CN1986777B (en) * | 2006-07-11 | 2010-09-08 | 湖北大学 | Vital catalyzing engineering bacterium and its L-type hydrophobic amino acid producing process with alpha-keto acid |
JP2010017082A (en) | 2006-10-10 | 2010-01-28 | Ajinomoto Co Inc | Method for producing l-amino acid |
JP2010041920A (en) | 2006-12-19 | 2010-02-25 | Ajinomoto Co Inc | Method for producing l-amino acid |
JP2010088301A (en) | 2007-02-01 | 2010-04-22 | Ajinomoto Co Inc | Method for production of l-amino acid |
JP2010110216A (en) | 2007-02-20 | 2010-05-20 | Ajinomoto Co Inc | Method for producing l-amino acid or nucleic acid |
RU2395579C2 (en) | 2007-12-21 | 2010-07-27 | Закрытое акционерное общество "Научно-исследовательский институт Аджиномото-Генетика" (ЗАО АГРИ) | METHOD OF PRODUCING L-AMINO ACIDS USING Escherichia GENUS BACTERIA |
JP2010263790A (en) | 2007-09-04 | 2010-11-25 | Ajinomoto Co Inc | Amino acid-producing microorganism and method for producing amino acid |
EP2192170B1 (en) * | 2007-09-04 | 2017-02-15 | Ajinomoto Co., Inc. | Amino acid-producing microorganism and method of producing amino acid |
JP2011067095A (en) | 2008-01-10 | 2011-04-07 | Ajinomoto Co Inc | Method for producing target substance by fermentation process |
CN102348806A (en) | 2008-01-23 | 2012-02-08 | 味之素株式会社 | Method of producing l-amino acid |
WO2010027045A1 (en) | 2008-09-08 | 2010-03-11 | 味の素株式会社 | Microorganism capable of producing l-amino acid, and method for producing l-amino acid |
JP2012029565A (en) | 2008-11-27 | 2012-02-16 | Ajinomoto Co Inc | Method for producing l-amino acid |
EP2460883A4 (en) | 2009-07-29 | 2013-01-16 | Ajinomoto Kk | Method for producing l-amino acid |
JP2012223091A (en) | 2009-08-25 | 2012-11-15 | Ajinomoto Co Inc | Method for producing l-amino acid |
JP2012223092A (en) | 2009-08-28 | 2012-11-15 | Ajinomoto Co Inc | Method for producing l-amino acid |
JP2013013329A (en) | 2009-11-06 | 2013-01-24 | Ajinomoto Co Inc | Method for producing l-amino acid |
EP2868745B1 (en) | 2013-05-13 | 2017-06-21 | Ajinomoto Co., Inc. | Method for manufacturing an L-amino acid |
JP2016165225A (en) | 2013-07-09 | 2016-09-15 | 味の素株式会社 | Method for producing useful substance |
JP2016192903A (en) | 2013-09-17 | 2016-11-17 | 味の素株式会社 | Method for manufacturing l-amino acid from biomass derived from seaweed |
JP5958653B2 (en) | 2013-10-02 | 2016-08-02 | 味の素株式会社 | Ammonia control device and ammonia control method |
WO2015060314A1 (en) | 2013-10-21 | 2015-04-30 | 味の素株式会社 | Method for producing l-amino acid |
JP6519476B2 (en) | 2013-10-23 | 2019-05-29 | 味の素株式会社 | Production method of target substance |
JP2015156844A (en) * | 2014-02-25 | 2015-09-03 | 花王株式会社 | Bacillus subtilis variant and method for producing of dipicolinic acid using the same |
CN105505969A (en) * | 2014-09-26 | 2016-04-20 | 中国科学院天津工业生物技术研究所 | Method for improving conversion rate of L-threonine and application of method |
JP6623690B2 (en) | 2015-10-30 | 2019-12-25 | 味の素株式会社 | Method for producing glutamic acid-based L-amino acid |
CN106148261B (en) * | 2016-07-01 | 2019-09-03 | 江南大学 | A kind of recombined bacillus subtilis and its construction method improving acetylglucosamine yield |
JP7066977B2 (en) | 2017-04-03 | 2022-05-16 | 味の素株式会社 | Manufacturing method of L-amino acid |
KR101947959B1 (en) * | 2018-05-28 | 2019-02-13 | 씨제이제일제당 (주) | A modified homoserine dehydrogenase and a method for producing homoserine or L- amino acid derived from homoserine using the same |
EP3861109A1 (en) | 2018-10-05 | 2021-08-11 | Ajinomoto Co., Inc. | Method for producing target substance by bacterial fermentation |
RU2714763C1 (en) * | 2018-11-08 | 2020-02-19 | Генетик Диагностикс Энд Терапи 21 Лтд | Gene-therapeutic dna vector for targeted gene therapy, method for production thereof (embodiments), strain for production thereof, method for production thereof |
WO2022092018A1 (en) | 2020-10-28 | 2022-05-05 | 味の素株式会社 | Method of producing l-amino acid |
US20240117393A1 (en) | 2022-09-30 | 2024-04-11 | Ajinomoto Co., Inc. | Method for producing l-amino acid |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SU875663A1 (en) * | 1978-06-30 | 1982-09-15 | Всесоюзный научно-исследовательский институт генетики и селекции промышленных микроорганизмов | Strains e. coli vniigenetika voltage 334 ru no.6 and vniigenetika voltage 334 no.7 producersof l-treonite and method for preparing them |
WO1997008294A1 (en) * | 1995-08-23 | 1997-03-06 | Ajinomoto Co., Inc. | Process for producing l-glutamic acid by fermentation method |
EP1015621B1 (en) * | 1997-10-04 | 2005-03-09 | Degussa AG | Method for microbial production of amino acids of the aspartate and/or glutamate family and agents which can be used in said method |
ATE458040T1 (en) * | 1998-04-13 | 2010-03-15 | Univ Georgia | PYRUVATE CARBOXYLASE OVEREXPRESSION TO INCREASE PRODUCTION OF OXALACETATE DERIVED COMPOUNDS IN MICROBIAL CELLS |
-
1999
- 1999-10-14 RU RU99121636/13A patent/RU2207376C2/en active
-
2000
- 2000-10-02 JP JP2000302598A patent/JP2001136991A/en active Pending
- 2000-10-05 DE DE60011974T patent/DE60011974T2/en not_active Expired - Lifetime
- 2000-10-05 EP EP00121763A patent/EP1092776B1/en not_active Expired - Lifetime
- 2000-10-11 SK SK1511-2000A patent/SK285997B6/en not_active IP Right Cessation
- 2000-10-13 BR BR0004832-1A patent/BR0004832A/en not_active Application Discontinuation
- 2000-10-14 CN CNB001348914A patent/CN1247783C/en not_active Expired - Fee Related
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