RU94016976A - METHOD OF OBTAINING INDIA GENERATOR - 113M - Google Patents

METHOD OF OBTAINING INDIA GENERATOR - 113M

Info

Publication number
RU94016976A
RU94016976A RU94016976/25A RU94016976A RU94016976A RU 94016976 A RU94016976 A RU 94016976A RU 94016976/25 A RU94016976/25 A RU 94016976/25A RU 94016976 A RU94016976 A RU 94016976A RU 94016976 A RU94016976 A RU 94016976A
Authority
RU
Russia
Prior art keywords
sorption
tin
solution
generator
indium
Prior art date
Application number
RU94016976/25A
Other languages
Russian (ru)
Other versions
RU2073928C1 (en
Inventor
В.В. Басманов
О.В. Старков
М.Д. Козлова
Р.В. Юдинцев
Original Assignee
Физико-энергетический институт
Filing date
Publication date
Application filed by Физико-энергетический институт filed Critical Физико-энергетический институт
Priority to RU94016976A priority Critical patent/RU2073928C1/en
Priority claimed from RU94016976A external-priority patent/RU2073928C1/en
Publication of RU94016976A publication Critical patent/RU94016976A/en
Application granted granted Critical
Publication of RU2073928C1 publication Critical patent/RU2073928C1/en

Links

Claims (1)

Использование: изобретение относится к производству радиоактивного препарата индия - 113 м, применяемого в качестве визуализирующего агента в составе радиофармацевтических препаратов для целей медицинской диагностики. Сущность изобретения: генератор индия - 113м получают путем растворения облученного олова в концентрированной соляной кислоте в присутствии окислителя, разбавлении раствора водой, последовательного пропускания полученного раствора через обработанный гидрофильным веществом стерилизующий микробиологический фильтр и предварительно простерилизованную сорбционную колонку, промывки и элюировании индия - 113м разбавленной соляной кислотой. Концентрацию облученного олова в растворе для сорбции выбирают в интервале от 0,02 до 0,2 мг/мл, а расход устанавливают в пределах от 1 до 5 мл/мин. Положительный эффект заключается в устранении трудоемкости и многостадийности прецизионных ручных операций с радиоактивными веществами, повышении безопасности работ, сокращении длительности процесса до 60 - 180 мин при увеличении степени сорбции олова до 99,99%. 1 н. и 2 з. п. ф-лы.Usage: the invention relates to the production of a radioactive drug indium - 113 m, used as an imaging agent in the composition of radiopharmaceutical preparations for the purposes of medical diagnostics. The essence of the invention: Indium-113m generator is obtained by dissolving irradiated tin in concentrated hydrochloric acid in the presence of an oxidizing agent, diluting the solution with water, sequentially passing the resulting solution through a sterilizing microbiological filter treated with a hydrophilic substance and a pre-sterilized sorption column . The concentration of the irradiated tin in the solution for sorption is chosen in the range from 0.02 to 0.2 mg / ml, and the flow rate is set in the range from 1 to 5 ml / min. The positive effect is to eliminate the laboriousness and multi-stage precision of manual operations with radioactive substances, increase the safety of work, reduce the duration of the process to 60–180 minutes while increasing the degree of sorption of tin to 99.99%. 1 n. and 2 h. apt.
RU94016976A 1994-05-11 1994-05-11 Method of preparing indium-113m generator RU2073928C1 (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
RU94016976A RU2073928C1 (en) 1994-05-11 1994-05-11 Method of preparing indium-113m generator

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
RU94016976A RU2073928C1 (en) 1994-05-11 1994-05-11 Method of preparing indium-113m generator

Publications (2)

Publication Number Publication Date
RU94016976A true RU94016976A (en) 1996-01-27
RU2073928C1 RU2073928C1 (en) 1997-02-20

Family

ID=20155667

Family Applications (1)

Application Number Title Priority Date Filing Date
RU94016976A RU2073928C1 (en) 1994-05-11 1994-05-11 Method of preparing indium-113m generator

Country Status (1)

Country Link
RU (1) RU2073928C1 (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107293346A (en) * 2017-06-08 2017-10-24 天津汇康药业有限公司 A kind of Sn 113/In 113m generators and preparation method

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