RU93058510A - Способ получения 3,4-дигидрокси-5-нитробензальдегида - Google Patents
Способ получения 3,4-дигидрокси-5-нитробензальдегидаInfo
- Publication number
- RU93058510A RU93058510A RU93058510/04A RU93058510A RU93058510A RU 93058510 A RU93058510 A RU 93058510A RU 93058510/04 A RU93058510/04 A RU 93058510/04A RU 93058510 A RU93058510 A RU 93058510A RU 93058510 A RU93058510 A RU 93058510A
- Authority
- RU
- Russia
- Prior art keywords
- nitrobenzaldehyde
- dihydroxy
- producing
- reacting
- reaction
- Prior art date
Links
- BBFJODMCHICIAA-UHFFFAOYSA-N 3,4-Dihydroxy-5-nitrobenzaldehyde Chemical compound OC1=CC(C=O)=CC([N+]([O-])=O)=C1O BBFJODMCHICIAA-UHFFFAOYSA-N 0.000 title claims 2
- 238000004519 manufacturing process Methods 0.000 title claims 2
- WMFOQBRAJBCJND-UHFFFAOYSA-M lithium hydroxide Chemical compound [Li+].[OH-] WMFOQBRAJBCJND-UHFFFAOYSA-M 0.000 claims 3
- ZEHYRTJBFMZHCY-UHFFFAOYSA-N 5-nitrovanillin Chemical compound COC1=CC(C=O)=CC([N+]([O-])=O)=C1O ZEHYRTJBFMZHCY-UHFFFAOYSA-N 0.000 claims 1
- 229910052783 alkali metal Inorganic materials 0.000 claims 1
- 150000001340 alkali metals Chemical class 0.000 claims 1
- -1 aromatic mercapto compound Chemical class 0.000 claims 1
- 239000002585 base Substances 0.000 claims 1
- 239000003795 chemical substances by application Substances 0.000 claims 1
- 230000000269 nucleophilic Effects 0.000 claims 1
- 239000002798 polar solvent Substances 0.000 claims 1
Claims (1)
- Способ получения 3,4-дигидрокси-5-нитробензальдегида путем взаимодействия 4-гидрокси-3-метокси-5-нитробензальдегида с сильным нуклеофильным агентом, который можно получить посредством взаимодействия ароматического меркаптосоединения с сильным органическим или неорганическим основанием щелочного металла, таким как гидроксид лития. Реакцию проводят при повышенных температурах, используя апротонный полярный растворитель. Предпочтительно проводить реакцию в инертной атмосфере.
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB919113431A GB9113431D0 (en) | 1991-06-20 | 1991-06-20 | Method for the preparation of 3,4-dihydroxy-5-nitrobenzaldehyde |
GB9113431.2 | 1991-06-20 | ||
PCT/FI1992/000192 WO1993000323A1 (en) | 1991-06-20 | 1992-06-18 | Method for the preparation of 3,4-dihydroxy-5-nitrobenzaldehyde |
Publications (2)
Publication Number | Publication Date |
---|---|
RU93058510A true RU93058510A (ru) | 1996-12-27 |
RU2098405C1 RU2098405C1 (ru) | 1997-12-10 |
Family
ID=10697088
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU9393058510A RU2098405C1 (ru) | 1991-06-20 | 1992-06-18 | Способ получения 3,4-дигидрокси-5-нитробензальдегида |
Country Status (23)
Country | Link |
---|---|
US (1) | US5382699A (ru) |
EP (1) | EP0589948B1 (ru) |
JP (1) | JP3048639B2 (ru) |
KR (1) | KR100241132B1 (ru) |
AT (1) | ATE142192T1 (ru) |
AU (1) | AU650149B2 (ru) |
BG (1) | BG62163B1 (ru) |
CA (1) | CA2110583C (ru) |
CZ (1) | CZ281933B6 (ru) |
DE (1) | DE69213452T2 (ru) |
DK (1) | DK0589948T3 (ru) |
EE (1) | EE03068B1 (ru) |
ES (1) | ES2091472T3 (ru) |
FI (1) | FI104715B (ru) |
GB (1) | GB9113431D0 (ru) |
GR (1) | GR3021052T3 (ru) |
HU (1) | HU211121B (ru) |
NO (1) | NO178298C (ru) |
PL (1) | PL169522B1 (ru) |
RO (1) | RO115157B1 (ru) |
RU (1) | RU2098405C1 (ru) |
SK (1) | SK281800B6 (ru) |
WO (1) | WO1993000323A1 (ru) |
Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9419274D0 (en) * | 1994-09-23 | 1994-11-09 | Orion Yhtymae Oy | New method for the preparation of 3,4-dihydroxy-5-nitrobenzaldehyde |
US7339060B2 (en) | 2005-03-23 | 2008-03-04 | Resolution Chemicals, Ltd. | Preparation of cabergoline |
US20070197576A1 (en) * | 2006-02-08 | 2007-08-23 | Resolution Chemicals Limited | Production of Cabergoline and Novel Polymorphic Form Thereof |
EP2251323B1 (en) | 2009-05-14 | 2014-04-23 | F.I.S.- Fabbrica Italiana Sintetici S.p.A. | Method for the purification of entacapone |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
NL279980A (ru) * | 1961-06-21 | |||
US4009210A (en) * | 1975-05-07 | 1977-02-22 | Gulf Oil Corporation | Process for manufacturing 3,5-ditert.butyl-4-hydroxybenzaldehyde by formylation of 2,6-ditert.butylphenol |
DK175069B1 (da) * | 1986-03-11 | 2004-05-24 | Hoffmann La Roche | Pyrocatecholderivater |
YU213587A (en) * | 1986-11-28 | 1989-06-30 | Orion Yhtymae Oy | Process for obtaining new pharmacologic active cateholic derivatives |
FI864875A0 (fi) * | 1986-11-28 | 1986-11-28 | Orion Yhtymae Oy | Nya farmakologiskt aktiva foereningar, dessa innehaollande kompositioner samt foerfarande och mellanprodukter foer anvaendning vid framstaellning av dessa. |
GB2238047B (en) * | 1989-11-03 | 1993-02-10 | Orion Yhtymae Oy | Stable polymorphic form of (e)-n,n-diethyl-2-cyano-3-(3,4-dihydroxy-5-nitrophenyl)acrylamide and the process for its preparation |
-
1991
- 1991-06-20 GB GB919113431A patent/GB9113431D0/en active Pending
-
1992
- 1992-06-18 JP JP4510758A patent/JP3048639B2/ja not_active Expired - Fee Related
- 1992-06-18 WO PCT/FI1992/000192 patent/WO1993000323A1/en active IP Right Grant
- 1992-06-18 RU RU9393058510A patent/RU2098405C1/ru not_active IP Right Cessation
- 1992-06-18 DE DE69213452T patent/DE69213452T2/de not_active Expired - Fee Related
- 1992-06-18 DK DK92911745.5T patent/DK0589948T3/da active
- 1992-06-18 KR KR1019930703777A patent/KR100241132B1/ko not_active IP Right Cessation
- 1992-06-18 CZ CS932804A patent/CZ281933B6/cs not_active IP Right Cessation
- 1992-06-18 SK SK1446-93A patent/SK281800B6/sk unknown
- 1992-06-18 ES ES92911745T patent/ES2091472T3/es not_active Expired - Lifetime
- 1992-06-18 AU AU18980/92A patent/AU650149B2/en not_active Ceased
- 1992-06-18 CA CA002110583A patent/CA2110583C/en not_active Expired - Fee Related
- 1992-06-18 AT AT92911745T patent/ATE142192T1/de not_active IP Right Cessation
- 1992-06-18 RO RO93-01717A patent/RO115157B1/ro unknown
- 1992-06-18 HU HU9303667A patent/HU211121B/hu not_active IP Right Cessation
- 1992-06-18 EP EP92911745A patent/EP0589948B1/en not_active Expired - Lifetime
- 1992-06-18 PL PL92301827A patent/PL169522B1/pl not_active IP Right Cessation
- 1992-06-18 US US08/162,198 patent/US5382699A/en not_active Expired - Lifetime
-
1993
- 1993-12-10 BG BG98285A patent/BG62163B1/bg unknown
- 1993-12-16 FI FI935657A patent/FI104715B/fi active
- 1993-12-16 NO NO934664A patent/NO178298C/no unknown
-
1994
- 1994-11-01 EE EE9400168A patent/EE03068B1/xx not_active IP Right Cessation
-
1996
- 1996-09-17 GR GR960402420T patent/GR3021052T3/el unknown
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CA2135138A1 (en) | Method for producing formic acid or its derivatives | |
CA2200734A1 (en) | The preparation of fluorinated organic compounds | |
CA2083001A1 (en) | Lithium secondary battery using a non-aqueous solvent | |
FR2524474B1 (ru) | ||
EP1498978A4 (en) | WATER-FREE ELECTROLYTE SOLUTION AND LITHIUM SECONDARY BATTERY THEREWITH | |
JPS54157503A (en) | Manufacture of organic fluoro compound | |
EP0266182A3 (en) | Gamma-lactonecarboxylic acid derivatives and their production | |
RU93058510A (ru) | Способ получения 3,4-дигидрокси-5-нитробензальдегида | |
AU5377190A (en) | Improvements in or relating to organic compounds | |
ZA822582B (en) | Chemical process | |
JPS6472901A (en) | Production of lithium fluoride complex salt | |
CA2110583A1 (en) | Method for the preparation of 3,4-dihydroxy-5-nitrobenzaldehyde | |
MX169728B (es) | Procedimiento para la obtencion de poliglicoleteres cerrados en los grupos terminales | |
DE2967550D1 (en) | Method of making an organic metal salt or complex | |
WO2004037766A3 (en) | Process for the preparation of 2,6-dihalo-para-trifluoromethylaniline | |
EP1634882A4 (en) | INOSIN DERIVATIVE AND METHOD FOR THE PRODUCTION THEREOF | |
DE3360106D1 (en) | Process for the production of oil-soluble metal salts | |
EP1132391A4 (en) | PRODUCTION METHOD FOR 3-SULFONYLOXY-3-CEPHEM COMPOUNDS | |
JPS5581818A (en) | Method of fluorination | |
AU556591B2 (en) | Process for production of methyl 2-tetradecylglycidate | |
UA896A1 (ru) | Неводный малополярный электролит | |
JPS5392733A (en) | Preparation of alkylbenzenesulfonic acid cobalt salt solution | |
JPS52106810A (en) | Preparation of alpha-thioketones | |
JPS5767586A (en) | Preparation of 5-methyl-1,2,4-triazolo(3,4-b)benzothiazole | |
JPS52105136A (en) | Preparation of aminophenolalkylethers |