RU93056850A - ANTIRETROVIRAL HYDRAZINE DERIVATIVES - Google Patents
ANTIRETROVIRAL HYDRAZINE DERIVATIVESInfo
- Publication number
- RU93056850A RU93056850A RU93056850/04A RU93056850A RU93056850A RU 93056850 A RU93056850 A RU 93056850A RU 93056850/04 A RU93056850/04 A RU 93056850/04A RU 93056850 A RU93056850 A RU 93056850A RU 93056850 A RU93056850 A RU 93056850A
- Authority
- RU
- Russia
- Prior art keywords
- unsubstituted
- antiretroviral
- substituted alkyl
- hydrogen
- hydrazine derivatives
- Prior art date
Links
- 230000000798 anti-retroviral Effects 0.000 title claims 2
- 150000002429 hydrazines Chemical class 0.000 title 1
- 229910052739 hydrogen Inorganic materials 0.000 claims 5
- 239000001257 hydrogen Substances 0.000 claims 5
- 125000000547 substituted alkyl group Chemical group 0.000 claims 5
- 150000001875 compounds Chemical class 0.000 claims 3
- UFHFLCQGNIYNRP-UHFFFAOYSA-N hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 claims 3
- 125000003107 substituted aryl group Chemical group 0.000 claims 3
- 150000002431 hydrogen Chemical class 0.000 claims 2
- 125000005346 substituted cycloalkyl group Chemical group 0.000 claims 2
- 125000002252 acyl group Chemical group 0.000 claims 1
- 125000004423 acyloxy group Chemical group 0.000 claims 1
- 125000000623 heterocyclic group Chemical group 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 125000000020 sulfo group Chemical group O=S(=O)([*])O[H] 0.000 claims 1
- 125000000472 sulfonyl group Chemical group *S(*)(=O)=O 0.000 claims 1
Claims (1)
где R1 и R9 - независимо друг от друга водород, ацил, незамещенный либо замещенный алкил, сульфо или сульфонил, замещенный незамещенным либо замещенным алкилом, арилом или гетероциклилом, при условии, что максимум один из радикалов R1 и R9 - водород; R2 и R8 - соответственно независимо друг от друга водород или незамещенный либо замещенный алкил; R3 и R4 - независимо друг от друга водород, незамещенный либо замещенный алкил, незамещенный либо замещенный циклоалкил или арил; R5 - ацилокси; R6 - водород; R7 - незамещенный либо замещенный алкил, незамещенный либо замещенный циклоалкил или арил, а также соли соединений при наличии солеобразующих групп. Эти соединения обладают антиретровирусным действием.Compounds of Formula Offered
where R 1 and R 9 are independently hydrogen, acyl, unsubstituted or substituted alkyl, sulfo or sulfonyl, substituted by unsubstituted or substituted alkyl, aryl or heterocyclyl, provided that at most one of the radicals R 1 and R 9 is hydrogen; R 2 and R 8 are, respectively, independently of one another, hydrogen or unsubstituted or substituted alkyl; R 3 and R 4 are independently hydrogen, unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl or aryl; R 5 is acyloxy; R 6 is hydrogen; R 7 is unsubstituted or substituted alkyl, unsubstituted or substituted cycloalkyl or aryl, as well as salts of compounds in the presence of salt-forming groups. These compounds have antiretroviral effects.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CH3942/920 | 1992-12-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| RU93056850A true RU93056850A (en) | 1996-12-27 |
Family
ID=
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| RU93004417A (en) | NEW ARYL CYCLOALKYL DERIVATIVES, METHODS FOR THEIR PRODUCTION AND USE | |
| RU92004429A (en) | DERIVATIVES 2- (1-PIPERASINIL) -4-PHENYL-CYCLO-ALKANOPYRIDINE | |
| RU93005057A (en) | PHARMACEUTICAL COMPOUNDS, THYENOBENZODIAZEPINE DERIVATIVES, METHOD FOR THEIR PRODUCTION, PHARMOCOMPOSITION AND THEIR USE | |
| RU95120168A (en) | INDOLIN-2-SHE DERIVATIVES AND INTERMEDIATE PRODUCTS FOR THEIR PRODUCTION | |
| FR2390537A1 (en) | MIXTURES OF OPTICAL BLENZERS DERIVED FROM STILBENE | |
| ATE143004T1 (en) | ANTIRETROVIRAL HYDRAZINE DERIVATIVES | |
| MX9306588A (en) | ANTIRRETROVIRAL ACYL COMPOUND. | |
| RU96112760A (en) | 3'-OXIMINO-2 ', 3'-DIDEOSOXYNUCLEOSIDE AND THEIR DERIVATIVES | |
| RU93056850A (en) | ANTIRETROVIRAL HYDRAZINE DERIVATIVES | |
| ATE108801T1 (en) | ANTICOAGULATING PEPTIDE ALCOHOLS. | |
| RU93046319A (en) | NEW DERIVATIVES OF 3,4-DIHYDROISOCHINOLINE, METHOD FOR PRODUCING THEM, AND NEW PHARMACEUTICAL APPLICATION OF CARBOCYCLICALLY AND HETEROCYCLICALLY ANNELATED DIGYDROPYRIDINES | |
| FI903230A0 (en) | PROOF OF ORIGINATION WITHOUT WASHING. | |
| RU92004377A (en) | DERIVATIVES BIS- (PHENIL) ETHANE | |
| KR880009909A (en) | 2-aminoacetamide derivative | |
| DE3888727D1 (en) | Use of ethylamine derivatives as antihypertensive agents. | |
| FI872980A (en) | ISOKINOLINFOERENINGAR, VILKA HAR EN KVAEVESUBSTITUENT I 4-POSITIONEN OCH VILKA HAR KARDIOTONA FOSFODIESTERASFRAKTION III-INHIBERADE EGENSKAPER OCH / ELLER NJURVASODILATORISKA EGENSKAPER. | |
| DE3876193D1 (en) | AMINOMETHYL DERIVATIVES OF MONO- AND DITHIOCARBAMATES AS LUBRICANT ADDITIVES. | |
| ATE91881T1 (en) | USE OF TREQUINSIN AND COSMETIC AGENTS BASED ON THIS COMPOUND. | |
| ATE24906T1 (en) | PYRAZOLIDINEDIONE DERIVATIVES WITH VASODIDILATING, ANTI-AGGREGATIONAL AND HYPOCHOLESTEROLEMIC ACTIVITIES. | |
| ES2097222T3 (en) | AQUEOUS, STABLE AND HOMOGENEOUS FORMULATIONS OF SURFACE AGENTS. | |
| IT1251500B (en) | STABILIZATION AFTER TREATMENT OF PHOTOTHERMOGRAPHIC EMULSIONS | |
| RU93048166A (en) | ANTIRETROVIRAL ACYL COMPOUNDS | |
| RU94007096A (en) | DERIVATIVES OF ACYLOXYHEXANIC ACID | |
| RU93054009A (en) | HISPIDOSPERMIDINE | |
| KR940005807A (en) | How to tan leather and fur |