RU93053992A - METHOD FOR CLEANING AND STORING FACTOR IX, WATER SOLUTION OF PURIFIED FACTOR IX, COMPOSITION CONTAINING FACTOR IX, METHOD OF TREATMENT - Google Patents
METHOD FOR CLEANING AND STORING FACTOR IX, WATER SOLUTION OF PURIFIED FACTOR IX, COMPOSITION CONTAINING FACTOR IX, METHOD OF TREATMENTInfo
- Publication number
- RU93053992A RU93053992A RU93053992/14A RU93053992A RU93053992A RU 93053992 A RU93053992 A RU 93053992A RU 93053992/14 A RU93053992/14 A RU 93053992/14A RU 93053992 A RU93053992 A RU 93053992A RU 93053992 A RU93053992 A RU 93053992A
- Authority
- RU
- Russia
- Prior art keywords
- factor
- purified
- cleaning
- treatment
- composition containing
- Prior art date
Links
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 title claims 2
- 238000004140 cleaning Methods 0.000 title 1
- 102100006624 F9 Human genes 0.000 claims 6
- 108010076282 Factor IX Proteins 0.000 claims 6
- 229960004222 factor IX Drugs 0.000 claims 5
- 238000002360 preparation method Methods 0.000 claims 2
- 238000000746 purification Methods 0.000 claims 2
- 108010023321 Factor VII Proteins 0.000 claims 1
- 102000035443 Peptidases Human genes 0.000 claims 1
- 108091005771 Peptidases Proteins 0.000 claims 1
- 210000002381 Plasma Anatomy 0.000 claims 1
- 239000004365 Protease Substances 0.000 claims 1
- 238000006243 chemical reaction Methods 0.000 claims 1
- 230000000694 effects Effects 0.000 claims 1
- 102000004169 proteins and genes Human genes 0.000 claims 1
- 108090000623 proteins and genes Proteins 0.000 claims 1
- 150000003839 salts Chemical class 0.000 claims 1
- 239000011780 sodium chloride Substances 0.000 claims 1
- 230000000087 stabilizing Effects 0.000 claims 1
Claims (1)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US66292791A | 1991-03-01 | 1991-03-01 | |
US662,927 | 1991-03-01 | ||
US662927 | 1991-03-01 | ||
PCT/US1992/001600 WO1992015324A1 (en) | 1991-03-01 | 1992-02-26 | Preparation of factor ix |
Publications (2)
Publication Number | Publication Date |
---|---|
RU93053992A true RU93053992A (en) | 1996-10-10 |
RU2142806C1 RU2142806C1 (en) | 1999-12-20 |
Family
ID=24659784
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
RU93053992A RU2142806C1 (en) | 1991-03-01 | 1992-02-26 | Method of purification and storage of, aqueous solution of purified factor ix, composition containing factor ix, and method of treatment |
Country Status (17)
Country | Link |
---|---|
US (3) | US6063909A (en) |
EP (1) | EP0573605B1 (en) |
JP (1) | JP3418621B2 (en) |
AT (1) | ATE195877T1 (en) |
AU (1) | AU671586B2 (en) |
BR (1) | BR9205700A (en) |
CA (1) | CA2105282C (en) |
DE (1) | DE69231401T2 (en) |
DK (1) | DK0573605T3 (en) |
ES (1) | ES2150914T3 (en) |
FI (1) | FI114969B (en) |
GR (1) | GR3034946T3 (en) |
MX (1) | MX9200882A (en) |
NO (1) | NO315856B1 (en) |
RU (1) | RU2142806C1 (en) |
SG (1) | SG48282A1 (en) |
WO (1) | WO1992015324A1 (en) |
Families Citing this family (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK0573605T3 (en) * | 1991-03-01 | 2001-01-02 | Rhone Poulenc Rorer Int | Preparation of Factor IX |
WO1994005692A1 (en) * | 1992-08-27 | 1994-03-17 | Stichting Centraal Laboratorium Van De Bloedtransfusiedienst Van Het Nederlandse Rode Kruis | Antibodies specific for a haemostatic protein, their use for isolating intact protein, haemostatic compositions devoid of proteolytic cleavage products of the protein |
DE19506633A1 (en) * | 1995-02-25 | 1996-08-29 | Octapharma Ag | Process for the preparation of factor IX from biological sources |
WO1998018957A1 (en) * | 1996-10-31 | 1998-05-07 | Roche Diagnostics Gmbh | METHOD FOR DETERMINING THE CATALYTIC ACTIVITY OF FACTOR IXa |
WO2002040544A2 (en) * | 2000-11-14 | 2002-05-23 | Board Of Regents, University Of Texas Systems | Mutant human factor ix with an increased resistance to inhibition by heparin |
US20050008580A1 (en) * | 2003-04-09 | 2005-01-13 | Wyeth | Hemophilia treatment by inhalation of coagulation factors |
WO2006017263A1 (en) | 2004-07-12 | 2006-02-16 | Taro Pharmaceutical Industries Ltd. | Topical gel formulation comprising organophosphate insecticide and its preparation thereof |
US8158139B2 (en) * | 2004-07-12 | 2012-04-17 | Taro Pharmaceuticals North America, Inc. | Topical gel formulation comprising organophosphate insecticide and preparation thereof |
US7560445B2 (en) * | 2005-07-06 | 2009-07-14 | Taro Pharmaceuticals North America, Inc. | Process for preparing malathion for pharmaceutical use |
WO2011086197A1 (en) | 2010-01-18 | 2011-07-21 | Novo Nordisk Health Care Ag | Purification of blood coagulation factors |
JP5876868B2 (en) * | 2010-03-30 | 2016-03-02 | オクタファルマ・アーゲー | Method for purifying vitamin K-dependent protein such as IX coagulation factor |
US9488625B2 (en) | 2010-12-15 | 2016-11-08 | Baxalta GmbH | Purification of factor VIII using a conductivity gradient |
US9663553B2 (en) | 2014-01-29 | 2017-05-30 | Hemarus Therapeutics Limited | Integrated process for the production of therapeutics (human albumin, immunoglobulins, clotting factor VIII and clotting factor IX) from human plasma |
Family Cites Families (21)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT368883B (en) * | 1980-07-22 | 1982-11-25 | Immuno Ag | METHOD FOR PRODUCING A NEW HUMAN PROTEIN-BASED PREPARATION PROCESSING BLOOD |
DE3045153A1 (en) * | 1980-11-29 | 1982-07-08 | Behringwerke Ag, 3550 Marburg | METHOD FOR THE PRODUCTION OF BLOOD COagulation FACTORS AND THE PREPARATION OF FACTORS IX AND X THEREFORE PRODUCED |
DE3101752A1 (en) * | 1981-01-21 | 1982-08-26 | Behringwerke Ag, 3550 Marburg | "METHOD FOR PURIFYING THE BLOOD COAGINING FACTORS II, VII, IX AND / OR X AND PREPARATIONS PRODUCED THEREFORE" |
US4447416A (en) * | 1982-04-28 | 1984-05-08 | American National Red Cross | Plasma protein concentrates of reduced thrombogenicity and their use in clinical replacement therapy |
US4379085A (en) * | 1982-05-14 | 1983-04-05 | American National Red Cross | Heat stabilization of plasma proteins |
US5614500A (en) | 1983-03-04 | 1997-03-25 | The Scripps Research Institute | Compositions containing highly purified factor IX proteins prepared by immunoaffinity chromatography |
EP0118256B1 (en) * | 1983-03-04 | 1992-05-13 | Scripps Clinic And Research Foundation | Immunoadsorbent, and method of recovering vitamin-k dependent protein therewith |
US5055557A (en) * | 1983-03-04 | 1991-10-08 | Scripps Clinic & Research Foundation | Ultrapurification of factor IX and other vitamin K-dependent proteins |
ATE36457T1 (en) * | 1983-05-02 | 1988-09-15 | Immuno Ag | METHOD OF INACTIVATING REPRODUCTIVE pathogens. |
JPS60132912A (en) * | 1983-12-21 | 1985-07-16 | Kao Corp | Shampoo composition |
ATE74164T1 (en) * | 1985-04-22 | 1992-04-15 | Genetics Inst | MANUFACTURING WITH HIGH PERFORMANCE OF ACTIVE FACTOR IX. |
US4786726A (en) * | 1986-01-06 | 1988-11-22 | Blood Systems, Inc. | Factor IX therapeutic blood product, means and methods of preparing same |
FR2600334B1 (en) | 1986-06-23 | 1989-05-12 | Transgene Sa | VECTORS FOR INTEGRATION INTO EUKARYOTIC CELLS PROVIDING EXPRESSION OF FACTOR IX, CELULLAR LINES OBTAINED AND PROCESS FOR THEIR PREPARATION |
US4725673A (en) * | 1986-08-29 | 1988-02-16 | Alpha Therapeutic Corporation | Plasma fraction purification using silica resin bound to a ligand |
DE3877529T2 (en) | 1987-10-23 | 1996-11-07 | Centre Regional De Transfusion | Production of highly purified human factor IX and other plasma protein concentrate and its therapeutic use. |
JPH01258700A (en) | 1988-04-05 | 1989-10-16 | Green Cross Corp:The | Purification of blood coagulation ix factor |
DE3826792C1 (en) * | 1988-08-06 | 1989-07-06 | Biotest Pharma Gmbh, 6072 Dreieich, De | |
US4981952A (en) * | 1988-10-04 | 1991-01-01 | Eli Lilly And Company | Method for the purification of vitamin K-dependent proteins |
DE3914869C1 (en) * | 1989-05-05 | 1990-08-09 | Biotest Pharma Gmbh, 6072 Dreieich, De | |
AT402261B (en) * | 1991-01-25 | 1997-03-25 | Immuno Ag | COMPLEX CONTAINING THE coagulation factor IX |
DK0573605T3 (en) * | 1991-03-01 | 2001-01-02 | Rhone Poulenc Rorer Int | Preparation of Factor IX |
-
1992
- 1992-02-26 DK DK92908513T patent/DK0573605T3/en active
- 1992-02-26 WO PCT/US1992/001600 patent/WO1992015324A1/en active IP Right Grant
- 1992-02-26 AU AU16429/92A patent/AU671586B2/en not_active Ceased
- 1992-02-26 EP EP92908513A patent/EP0573605B1/en not_active Expired - Lifetime
- 1992-02-26 JP JP50823092A patent/JP3418621B2/en not_active Expired - Fee Related
- 1992-02-26 CA CA002105282A patent/CA2105282C/en not_active Expired - Fee Related
- 1992-02-26 RU RU93053992A patent/RU2142806C1/en active
- 1992-02-26 DE DE69231401T patent/DE69231401T2/en not_active Expired - Fee Related
- 1992-02-26 BR BR9205700A patent/BR9205700A/en not_active Application Discontinuation
- 1992-02-26 SG SG1996008689A patent/SG48282A1/en unknown
- 1992-02-26 ES ES92908513T patent/ES2150914T3/en not_active Expired - Lifetime
- 1992-02-26 AT AT92908513T patent/ATE195877T1/en not_active IP Right Cessation
- 1992-02-28 MX MX9200882A patent/MX9200882A/en unknown
-
1993
- 1993-08-03 US US08/101,175 patent/US6063909A/en not_active Expired - Lifetime
- 1993-09-01 NO NO19933114A patent/NO315856B1/en not_active IP Right Cessation
- 1993-09-01 FI FI933814A patent/FI114969B/en not_active IP Right Cessation
-
1995
- 1995-06-06 US US08/465,867 patent/US6043215A/en not_active Expired - Lifetime
-
2000
- 2000-03-13 US US09/524,206 patent/US6280729B1/en not_active Expired - Fee Related
- 2000-11-30 GR GR20000402648T patent/GR3034946T3/en not_active IP Right Cessation
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