RU93004902A - COMPOSITION OF PROLONGED CONTROLLED SURVIVAL OF PEPTIDE MEDICINE SUBSTANCE AND METHOD OF ITS OBTAINING - Google Patents

COMPOSITION OF PROLONGED CONTROLLED SURVIVAL OF PEPTIDE MEDICINE SUBSTANCE AND METHOD OF ITS OBTAINING

Info

Publication number
RU93004902A
RU93004902A RU93004902/14A RU93004902A RU93004902A RU 93004902 A RU93004902 A RU 93004902A RU 93004902/14 A RU93004902/14 A RU 93004902/14A RU 93004902 A RU93004902 A RU 93004902A RU 93004902 A RU93004902 A RU 93004902A
Authority
RU
Russia
Prior art keywords
composition
obtaining
peptide medicine
prolonged controlled
medicine substance
Prior art date
Application number
RU93004902/14A
Other languages
Russian (ru)
Other versions
RU2103994C1 (en
Inventor
Ф.Хаймгартнер
П.Орсолини
Original Assignee
Аста Медика Аг
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from CH2178/91A external-priority patent/CH683149A5/en
Application filed by Аста Медика Аг filed Critical Аста Медика Аг
Publication of RU93004902A publication Critical patent/RU93004902A/en
Application granted granted Critical
Publication of RU2103994C1 publication Critical patent/RU2103994C1/en

Links

Claims (1)

Композиция предназначена для пролонгированного контролируемого введения пептидного лекарственного вещества формулы Ac-D-NaI-D - pCIPhe-R3 - Ser-Tyr-D-Cit-Leu - Arg-Pro-D-AIa - NH2, в которой R3 означает D-PaI или D-Trp. Способ получения композиция заключается в том, что ее получают в виде микросфер из полимерного материала, поддающегося биологическому разложению, вмещающих нерастворимую в воде соль пептида указанной формулы.The composition is intended for prolonged controlled administration of a peptide drug substance of the formula Ac-D-NaI-D - pCIPhe-R 3 - Ser-Tyr-D-Cit-Leu - Arg-Pro-D-AIa - NH 2 , in which R 3 means D -PaI or D-Trp. The method of obtaining the composition lies in the fact that it is obtained in the form of microspheres from a polymeric material that can be biodegradable, containing the water-insoluble peptide salt of the specified formula.
RU93004902A 1991-07-22 1992-07-15 Composition in the form of microspheres for prolonged and controlled release of peptide medicinal substance RU2103994C1 (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
CH2178/91 1991-07-22
CH2178/91A CH683149A5 (en) 1991-07-22 1991-07-22 Process for the preparation of microspheres of a biodegradable polymeric material.
PCT/CH1992/000146 WO1993001802A1 (en) 1991-07-22 1992-07-15 Composition for the sustained and controlled release of a medicinal peptide-containing substance, and preparation method therefor

Publications (2)

Publication Number Publication Date
RU93004902A true RU93004902A (en) 1995-05-10
RU2103994C1 RU2103994C1 (en) 1998-02-10

Family

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Family Applications (1)

Application Number Title Priority Date Filing Date
RU93004902A RU2103994C1 (en) 1991-07-22 1992-07-15 Composition in the form of microspheres for prolonged and controlled release of peptide medicinal substance

Country Status (40)

Country Link
US (2) US5445832A (en)
JP (2) JP3600252B2 (en)
KR (1) KR930702018A (en)
CN (1) CN1054543C (en)
AT (2) AT408609B (en)
AU (2) AU652844B2 (en)
BE (2) BE1005696A3 (en)
BR (1) BR9205375A (en)
CA (2) CA2074320C (en)
CH (2) CH683149A5 (en)
CZ (1) CZ287585B6 (en)
DE (3) DE4223284C2 (en)
DK (2) DK176219B1 (en)
EE (1) EE03014B1 (en)
ES (2) ES2037621B1 (en)
FI (2) FI105318B (en)
FR (2) FR2680109B1 (en)
GB (2) GB2257909B (en)
GR (2) GR1002548B (en)
HR (1) HRP920229A2 (en)
HU (1) HU218203B (en)
IE (2) IE71199B1 (en)
IL (2) IL102590A (en)
IT (2) IT1259891B (en)
LU (2) LU88150A1 (en)
MX (1) MX9204268A (en)
NL (2) NL194577C (en)
NO (2) NO304057B1 (en)
NZ (1) NZ243643A (en)
PH (1) PH31564A (en)
PL (1) PL169387B1 (en)
PT (2) PT100713B (en)
RU (1) RU2103994C1 (en)
SE (2) SE512670C2 (en)
SI (1) SI9200152B (en)
SK (1) SK280612B6 (en)
TW (1) TW260610B (en)
UA (1) UA35569C2 (en)
WO (1) WO1993001802A1 (en)
ZA (2) ZA925485B (en)

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