RU2793513C1 - Method for treatment of skin scars soldered to underlying tissues - Google Patents

Abstract

FIELD: medicine.

SUBSTANCE: invention relates to dermatology and cosmetology, and can be used to treat skin scars, in particular, atrophic scars complicated by the presence of adhesions. Radio wave defibrosis of scar tissue is performed using an RF cannula. The frequency of radio wave radiation is 1–2 MHz, the power is up to 2 watts. Simultaneously with exposure to radio wave radiation, autoplasma or platelet-rich autoplasma is injected through the said RF cannula in an amount of 0.1–0.2 ml per 1 mm² of scar tissue surface.

EFFECT: invention provides effective removal of adhesive scars with achievement of maximum cosmetic effect, due to such a complex effect on scar tissue.

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Description

The invention relates to the field of cosmetology and dermatology and can be used for the treatment of atrophic scars of the skin, in particular, soldered to the underlying tissues.

Skin fibrosis is a disease characterized by an accelerated process of collagen production and the growth of secondary morphological elements that occur after trauma, surgery or inflammation. This disease is increasingly common in cosmetology. After destruction, the skin has a focal pathological change. It is an overgrown connective tissue with an unbalanced distribution of functional changes. The degree of fibrosis is caused by the ratio of collagen synthesis and breakdown. In medical practice, it is often possible to observe patients with post-procedural fibrotic changes. These can be fibrous canals caused by contouring, fibrous scaffolds that appeared after thread reinforcement, as well as cicatricial changes of various origins. It is important to note that in the process of aging, formed fibrosis occurs in the form of adhesions in places of hypodermal and dermal creases. Moreover, it is a non-pathological physiological change. The specified fibrosis in the form of adhesions is difficult to correct.

Traditional treatments for fibrosis suggest the use of drugs that contain components that destroy connective fibers. In addition, the practice of mechanical separation of such fibrotic changes as adhesions and scars is used. The use of drugs in the form of solutions in this case is often difficult due to their uncontrolled distribution. For example, in the practice of clinical applications, patients often encounter complications in the form of various atrophic changes. Moreover, they are caused by the use of solutions in pathological connective tissue.

It is also important that when working with conventional separation there is an additional risk. Indeed, in post-procedural patients, it is performed in places where fibrosis has already been formed. Therefore, additional trauma often leads to activation of connective tissue synthesis and internal scarring.

In the prior art, various methods for the treatment of atrophic scars of the skin are known. In particular, from RU 2230554, 20.06.2004, a method is known for treating normo-atrophic skin scars by carrying out a complex of preoperative measures and dermabrasion, characterized in that the operation area is exposed on an outpatient basis under sterile conditions of a small operating room, the skin surface is treated twice with butol, 10 ml each, using gauze napkin, capturing more than 2-3 cm of the operating area, and local anesthesia is performed with lidocaine, then dermabrasion is performed using a rotary apparatus and the skin surfaces are treated by applying a gauze napkin pre-moistened with butol, the surgical wound is treated with butol twice 10-15 ml from a plastic syringe without a needle, and 3-5 minutes after the patient's burning sensation disappears, a gauze napkin is removed with a forceps, after dermabrasion, a collagen coating is applied to the operating surface, which exceeds the operating area by 1-2 cm, and the operating wound is treated twice without interruption with butol according to 10-15 ml from a plastic syringe without a needle and the operating surface are irradiated with infrared radiation of low power 5-8 times a day, and in the postoperative period for 7-10 days, gauze bandages with butol are douched several times a day until the epidermis heals and spontaneous removal of the scab . This method is relatively laborious and not efficient enough.

From RU 2524655, 07/27/2014, an agent is known for the treatment of a skin scar, in particular a keloid, a hypertrophic scar and a scar contracture, containing basic fibroblast growth factor (bFGF) as the only active ingredient for the treatment of a skin scar, which is administered intradermally or subcutaneously at the site of the scar , which is the object of treatment, or in the surrounding part. The specified tool is not effective enough (see example 3, Fig.7-8).

The closest analogue of the claimed invention is a method known from patent RU 2627468, 08.08.2017 for the treatment of atrophic skin scars using fully rectified filtered high-frequency radio waves and autologous platelet-rich plasma, characterized in that blood is taken from the patient's peripheral vein into vacuum tubes, mixed blood with an anticoagulant, centrifuge the mixture of blood with an anticoagulant for 4-6 minutes at a centrifuge speed of 700-900 rpm, remove the upper layer of the formed platelet-rich plasma from the tube into a separate tube, activate the platelet-rich plasma with calcium ions by adding calcium gluconate and mixing with it, activated platelet-rich plasma is drawn into a syringe and injected intradermally into the scar, the injected area is heated using the Surgitron® radio wave apparatus with Pelleve GlideSafe or PelleFirm electrodes to 41-43°C for at least 4 minutes. The disadvantage of this method is the low efficiency in the case of scars complicated by the presence of adhesions.

The objective of the invention is the effective removal of adhesive scars to achieve the maximum cosmetic effect.

The technical result of the claimed invention is to increase the efficiency of removing scars complicated by the presence of adhesions.

To achieve this result, a method is proposed for the treatment of adhesive scars of the skin, including radio wave defibrosis of scar tissue using an RF cannula at a frequency of radio wave radiation of 1-2 MHz and a power of up to 2 W, characterized in that simultaneously with exposure to radio wave radiation, an injection is made through the specified RF cannula autoplasma or platelet-rich autoplasma in the amount of 0.1-0.2 ml per 1 mm ² of the scar tissue surface.

When implementing the method, heating occurs, which destroys scar tissue and old collagen, loosens and changes the state of collagen fibers. During the session, exposure to high-frequency waves warms up the lower layers of the skin and subcutaneous fat, which activates the processes of thermoregulation. The temperature of the treated area rises, the vessels dilate, the tissues receive more oxygen, by accelerating metabolism, metabolic products are more actively removed and the production of new collagen is stimulated. Due to the radio wave in the range of 1-2 MHz, an internal temperature of up to 50°C is formed in the affected area. This induces the manifestation of heat shock protein (chaperone) HSP47 in fibroblasts, which contributes to the optimal spatial packing of protein molecules without causing coagulation. At the same time, since autoplasma or autoplasma enriched with platelets is introduced simultaneously with heating, the tissues do not have time to undergo repeated fibrosis or the onset of scarring, i.e. the spatial packing of protein molecules does not have time to return to the previous state (pathologically produced collagen) and the process of formation of fibrous-altered scar tissue does not have time to start, which can happen if there is a time interval between exposure to radio wave radiation and the introduction of autoplasma. If there is a specified time interval between exposure to radio wave radiation and the introduction of autoplasma, the introduction of autoplasma will be less effective, since in this time interval the formation of fibrous-altered scar tissue begins, which will hinder the production of new collagen and lead to a decrease in the cosmetic effect.

The method was applied in clinical conditions in 25 patients with cicatricial adhesive deformities of the skin aged 20 to 50 years. All patients were female.

All patients showed a significant smoothing of the skin relief and the disappearance of scars.

Example 1

Patient A came to the clinic with cicatricial pathology in the lower leg. On examination, there is a mixed extensive scar with a soldered bottom for almost the entire lower leg. Treatment was carried out, including radio wave defibrosis of scar tissue using a 19G RF cannula at a radio wave frequency of 1 MHz and a power of 2 W. Simultaneously with the exposure to radio wave radiation, autoplasma was introduced through the specified RF cannula in an amount of 0.2 ml per 1 mm ² of the scar tissue surface (20 ml in total). A month after the procedure, the skin relief leveled off and the complete disappearance of the scar was observed. The results are presented in Fig.1.

Example 2

Patient B presented with a scar in the lip area after severe paresis. An atrophic scar with an adhesion formed. Radio wave defibrosis of scar tissue was performed using a 21G RF cannula at a radio wave frequency of 2 MHz and a power of 1 W. Simultaneously with the exposure to radio wave radiation, platelet-enriched autoplasma was introduced through the indicated RF cannula in the amount of 0.1 ml per 1 mm ² of the scar tissue surface. A month after the procedure, the skin relief leveled off and the disappearance of the scar with adhesions was observed. The results are shown in figure 2 (top photo - before treatment, bottom photo - after).

The presented examples confirm the achievement of the technical result, namely, the high efficiency of removing scars complicated by the presence of adhesions, with the achievement of the maximum cosmetic effect.

Claims (1)

A method for treating skin scars welded to underlying tissues, including radio wave defibrosis of scar tissue using an RF cannula at a frequency of radio wave radiation of 1-2 MHz and a power of up to 2 W, characterized in that, simultaneously with exposure to radio wave radiation, autoplasma is introduced through the specified RF cannula or platelet-enriched autoplasma in the amount of 0.1-0.2 ml per 1 mm ² of the scar tissue surface.

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