RU2767784C2 - АНТИ-GARP-TGF-β-АНТИТЕЛА - Google Patents
АНТИ-GARP-TGF-β-АНТИТЕЛА Download PDFInfo
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- RU2767784C2 RU2767784C2 RU2019140602A RU2019140602A RU2767784C2 RU 2767784 C2 RU2767784 C2 RU 2767784C2 RU 2019140602 A RU2019140602 A RU 2019140602A RU 2019140602 A RU2019140602 A RU 2019140602A RU 2767784 C2 RU2767784 C2 RU 2767784C2
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- tgf
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| GB1707561.5 | 2017-05-11 | ||
| PCT/EP2018/062251 WO2018206790A1 (en) | 2017-05-11 | 2018-05-11 | GARP-TGF-β ANTIBODIES |
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| EP3960855A1 (en) * | 2001-12-28 | 2022-03-02 | Chugai Seiyaku Kabushiki Kaisha | Method for stabilizing proteins |
| US11046782B2 (en) * | 2016-03-30 | 2021-06-29 | Musc Foundation For Research Development | Methods for treatment and diagnosis of cancer by targeting glycoprotein A repetitions predominant (GARP) and for providing effective immunotherapy alone or in combination |
| KR102376605B1 (ko) | 2019-08-28 | 2022-03-21 | 추가이 세이야쿠 가부시키가이샤 | 종교차성 항잠재형 TGF-β1 항체 및 사용 방법 |
| US20240190961A1 (en) | 2019-10-25 | 2024-06-13 | Daiichi Sankyo Company, Limited | Combination of anti-garp antibody and immunomodulator |
| MX2022008609A (es) * | 2020-01-11 | 2022-11-10 | Scholar Rock Inc | Inhibidores de tgf¿ y uso de los mismos. |
| CN115243724B (zh) | 2020-02-19 | 2025-10-21 | 纳米医疗有限公司 | 可用于治疗癌症的经调配和/或共调配的含有TFGβ拮抗剂前药的脂质体组合物和其方法 |
| US20230192867A1 (en) * | 2020-05-15 | 2023-06-22 | Bristol-Myers Squibb Company | Antibodies to garp |
| AU2021380681A1 (en) * | 2020-11-11 | 2023-06-15 | Versapeutics Inc. | Antibody variants against wnt receptor ryk |
| AU2021391054A1 (en) * | 2020-12-02 | 2023-06-22 | Shanghai Henlius Biotech, Inc. | ANTI-GARP/TGFβ ANTIBODIES AND METHODS OF USE |
| BR112023014319A2 (pt) * | 2021-01-18 | 2023-09-26 | Jiangxi Jemincare Group Co Ltd | Anticorpo contra a proteína garp e aplicação do mesmo |
| EP4526330A1 (en) | 2022-05-18 | 2025-03-26 | Vestaron Corporation | Pesticidal actx peptide variants |
| JP2025526336A (ja) | 2022-07-22 | 2025-08-13 | アンスティチュ ナショナル ドゥ ラ サンテ エ ドゥ ラ ルシェルシュ メディカル | Ｔ細胞悪性腫瘍におけるバイオマーカー及びバイオターゲットとしてのｇａｒｐ |
| CN119630418A (zh) | 2022-07-29 | 2025-03-14 | 艾伯维生物制药股份有限公司 | 抗GARP-TGF-β1/PD-1组合疗法 |
| WO2024149237A1 (zh) | 2023-01-09 | 2024-07-18 | 北京拓界生物医药科技有限公司 | TGFβ1结合分子、GARP-TGFβ1结合分子及其医药用途 |
| WO2024164807A1 (zh) * | 2023-02-06 | 2024-08-15 | 贝达药业股份有限公司 | 多特异性抗体及其应用 |
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| RU2455358C2 (ru) * | 2003-08-22 | 2012-07-10 | Проекто Де Биомедисина Сима, С.Л. | ПРИМЕНЕНИЕ ПОСЛЕДОВАТЕЛЬНОСТИ ДНК, КОТОРАЯ КОДИРУЕТ ПЕПТИД, СПОСОБНЫЙ СВЯЗЫВАТЬСЯ С ТРАНСФОРМИРУЮЩИМ ФАКТОРОМ РОСТА β1 (ВАРИАНТЫ) |
| WO2015015003A1 (en) * | 2013-08-01 | 2015-02-05 | Université Catholique de Louvain | Anti-garp protein and uses thereof |
| WO2016125017A1 (en) * | 2015-02-03 | 2016-08-11 | Universite Catholique De Louvain | Anti-garp protein and uses thereof |
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| US4816567A (en) | 1983-04-08 | 1989-03-28 | Genentech, Inc. | Recombinant immunoglobin preparations |
| US5892019A (en) | 1987-07-15 | 1999-04-06 | The United States Of America, As Represented By The Department Of Health And Human Services | Production of a single-gene-encoded immunoglobulin |
| DE3920358A1 (de) | 1989-06-22 | 1991-01-17 | Behringwerke Ag | Bispezifische und oligospezifische, mono- und oligovalente antikoerperkonstrukte, ihre herstellung und verwendung |
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| EP2890711B1 (en) | 2012-08-31 | 2017-01-04 | Argen-X Nv | Method for producing antibody molecules having inter-species, intra-target cross-reactivity |
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| AU2016325858B2 (en) | 2015-09-24 | 2022-05-26 | Daiichi Sankyo Company, Limited | Anti-GARP antibody |
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2017
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