RU2759945C2 - Гранулы, используемые в клеточной культуре, и способы их получения - Google Patents

Гранулы, используемые в клеточной культуре, и способы их получения Download PDF

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Publication number
RU2759945C2
RU2759945C2 RU2018124447A RU2018124447A RU2759945C2 RU 2759945 C2 RU2759945 C2 RU 2759945C2 RU 2018124447 A RU2018124447 A RU 2018124447A RU 2018124447 A RU2018124447 A RU 2018124447A RU 2759945 C2 RU2759945 C2 RU 2759945C2
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RU
Russia
Prior art keywords
cell culture
granule
powder
soluble
culture medium
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RU2018124447A
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English (en)
Russian (ru)
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RU2018124447A (ru
RU2018124447A3 (enExample
Inventor
Мвита ФЕЛПС
Пол ГУЛД
Ричард ФАЙК
Мэри РЕЙНОЛДЗ
Ричард ХАССЕТТ
Эндрю КЭМПБЕЛЛ
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Лайф Текнолоджиз Корпорейшн
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Publication of RU2018124447A publication Critical patent/RU2018124447A/ru
Publication of RU2018124447A3 publication Critical patent/RU2018124447A3/ru
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J8/00—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
    • B01J8/18—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles
    • B01J8/1845—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles with particles moving upwards while fluidised
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/16—Vibrating; Shaking; Tilting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/18—Flow directing inserts
    • C12M27/20—Baffles; Ribs; Ribbons; Auger vanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M99/00—Subject matter not otherwise provided for in other groups of this subclass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/22—Processes using, or culture media containing, cellulose or hydrolysates thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Combustion & Propulsion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sustainable Development (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
RU2018124447A 2015-12-17 2016-12-16 Гранулы, используемые в клеточной культуре, и способы их получения RU2759945C2 (ru)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562269031P 2015-12-17 2015-12-17
US62/269,031 2015-12-17
PCT/US2016/067374 WO2017106783A1 (en) 2015-12-17 2016-12-16 Pellets used in cell culture and methods of making thereof

Related Child Applications (1)

Application Number Title Priority Date Filing Date
RU2021132093A Division RU2021132093A (ru) 2015-12-17 2016-12-16 Гранулы, используемые в клеточной культуре, и способы их получения

Publications (3)

Publication Number Publication Date
RU2018124447A RU2018124447A (ru) 2020-01-22
RU2018124447A3 RU2018124447A3 (enExample) 2020-11-06
RU2759945C2 true RU2759945C2 (ru) 2021-11-19

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Family Applications (2)

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RU2018124447A RU2759945C2 (ru) 2015-12-17 2016-12-16 Гранулы, используемые в клеточной культуре, и способы их получения
RU2021132093A RU2021132093A (ru) 2015-12-17 2016-12-16 Гранулы, используемые в клеточной культуре, и способы их получения

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Country Status (8)

Country Link
US (2) US10822584B2 (enExample)
EP (2) EP4036220A1 (enExample)
JP (2) JP6876049B2 (enExample)
KR (1) KR20180091923A (enExample)
CN (1) CN108495926A (enExample)
RU (2) RU2759945C2 (enExample)
SG (1) SG11201805049TA (enExample)
WO (1) WO2017106783A1 (enExample)

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WO2020218584A1 (ja) * 2019-04-26 2020-10-29 味の素株式会社 細胞培養用組成物
EP4031648A1 (en) * 2019-09-19 2022-07-27 Life Technologies Corporation Cell culture media tablets and methods of manufacture
US20210395698A1 (en) 2020-06-22 2021-12-23 Life Technologies Corporation Methods and compositions for cultivating pluripotent cell suspensions
US20230287334A1 (en) * 2020-07-14 2023-09-14 Corning Incorporated Rapidly dissolving cell culture media powder and methods of making the same
KR102978097B1 (ko) 2020-09-22 2026-06-17 알피니티 유에스에이, 인크. 생물공정 및 제약 용례를 위한 유체의 제조 시스템 및 방법
JP7651417B2 (ja) 2021-09-09 2025-03-26 株式会社クボタ 自動走行制御システムおよび圃場作業車
KR102633825B1 (ko) * 2021-10-18 2024-02-02 연세대학교 산학협력단 박테리아를 이용한 가스 중 질소산화물의 저감 방법 및 시스템

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EP0576903B1 (en) * 1992-06-23 1996-11-27 Shionogi & Co., Ltd. Centrifugal fluidising granulator and method for powder coating granulation
US20140273205A1 (en) * 1999-04-30 2014-09-18 Life Technologies Corporation Animal cell culture media comprising non animal or plant derived nutrients

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EP0576903B1 (en) * 1992-06-23 1996-11-27 Shionogi & Co., Ltd. Centrifugal fluidising granulator and method for powder coating granulation
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Also Published As

Publication number Publication date
SG11201805049TA (en) 2018-07-30
JP6876049B2 (ja) 2021-05-26
CN108495926A (zh) 2018-09-04
US20180142203A1 (en) 2018-05-24
JP2018537113A (ja) 2018-12-20
WO2017106783A1 (en) 2017-06-22
US10822584B2 (en) 2020-11-03
RU2018124447A (ru) 2020-01-22
US20210009942A1 (en) 2021-01-14
JP2021106613A (ja) 2021-07-29
EP3271452A1 (en) 2018-01-24
EP4036220A1 (en) 2022-08-03
KR20180091923A (ko) 2018-08-16
RU2018124447A3 (enExample) 2020-11-06
RU2021132093A (ru) 2021-12-07
JP7357657B2 (ja) 2023-10-06
EP3271452B1 (en) 2021-12-08

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