JP6876049B2 - 細胞培養に使用されるペレットおよびその製造方法 - Google Patents

細胞培養に使用されるペレットおよびその製造方法 Download PDF

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JP6876049B2
JP6876049B2 JP2018531335A JP2018531335A JP6876049B2 JP 6876049 B2 JP6876049 B2 JP 6876049B2 JP 2018531335 A JP2018531335 A JP 2018531335A JP 2018531335 A JP2018531335 A JP 2018531335A JP 6876049 B2 JP6876049 B2 JP 6876049B2
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medium
pellets
cell culture
pellet
feed
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JP2018537113A5 (enExample
JP2018537113A (ja
Inventor
ムウィタ フェルプス
ムウィタ フェルプス
ポール グルデ
ポール グルデ
リチャード ファイク
リチャード ファイク
メアリー レイノルズ
メアリー レイノルズ
リチャード ハセット
リチャード ハセット
アンドリュー キャンベル
アンドリュー キャンベル
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Life Technologies Corp
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Life Technologies Corp
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    • B—PERFORMING OPERATIONS; TRANSPORTING
    • B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01J—CHEMICAL OR PHYSICAL PROCESSES, e.g. CATALYSIS OR COLLOID CHEMISTRY; THEIR RELEVANT APPARATUS
    • B01J8/00—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes
    • B01J8/18—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles
    • B01J8/1845—Chemical or physical processes in general, conducted in the presence of fluids and solid particles; Apparatus for such processes with fluidised particles with particles moving upwards while fluidised
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/16—Vibrating; Shaking; Tilting
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00—Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/18—Flow directing inserts
    • C12M27/20—Baffles; Ribs; Ribbons; Auger vanes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12M—APPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M99/00—Subject matter not otherwise provided for in other groups of this subclass
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/22—Processes using, or culture media containing, cellulose or hydrolysates thereof
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/05—Inorganic components
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/32—Amino acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/34—Sugars
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/30—Organic components
    • C12N2500/38—Vitamins
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2500/00—Specific components of cell culture medium
    • C12N2500/60—Buffer, e.g. pH regulation, osmotic pressure

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  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biomedical Technology (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Virology (AREA)
  • Medicinal Chemistry (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Cell Biology (AREA)
  • Combustion & Propulsion (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Sustainable Development (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
JP2018531335A 2015-12-17 2016-12-16 細胞培養に使用されるペレットおよびその製造方法 Expired - Fee Related JP6876049B2 (ja)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP2021072968A JP7357657B2 (ja) 2015-12-17 2021-04-23 細胞培養に使用されるペレットおよびその製造方法

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201562269031P 2015-12-17 2015-12-17
US62/269,031 2015-12-17
PCT/US2016/067374 WO2017106783A1 (en) 2015-12-17 2016-12-16 Pellets used in cell culture and methods of making thereof

Related Child Applications (1)

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JP2021072968A Division JP7357657B2 (ja) 2015-12-17 2021-04-23 細胞培養に使用されるペレットおよびその製造方法

Publications (3)

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JP2018537113A JP2018537113A (ja) 2018-12-20
JP2018537113A5 JP2018537113A5 (enExample) 2019-12-19
JP6876049B2 true JP6876049B2 (ja) 2021-05-26

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JP2018531335A Expired - Fee Related JP6876049B2 (ja) 2015-12-17 2016-12-16 細胞培養に使用されるペレットおよびその製造方法
JP2021072968A Active JP7357657B2 (ja) 2015-12-17 2021-04-23 細胞培養に使用されるペレットおよびその製造方法

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US (2) US10822584B2 (enExample)
EP (2) EP4036220A1 (enExample)
JP (2) JP6876049B2 (enExample)
KR (1) KR20180091923A (enExample)
CN (1) CN108495926A (enExample)
RU (2) RU2759945C2 (enExample)
SG (1) SG11201805049TA (enExample)
WO (1) WO2017106783A1 (enExample)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2020218584A1 (ja) * 2019-04-26 2020-10-29 味の素株式会社 細胞培養用組成物
EP4031648A1 (en) * 2019-09-19 2022-07-27 Life Technologies Corporation Cell culture media tablets and methods of manufacture
US20210395698A1 (en) 2020-06-22 2021-12-23 Life Technologies Corporation Methods and compositions for cultivating pluripotent cell suspensions
US20230287334A1 (en) * 2020-07-14 2023-09-14 Corning Incorporated Rapidly dissolving cell culture media powder and methods of making the same
KR102978097B1 (ko) 2020-09-22 2026-06-17 알피니티 유에스에이, 인크. 생물공정 및 제약 용례를 위한 유체의 제조 시스템 및 방법
JP7651417B2 (ja) 2021-09-09 2025-03-26 株式会社クボタ 自動走行制御システムおよび圃場作業車
KR102633825B1 (ko) * 2021-10-18 2024-02-02 연세대학교 산학협력단 박테리아를 이용한 가스 중 질소산화물의 저감 방법 및 시스템

Family Cites Families (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2379001A (en) 1944-05-20 1945-06-26 Leonard W Moen Device for removing and applying chain links
SU1275042A1 (ru) * 1984-12-28 1986-12-07 Научно-Исследовательский Институт По Производству Питательных Сред, Г.Махачкала Способ производства сухих питательных сред
DE3609133A1 (de) 1986-03-19 1987-09-24 Glatt Gmbh Vorrichtung zum pelletieren od. dgl. behandeln von teilchen sowie damit durchfuehrbares verfahren
US4962091A (en) * 1986-05-23 1990-10-09 Syntex (U.S.A.) Inc. Controlled release of macromolecular polypeptides
JPH0257175A (ja) * 1988-08-19 1990-02-26 Morinaga & Co Ltd 成形培地及びその製造法
US5132142A (en) * 1991-03-19 1992-07-21 Glatt Gmbh Apparatus and method for producing pellets by layering power onto particles
JP3347366B2 (ja) * 1992-06-23 2002-11-20 塩野義製薬株式会社 転動造粒装置及び方法
EP0920490A2 (en) * 1996-07-25 1999-06-09 Genzyme Corporation Chondrocyte media formulations and culture procedures
EP2221361A3 (en) * 1996-08-30 2011-02-09 Life Technologies Corporation Method for producing a polypeptide in vitro in mammalian cells in a protein-free and serum-free culture medium
US6383810B2 (en) * 1997-02-14 2002-05-07 Invitrogen Corporation Dry powder cells and cell culture reagents and methods of production thereof
US20060286668A1 (en) * 1999-04-30 2006-12-21 Invitrogen Corporation Animal-cell culture media comprising non-animal or plant-derived nutrients
JP2001170473A (ja) * 1999-12-17 2001-06-26 Hosokawa Micron Corp 造粒装置
AU2002232406C1 (en) * 2000-11-06 2009-03-05 Invitrogen Corporation Dry powder cells and cell culture reagents and methods of production thereof
CN1657604A (zh) * 2005-02-07 2005-08-24 黄宗堂 一种培养基的配制和使用方法
FR2910024B1 (fr) * 2006-12-19 2009-03-27 Agronomique Inst Nat Rech Milieu de culture synthetique chimiquement defini.
AU2011246503B2 (en) * 2010-04-26 2013-09-26 Novartis Ag Improved cell culture medium
EP2652123B1 (en) * 2010-12-16 2016-01-13 Merck Patent GmbH Dry granulated cell culture media
KR102007997B1 (ko) 2011-02-07 2019-08-07 라이프 테크놀로지스 코포레이션 감수성 화합물을 안정화시키는 조성물 및 방법
JP6216327B2 (ja) * 2011-12-22 2017-10-18 ライフ テクノロジーズ コーポレーション 細胞培地および方法
EP2882842B1 (en) * 2012-08-07 2019-02-20 3M Innovative Properties Company Method of making agglomerated microbiological media and compositions thereof
CN104096510A (zh) * 2013-04-12 2014-10-15 上海源培生物科技有限公司 利用流化床干燥技术混匀培养基成分的工艺
US20150275167A1 (en) * 2014-03-28 2015-10-01 Corning Incorporated Composition and method for cell culture sustained release

Also Published As

Publication number Publication date
SG11201805049TA (en) 2018-07-30
CN108495926A (zh) 2018-09-04
US20180142203A1 (en) 2018-05-24
JP2018537113A (ja) 2018-12-20
WO2017106783A1 (en) 2017-06-22
US10822584B2 (en) 2020-11-03
RU2018124447A (ru) 2020-01-22
US20210009942A1 (en) 2021-01-14
JP2021106613A (ja) 2021-07-29
EP3271452A1 (en) 2018-01-24
EP4036220A1 (en) 2022-08-03
KR20180091923A (ko) 2018-08-16
RU2018124447A3 (enExample) 2020-11-06
RU2021132093A (ru) 2021-12-07
JP7357657B2 (ja) 2023-10-06
EP3271452B1 (en) 2021-12-08
RU2759945C2 (ru) 2021-11-19

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