RU2713203C1 - Режим дозирования при лечении острых обострений хронической обструктивной болезни легких - Google Patents
Режим дозирования при лечении острых обострений хронической обструктивной болезни легких Download PDFInfo
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- RU2713203C1 RU2713203C1 RU2018132047A RU2018132047A RU2713203C1 RU 2713203 C1 RU2713203 C1 RU 2713203C1 RU 2018132047 A RU2018132047 A RU 2018132047A RU 2018132047 A RU2018132047 A RU 2018132047A RU 2713203 C1 RU2713203 C1 RU 2713203C1
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- RU
- Russia
- Prior art keywords
- cyanobenzoyl
- methylbenzamide
- pyrazol
- cyclopropyl
- amino
- Prior art date
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- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
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| GB201612238D0 (en) | 2016-07-14 | 2016-08-31 | Mereo Biopharma 1 Ltd | Method for producing a polymorphic form of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-Yl]-n-cyclopropyl-4-methylbenzamide |
| GB201612240D0 (en) | 2016-07-14 | 2016-08-31 | Mereo Biopharma 1 Ltd | Method for producing a polymorphic form of 3-[5-amino-4-(3-cyanobenzoyl)-pyrazol-1-yl]-n-cyclopropyl-4-methylbenzamide |
| PT3585382T (pt) * | 2017-12-11 | 2021-08-19 | Mereo Biopharma 1 Ltd | Utilização de 3-[5-amino-4-(3-cianobenzoil)-pirazol-1-il]-n-ciclopropil-4-metilbenzamida no tratamento de exacerbações agudas da doença pulmonar obstrutiva crónica |
| KR102760007B1 (ko) * | 2017-12-11 | 2025-02-03 | 메레오 바이오파마 1 리미티드 | 만성 폐쇄성 폐 질환의 급성 악화의 예방 또는 감소에서의 3-[5-아미노-4-(3-시아노벤조일)-피라졸-1-일]-n-시클로프로필-4-메틸벤즈아미드의 용도 |
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| US6899099B2 (en) * | 1997-12-31 | 2005-05-31 | Astrazeneca Ab | Method for treating a respiratory disease |
| WO2013139809A1 (en) * | 2012-03-20 | 2013-09-26 | Novartis Ag | Use of a pyrazole derivative in the treatment of acute exacerbations of chronic obstructive pulmonary disease |
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| GB9501841D0 (en) | 1995-01-31 | 1995-03-22 | Co Ordinated Drug Dev | Improvements in and relating to carrier particles for use in dry powder inhalers |
| HRP20110757T1 (hr) | 2003-06-26 | 2011-11-30 | Novartis Ag | Inhibitori kinaze p38 bazirani na 5-članom heterociklu |
| TWI439284B (zh) | 2004-04-09 | 2014-06-01 | Abbvie Biotechnology Ltd | 用於治療ＴＮＦα相關失調症之多重可變劑量療法 |
| GB0409703D0 (en) | 2004-04-30 | 2004-06-02 | Vectura Ltd | Pharmaceutical compositions |
| US20050277602A1 (en) | 2004-05-21 | 2005-12-15 | Grunstein Michael M | Methods employing agonists of P38 map kinase for the treatment of asthma |
| EP1987022A1 (en) | 2006-02-10 | 2008-11-05 | Pfizer Products Inc. | Pyridinone pyrazole urea and pyrimidinone pyrazole urea derivatives |
| GB0603684D0 (en) * | 2006-02-23 | 2006-04-05 | Novartis Ag | Organic compounds |
| WO2017153702A1 (en) * | 2016-03-08 | 2017-09-14 | Mereo Biopharma 1 Limited | Dosage regimen for the treatment of acute exacerbations of chronic obstructive pulmonary disease |
| AU2016397046B2 (en) * | 2016-03-08 | 2022-05-12 | Mereo Biopharma 1 Limited | Dosage regimen for the treatment of acute exacerbations of inflammatory conditions |
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Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US6899099B2 (en) * | 1997-12-31 | 2005-05-31 | Astrazeneca Ab | Method for treating a respiratory disease |
| WO2013139809A1 (en) * | 2012-03-20 | 2013-09-26 | Novartis Ag | Use of a pyrazole derivative in the treatment of acute exacerbations of chronic obstructive pulmonary disease |
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| CA3016488A1 (en) | 2017-09-14 |
| KR20180118667A (ko) | 2018-10-31 |
| MX2018010782A (es) | 2019-01-10 |
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| US11129810B2 (en) | 2021-09-28 |
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| JP2019507786A (ja) | 2019-03-22 |
| MX385717B (es) | 2025-03-18 |
| BR112018067454A2 (pt) | 2019-01-15 |
| KR102762199B1 (ko) | 2025-02-07 |
| US20200281896A1 (en) | 2020-09-10 |
| AU2016397047B2 (en) | 2022-04-07 |
| US10603306B2 (en) | 2020-03-31 |
| AU2016397047A1 (en) | 2018-09-06 |
| CA3016488C (en) | 2023-04-11 |
| JP6741774B2 (ja) | 2020-08-19 |
| KR20240101698A (ko) | 2024-07-02 |
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