RU2699372C1 - Indoor air disinfection means - Google Patents

Abstract

FIELD: hygiene.SUBSTANCE: invention relates to hygiene and sanitation and can be used for indoor air disinfection and sanitation. Air disinfectant contains hydrogen peroxide, a soluble silver salt, an organic compound and water. Organic compound used is 5 % solution of furocoumarin in ethyl alcohol. Agent contains the following ratio of components, wt%: hydrogen peroxide – 5; silver salt – 1; 5 % solution of furocoumarin in ethyl alcohol – 10; water – balance.EFFECT: invention provides higher antimicrobial activity and stability of the active substance.1 cl, 2 tbl

Description

The invention relates to the field of hygiene and sanitation and can be used for disinfection and sanitation of the air of closed (livestock) premises.

Known disinfectant concentrate, which contains, by weight. %: hydrogen peroxide 35-40; soluble silver salt 1.0-2.0; aliphatic alcohol, mainly ethyl, isopropyl or propyl 0.05-1.0; the rest is water (RF patent No. 2187460) [1].

The disadvantages of the invention is that the tool does not have sufficiently high antibacterial properties.

The task of the invention is to increase the efficiency of the process of disinfection of indoor air.

The technical result of the invention is to increase the antimicrobial activity of the active substance.

The task and the specified technical result are achieved due to the fact that in the known means for disinfecting the air containing hydrogen peroxide, a soluble silver salt, an organic compound, according to the invention, a 5% solution of furocoumarin in ethyl alcohol is used as an organic compound, in the following ratio of components, wt. %: hydrogen peroxide - 5; silver salt - 1; 5% solution of furocoumarin in ethyl alcohol - 10; water is the rest.

Hydrogen peroxide has a universal antimicrobial effect. Gram-positive and gram-negative bacteria, viruses, many types of pathogenic fungi are sensitive to it. Causes the death of spores of most spore-forming bacteria (Matreninskaya ES A new generation of disinfectants based on hydrogen peroxide / Medical alphabet. Epidemiology and Sanitation, 2011, No. 1, p. 40) [2].

A wide range of antimicrobial effects of silver, low toxicity, lack of resistance to it in most pathogenic microorganisms and non-allergic silver make it possible to use it as an effective, harmless disinfectant (Kulsky L.A. Silver Water. - 9th ed., Rev. And add. - K .: Naukova Dumka, 1987. - 134 p.) [3].

Known antibacterial activity of derivatives of plant furocoumarin - peucedanin obtained from gorinik Morison (Shirokikh I.V., Burova L.G., Lipeeva A.V., Schulz E.E. Study of the antibacterial properties of peucedanin derivatives in relation to Staphylococcus aureus in vitro. / I.V. Shirokikh, L.G. Burova, A.V. Lipeeva, E.E. Schulz // Siberian Medical Bulletin. - 2018. - No. 2. - P. 8-12.) [4].

Furocoumarins derived from grapefruit juice inhibit the formation of biofilms of Escherichia coli, Salmonella typhimurium and Pseudomonas aeruginosa (Girennavar B., Cepeda ML, Soni KA, Vikram A., Jesudhasan P., Jayaprakasha GK, Pillai SDoufromar BS inhibits autoinducer signaling and biofilm formation in bacteria // Int. J. Food Microbiol. 2008, V. 125, P. 204-208) [5].

A disinfectant was obtained by mixing the listed ingredients in the indicated proportions (wt.%). As a source of furocoumarins, the drug Ammifurin was used. Of the silver salts, silver nitrate was used.

An example of the use of disinfectants for indoor air.

Indoors, a disinfectant was sprayed in the air. Spraying can be carried out using any device that allows you to dispense the amount of sprayed substance.

Total microbial contamination was determined by aspiration using the Krotov apparatus. Air samples were taken to determine its bacterial contamination before and after photocatalytic air disinfection. To determine the content of yeast-like and mold fungi, sowing was carried out on Saburo medium, total microbial contamination on simple agar. The air speed was 25 l / min for 40 minutes. Inoculated media were kept in a thermostat at (37 ± 1) ° C for 24 hours, then at room temperature for 24 hours, and then the grown bacterial colonies were counted and colony forming units (hereinafter - CFU) contained in 1 m ^{3 of} air were calculated .

In the process of air treatment with the proposed tool, there was a decrease in the total microbial contamination of seeds and molds (tables 1, 2).

The total microbial contamination is reduced on average by 4 times, the content of molds - by 8 times.

As can be seen from the tables, after applying the proposed means for disinfection of the air, the level of contamination of the premises is significantly reduced.

Claims (2)

A means for disinfecting the air of enclosed spaces containing hydrogen peroxide, a soluble silver salt, an organic compound, water, characterized in that a 5% solution of furocoumarin in ethyl alcohol is used as an organic compound, in the following ratio, wt.%: hydrogen peroxide five silver salt one 5% solution of furocoumarin in ethyl alcohol ten water rest