RU2694050C1 - Циклический пептид, подложка для аффинной хроматографии, меченое антитело, конъюгат антитела и лекарственного средства и фармацевтический препарат - Google Patents
Циклический пептид, подложка для аффинной хроматографии, меченое антитело, конъюгат антитела и лекарственного средства и фармацевтический препарат Download PDFInfo
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- RU2694050C1 RU2694050C1 RU2018114690A RU2018114690A RU2694050C1 RU 2694050 C1 RU2694050 C1 RU 2694050C1 RU 2018114690 A RU2018114690 A RU 2018114690A RU 2018114690 A RU2018114690 A RU 2018114690A RU 2694050 C1 RU2694050 C1 RU 2694050C1
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- Prior art keywords
- amino acid
- residue
- amino
- chloroacetyl
- cyclic peptide
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/50—Cyclic peptides containing at least one abnormal peptide link
- C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
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- A—HUMAN NECESSITIES
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/42—Proteins; Polypeptides; Degradation products thereof; Derivatives thereof, e.g. albumin, gelatin or zein
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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- A61K47/50—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates
- A61K47/51—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent
- A61K47/62—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient the non-active ingredient being chemically bound to the active ingredient, e.g. polymer-drug conjugates the non-active ingredient being a modifying agent the modifying agent being a protein, peptide or polyamino acid
- A61K47/65—Peptidic linkers, binders or spacers, e.g. peptidic enzyme-labile linkers
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
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- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3804—Affinity chromatography
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/13—Labelling of peptides
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/14—Extraction; Separation; Purification
- C07K1/16—Extraction; Separation; Purification by chromatography
- C07K1/22—Affinity chromatography or related techniques based upon selective absorption processes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K19/00—Hybrid peptides, i.e. peptides covalently bound to nucleic acids, or non-covalently bound protein-protein complexes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
- C07K7/04—Linear peptides containing only normal peptide links
- C07K7/08—Linear peptides containing only normal peptide links having 12 to 20 amino acids
-
- G—PHYSICS
- G01—MEASURING; TESTING
- G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
- G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
- G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
- G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
- G01N33/58—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving labelled substances
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/395—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
- A61K39/39516—Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum from serum, plasma
- A61K39/39525—Purification
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biochemistry (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Analytical Chemistry (AREA)
- Epidemiology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Urology & Nephrology (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Physics & Mathematics (AREA)
- Pathology (AREA)
- Cell Biology (AREA)
- Physics & Mathematics (AREA)
- Food Science & Technology (AREA)
- Gastroenterology & Hepatology (AREA)
- Inorganic Chemistry (AREA)
- Mycology (AREA)
- Peptides Or Proteins (AREA)
- Medicinal Preparation (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Applications Claiming Priority (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2015209030 | 2015-10-23 | ||
| JP2015-209030 | 2015-10-23 | ||
| JP2016-206753 | 2016-10-21 | ||
| PCT/JP2016/081353 WO2017069269A1 (ja) | 2015-10-23 | 2016-10-21 | 環状ペプチド、アフィニティクロマトグラフィー担体、標識化抗体、抗体薬物複合体、および医薬製剤 |
| JP2016206753A JP6554452B2 (ja) | 2015-10-23 | 2016-10-21 | 環状ペプチド、アフィニティクロマトグラフィー担体、標識化抗体、抗体薬物複合体、および医薬製剤 |
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| RU2694050C1 true RU2694050C1 (ru) | 2019-07-09 |
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| RU2018114690A RU2694050C1 (ru) | 2015-10-23 | 2016-10-21 | Циклический пептид, подложка для аффинной хроматографии, меченое антитело, конъюгат антитела и лекарственного средства и фармацевтический препарат |
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| US (1) | US10703778B2 (de) |
| EP (1) | EP3366693B1 (de) |
| JP (1) | JP6554452B2 (de) |
| KR (1) | KR102139057B1 (de) |
| CN (1) | CN108137651B (de) |
| AU (1) | AU2016340472B2 (de) |
| BR (1) | BR112018008117A2 (de) |
| CA (1) | CA3000979A1 (de) |
| RU (1) | RU2694050C1 (de) |
| SG (1) | SG11201803001WA (de) |
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| CA3036768A1 (en) * | 2016-09-30 | 2018-04-05 | Fujifilm Corporation | Cyclic peptide, affinity chromatography support, labeled antibody, antibody drug conjugate, and pharmaceutical preparation |
| JP7117741B2 (ja) * | 2018-10-10 | 2022-08-15 | 国立大学法人 鹿児島大学 | ＩｇＧ結合性ペプチドを含む固相担体及びＩｇＧの分離方法 |
| KR20220029571A (ko) * | 2019-05-24 | 2022-03-08 | 아비타이드 엘엘씨 | Aav9 친화성 제제 |
| WO2020250855A1 (ja) * | 2019-06-11 | 2020-12-17 | 富士フイルム株式会社 | 環状ペプチド、細胞足場材、細胞分離材、及び、培地 |
| WO2024195709A1 (ja) * | 2023-03-17 | 2024-09-26 | 富士フイルム株式会社 | 環状ペプチド又はその塩及びそれらの利用 |
| WO2024195711A1 (ja) * | 2023-03-17 | 2024-09-26 | 富士フイルム株式会社 | 環状ペプチド又はその塩及びそれらの利用 |
| WO2024195710A1 (ja) * | 2023-03-17 | 2024-09-26 | 富士フイルム株式会社 | 環状ペプチド又はその塩及びそれらの利用 |
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| US20040087765A1 (en) * | 2000-11-08 | 2004-05-06 | Wofgang Ronspeck | Peptides, the production and use thereof for binding immunoglobulins |
| EP2180054A1 (de) * | 1999-12-24 | 2010-04-28 | Genentech, Inc. | Verfahren und Zusammenstellungen zur Verlängerung der Entsorgungshalbzeiten von bioaktiven Verbindungen |
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| US5817752A (en) | 1996-06-06 | 1998-10-06 | La Jolla Pharmaceutical Company | Cyclic polypeptides comprising a thioether linkage and methods for their preparation |
| US6303576B1 (en) | 1999-04-21 | 2001-10-16 | Adherex Technologies Inc. | Compounds and methods for modulating β-catenin mediated gene expression |
| JP4229704B2 (ja) | 2001-04-18 | 2009-02-25 | ダイアックス、コープ | Ｆｃ領域ポリペプチドの結合分子 |
| EP1416951A1 (de) | 2001-08-08 | 2004-05-12 | Merck & Co., Inc. | Mch (melanin-concentrating hormone) -antagonisten |
| KR20040087765A (ko) | 2003-04-09 | 2004-10-15 | 주식회사 일산 | 관체 성형방법 및 그 장치 |
| CA2813049A1 (en) | 2010-09-23 | 2012-03-29 | The Trustees Of The University Of Pennsylvania | Modified compstatin with improved stability and binding properties |
| EP2749646B1 (de) | 2011-08-24 | 2018-03-21 | Kagoshima University | IgG-BINDENDE PEPTIDE UND VERFAHREN ZUR IG-G-ERKENNUNG UND -REINIGUNG DAMIT |
| CN105612174A (zh) * | 2013-07-25 | 2016-05-25 | 诺华股份有限公司 | 用于治疗心力衰竭的二硫化物环状多肽 |
-
2016
- 2016-10-21 JP JP2016206753A patent/JP6554452B2/ja active Active
- 2016-10-21 EP EP16857582.7A patent/EP3366693B1/de active Active
- 2016-10-21 RU RU2018114690A patent/RU2694050C1/ru active
- 2016-10-21 SG SG11201803001WA patent/SG11201803001WA/en unknown
- 2016-10-21 BR BR112018008117-5A patent/BR112018008117A2/pt not_active Application Discontinuation
- 2016-10-21 AU AU2016340472A patent/AU2016340472B2/en active Active
- 2016-10-21 KR KR1020187009948A patent/KR102139057B1/ko active IP Right Grant
- 2016-10-21 CA CA3000979A patent/CA3000979A1/en active Pending
- 2016-10-21 CN CN201680061489.0A patent/CN108137651B/zh active Active
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2018
- 2018-04-10 US US15/949,769 patent/US10703778B2/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP2180054A1 (de) * | 1999-12-24 | 2010-04-28 | Genentech, Inc. | Verfahren und Zusammenstellungen zur Verlängerung der Entsorgungshalbzeiten von bioaktiven Verbindungen |
| US20040087765A1 (en) * | 2000-11-08 | 2004-05-06 | Wofgang Ronspeck | Peptides, the production and use thereof for binding immunoglobulins |
Also Published As
| Publication number | Publication date |
|---|---|
| EP3366693A1 (de) | 2018-08-29 |
| CN108137651B (zh) | 2022-02-22 |
| SG11201803001WA (en) | 2018-05-30 |
| EP3366693B1 (de) | 2023-08-16 |
| BR112018008117A2 (pt) | 2018-11-06 |
| AU2016340472A1 (en) | 2018-05-10 |
| US20180230184A1 (en) | 2018-08-16 |
| AU2016340472B2 (en) | 2019-02-28 |
| JP2017095443A (ja) | 2017-06-01 |
| JP6554452B2 (ja) | 2019-07-31 |
| EP3366693A4 (de) | 2018-12-05 |
| KR20180041243A (ko) | 2018-04-23 |
| CA3000979A1 (en) | 2017-04-27 |
| CN108137651A (zh) | 2018-06-08 |
| KR102139057B1 (ko) | 2020-07-29 |
| US10703778B2 (en) | 2020-07-07 |
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